Some of the side effects of Eptus 25:
- Headache: Headache is a common side effect of Eptus 25. It may occur due to the medication's vasodilatory effect on blood vessels.
- Dizziness: Dizziness is another common side effect of Eptus 25. It may be due to the medication's ability to lower blood pressure.
- Fatigue: Eptus 25 may cause fatigue or tiredness, affecting the central nervous system.
- Hyperkalemia: Eptus 25 may cause an increase in serum potassium levels, which can lead to hyperkalemia. Patients should have their serum potassium levels monitored while taking Eptus 25.
- Nausea and vomiting: In some patients, Eptus 25 may cause nausea and vomiting. These symptoms are usually mild and short-term and do not require medication discontinuation. Patients may benefit from taking Eptus 25 with food to reduce the risk of nausea and vomiting.
- Diarrhoea: Eptus 25 may cause diarrhoea in some patients. Patients should be advised to report any persistent or severe diarrhoea to their healthcare provider.
- Increased creatinine levels in the blood: Eptus 25 may cause an increase in creatinine levels in the blood, which can indicate impaired kidney function.
- Cough: Cough is another common respiratory side effect of Eptus 25. It is usually dry and nonproductive and can be caused by the medication's effects on the lungs or throat.
Managing the Side Effects
Some natural remedies may help alleviate some of the side effects of the Eptus 25 tablet. Here are some potential options:
- Dizziness: Ginger and peppermint tea may help alleviate dizziness and improve digestion. However, they should not be used excessively as they may cause stomach upset.
- Diarrhoea: Probiotics such as yoghourt or kefir may help restore gut flora and alleviate diarrhoea. Chamomile tea may also help soothe the digestive tract.
- Nausea: Ginger is a well-known natural remedy for nausea. It can be consumed as a tea or in capsule form.
- Cough: Honey and lemon tea may help soothe coughs and sore throats. Eucalyptus oil may also be helpful when inhaled in a diffuser.
- Fatigue: Ginseng and ashwagandha are two herbs that may help improve energy levels and reduce fatigue.
- Increased potassium level in blood: Foods rich in potassium, such as bananas, sweet potatoes, and spinach, should be avoided or consumed in moderation if you have increased potassium levels in your blood.
- Increased creatinine level in blood: Drinking plenty of water may help flush out excess creatinine in the blood. Eating a balanced diet and avoiding high-protein foods may also help.
- Headache: Take plenty of rest and have a lot of water to stay hydrated. Massage with coconut oil may also be helpful when applied topically.
However, natural or herbal management of side effects should always be discussed with a healthcare provider before trying, as they may interact with medications and cause adverse effects.
Precautions
While Eptus 25 effectively treats hypertension and heart failure, it is essential to consider certain precautions and warnings before using it.
Pregnancy
Eptus 25 mg Tablet use in pregnancy is not suggested since insufficient research has been conducted to determine its safety. Your doctor will only prescribe this medication if the possible benefits outweigh the risks.
Breastfeeding
It is unknown whether Eptus 25 tablet passes into breast milk. Therefore, it is not recommended to use this medication during breastfeeding. If a woman needs to take this medication while breastfeeding, she should consult her healthcare provider.
Alcohol
It is not recommended to consume alcohol while taking Eptus 25 tablet as it may raise the likelihood of side effects such as dizziness and lightheadedness.
Liver
Eptus 25 mg Tablet is not advised if you have liver problems or if your liver function tests show abnormalities. Eptus 25 mg tablet is metabolised in your liver, and pre-existing liver issues can cause a buildup, resulting in severe liver damage.
Kidney
Eptus 25 tablet should be used cautiously in patients with kidney problems. Based on the severity of the condition, the dosage may need to be changed, and periodic kidney function tests may be necessary.
Using a Machine and Driving
Eptus 25 tablet may lead to dizziness and drowsiness, impairing your capability to drive or operate machinery. It would be best to avoid such activities until they know how Eptus 25 tablet affects them.
