Zita D Tablet 15

Glenmark Pharmaceuticals Ltd.

Strip of 15 Units

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MRP ~~₹223.5~~

₹183.27

₹14.90/Units

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Composition

Dapagliflozin (10 Mg) + Teneligliptin (20 Mg)

Strength:

10 MG

Zita-D Tablet is primarily used to manage type 2 diabetes mellitus. This combination medication belongs to the class of antidiabetic medications.

This medicine also aids in improving glycemic control in adults whose blood sugar levels are not adequately managed by diet, exercise and individual antidiabetic medications.

Taking this medicine should be as directed by your doctor. It's important to let your doctor know about any pre-existing conditions or if you are taking other medications before starting on this medicine. If you experience any side effects while on this medicine, consult your doctor immediately. To get the best results, continue taking the medication for the duration prescribed by your doctor.

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Zita-D Tablet is used for managing blood sugar levels in type 2 diabetes mellitus.

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Stick to the dose recommended by your doctor.
Remember, it's crucial not to stop taking Zita-D Tablet without discussing it with your doctor first.

Zita-D Tablet is taken orally.

Zita-D Tablet may have the following common side effects:

Genital mycotic infections: These are fungal infections in the genital area.
Urinary tract infections
Hypoglycaemia: This is a condition where your blood sugar levels drop below normal.
Increased urination
Nausea
Back pain
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zita-D Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypoglycaemia: Try taking Zita-D Tablet with food to manage this effect.
Nausea: If you feel nauseous, consider taking this medicine after meals to lessen this effect.

Zita-D Tablet consists of two active ingredients:

Dapagliflozin (10 mg): This component inhibits the sodium-glucose co-transporter 2 (SGLT2) in your body. SGLT2 is responsible for absorbing glucose from the kidneys and returning it to your bloodstream. By inhibiting SGLT2, dapagliflozin reduces glucose reabsorption, leading to an increased excretion of glucose in the urine and a decrease in blood sugar levels.
Teneligliptin (20 mg): This component inhibits dipeptidyl peptidase-4 (DPP-4), an enzyme in your body that breaks down incretin hormones. Incretin hormones, like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), help stimulate insulin secretion from your pancreas and suppress glucagon release in a glucose-dependent manner. By inhibiting DPP-4, teneligliptin enhances the effects of incretin hormones, thereby increasing insulin secretion and reducing glucagon levels, which ultimately lowers blood sugar.

Pregnancy

Zita-D Tablet is not recommended during pregnancy. If you are pregnant or planning to conceive, it is best to consult your doctor before using this medicine.

Breastfeeding

To understand the potential risks and benefits, it's best to consult your doctor.

Alcohol

It is advised not to consume alcohol while taking this medicine. Regular drinking can impact your blood sugar levels, making managing diabetes more difficult.

Liver

Caution is advised while taking Zita-D Tablet if you have any liver issues. It's best to discuss these with your doctor before starting this medication.

Kidney

Zita-D Tablet is not recommended for use in severe renal impairment or end-stage renal disease. If you have kidney problems, discuss them with your doctor before starting this medication.

Using Machines & Driving

There is no known interaction of Zita-D Tablet affecting your ability to drive or operate machinery. However, if you feel unwell or experience side effects like dizziness or fatigue, avoid such activities until you feel better.

Allergy

Zita-D Tablet should not be taken if you are allergic to dapagliflozin, teneligliptin or any other ingredients in the medicine. If you experience symptoms like rash, itching, swelling or difficulty breathing, seek immediate medical help.

Children

Zita-D Tablet should not be given to children below 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Zita-D Tablet under medical supervision as they may be more susceptible to its side effects, including dehydration and hypotension. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zita-D Tablet interacts with the following medicines:

Diuretics: If you take diuretics such as furosemide or hydrochlorothiazide with Zita-D Tablet, it could increase your risk of low blood pressure (hypotension) and dehydration.
Insulin and Insulin Secretagogues: If you are on insulin therapy or taking insulin secretagogues like glipizide or glimepiride, using Zita-D Tablet might increase the chances of low blood sugar (hypoglycemia). Your doctor might need to adjust your insulin or secretagogue dose.