Allergy
Patients with a known allergy to any ingredients in Eptus 25 tablet should not use this medication.
Use In Children
The safety and efficacy of Eptus 25 tablet have not been established. Therefore, it is not recommended for use in children.
Use In Older Patients
Older individuals can take Eptus 25 pill; however, the dosage may need to be changed due to changes in kidney function caused by ageing.
Interaction
Drug-Drug Interactions
The Eptus 25 can interact with Medications, including
- Anti-fungal medications like Itraconazole or ketoconazole; fluconazole is used to treat fungal infections
- Antiviral medications such as ritonavir and nelfinavir are used to treat HIV.
- Antibiotics such as Erythromycin, clarithromycin, telithromycin, and rifampicin treat bacterial infections.
- Anti-depressants such as nefazodone used to treat depression can interact with Eptus 25 tablet as these drugs reduce the breakdown of Eplerenone, thereby prolonging its effect on the body.
- Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARB) jointly treat high blood pressure, heart disease, or particular kidney conditions. They may interact with eptus 25 tablet as these drugs may raise the possibility of high potassium levels in your blood.
- Lithium is usually given to manage manic depressive disorder or bipolar disorder. Using lithium together with diuretics and ACE inhibitors has been shown to increase lithium levels in the blood, which may lead to side effects such as loss of appetite; visual impairment; tiredness; muscle weakness; muscle twitches.
- Immune-suppressing drugs like Cyclosporin treats skin conditions such as psoriasis or eczema and curb rejection after organ transplantation. These drugs can lead to kidney problems.
- Non-steroidal anti-inflammatory drugs (NSAIDs) - pain killers such as ibuprofen, used to relieve pain, stiffness and inflammation. These drugs may lead to kidney problems.
- An anti-clotting drug like Warfarin: When taking warfarin, caution is advised since high blood levels of warfarin may alter how Eplerenone affects the body.
- Anti-seizure drugs such as carbamazepine, phenytoin, and phenobarbital are used, among others, to treat epilepsy and may increase the breakdown of Eplerenone and thus decrease its effect.
It is essential to inform your doctor of any vitamins, supplements, or herbal products you are taking, as they may interact with Eptus 25 tablet and affect its efficacy or increase the risk of side effects.
Drug-Food Interactions
There are no known drug-food interactions associated with Eptus 25 tablet. However, it is recommended to avoid consuming excessive alcohol as it may increase the risk of side effects associated with the medication.
Drug-Disease Interactions:
The Eptus 25 tablet may interact with specific diseases and health conditions, affecting its efficacy or increasing the risk of adverse effects.
- Low blood pressure: Eptus tablet may cause a decrease in blood pressure, which can be more significant in patients with already low blood pressure. Therefore, it should be used cautiously in patients with hypotension or antihypertensive medications.
- Coronary heart disease: Eptus tablet should be used cautiously in patients with coronary heart disease or a history of myocardial infarction, as it may increase the risk of cardiovascular events.
- Liver or kidney disease: Eptus tablet is metabolised in the liver and excreted by the kidneys, and its elimination may be impaired in patients with liver or kidney disease. Therefore, dosage adjustments may be necessary for these patients, and close monitoring of kidney function is recommended.
- Heart failure: Eptus tablet is indicated for treating heart failure with reduced ejection fraction. However, caution should be exercised in patients with severe heart failure, as it may increase the risk of hyperkalemia.
- High serum potassium: Eptus tablet may cause an increase in serum potassium levels, especially in patients with chronic kidney disease or diabetes mellitus. Therefore, serum potassium levels should be monitored regularly in these patients.
- Diabetes mellitus type 2: Eptus tablet may affect glucose metabolism, and caution should be exercised in patients with diabetes mellitus type 2. Blood glucose levels should be monitored regularly in these patients.
- Patients with nil urine output (anuria): The kidneys primarily eliminate Eptus tablet, and its elimination may be impaired in patients with anuria. Therefore, it is contraindicated in these patients.