Drug-Food Interactions

Drug-Disease Interactions

Zita-D Tablet interacts with the following diseases:

Hypotension: Zita-D Tablet can cause loss of fluids (volume depletion), leading to low blood pressure. If you have a history of hypotension, you should be cautious while taking this medicine.
Diabetic Ketoacidosis: Rare cases of diabetic ketoacidosis, a dangerous complication of diabetes that happens when your body starts running out of insulin, have been reported with medicines like Zita-D Tablet.
Kidney Disease: Zita-D Tablet is not recommended for individuals with severe kidney problems. If you have any kind of renal disease, use this medicine only under your doctor's supervision.
Genital Mycotic Infections: Medicines like Zita-D Tablet increase the risk of genital fungal infections. If you have a history of such infections, exercise caution while taking this medication.

Daily Dose

You should take your daily dose of Zita-D Tablet as prescribed by your doctor. The dosage might be adjusted based on factors like the severity of your condition and how you respond to the medication. Always follow the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

Accidentally taking more than your prescribed dose of Zita-D Tablet may lead to common side effects such as nausea, increased urination, and headache. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your regular dose of Zita-D Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Never adjust the dosage without consulting your doctor.

Keep your Zita-D Tablet in its original package to protect it from moisture.
Store at room temperature below 30°C.
Avoid exposure to direct sunlight and keep away from heat sources.
Ensure that the medicine is kept out of the reach of children.
Always check the expiry date before use, and do not use it if it has passed.

Engage in regular physical activity: Daily exercise helps improve insulin sensitivity, aiding your body in using the sugar in your bloodstream effectively, which can help you manage type 2 diabetes better.
Opt for a low-sugar diet: Eating foods with a low glycaemic index, like whole grains, can help manage your blood sugar levels and complement the effects of Zita-D Tablet.

Fact Box

Drug Category	SGLT2 Inhibitor, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Zita-D Tablet used for?

Zita-D Tablet is used to manage blood sugar levels in adults suffering from type 2 diabetes, alongside a proper diet and exercise.

How does Zita-D Tablet work?

Zita-D Tablet contains two active ingredients that work together to lower blood sugar: dapagliflozin increases glucose excretion in urine, while teneligliptin boosts insulin secretion.

Can Zita-D Tablet be used as the only medicine for managing type 2 diabetes?

No, Zita-D Tablet should be used as part of an overall diabetes management plan, which includes diet and exercise, not as a standalone treatment.

Is it safe for elderly patients to take Zita-D Tablet?

Yes, but they may be more vulnerable to hypotension and dehydration. It's advisable to consult a doctor before starting on Zita-D Tablet.

Can I use Zita-D Tablet if I have type 1 diabetes?

No, Zita-D Tablet is not meant for use in patients with type 1 diabetes. Consult your doctor for suitable alternatives.

What should I do if I forget to take my dose of Zita-D Tablet?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Never double up on doses.

Can I take Zita-D Tablet if I have severe kidney problems or am on dialysis?

No, Zita-D Tablet is not recommended for those with severe renal impairment, end-stage renal disease or those undergoing dialysis.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Dapagliflozin: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a614015.html
MICRO LABS LIMITED, INDIA. (n.d.). SUMMARY OF PRODUCT CHARACTERISTICS. https://rwandafda.gov.rw/wp-content/uploads/2022/11/TILYPTIN_20__TENELIGLIPTIN__TABLET-SMPC.pdf
Teneligliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11950
Singh, A. K. (2017). Efficacy and safety of teneligliptin. Indian Journal of Endocrinology and Metabolism, 21(1), 11. https://doi.org/10.4103/2230-8210.193163

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