Zenoxa 450 Mg Tablet 10

Zenoxa 450 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹246~~

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Composition

Oxcarbazepine (450 Mg)

Strength:

150 MG 300 MG 450 MG 600 MG

Zenoxa 450 Tablet is primarily used for the management of epilepsy and seizures, especially partial seizures. It belongs to a class of medication known as antiepileptics.

This tablet can also be used in combination with other antiepileptic medicines to manage the frequency of seizures. This may be particularly beneficial for adults and children aged 2 years and above, providing them with an increased level of control over their seizure episodes.

The dosage and frequency of the tablet should be decided by your doctor, taking into account factors like your age, weight, medical condition, and response to treatment. It's important you inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. Any side effects experienced while on this medication should be reported to your doctor promptly. Remember, it's crucial to continue the medicine for the duration prescribed by your doctor for optimal results.

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Zenoxa 450 Tablet is used for the following:

Controlling epilepsy, a neurological disorder characterised by recurrent seizures.
Managing partial seizures, a type of epilepsy where the electrical disturbance is limited to a specific area of the brain.
Assisting other antiepileptic medicines when used as an adjunctive therapy to enhance seizure control.
Managing seizure disorders in children aged 2 years and above, effectively reducing the frequency and intensity of their seizures.

Directions for Use of Zenoxa 450 Tablet 10

Swallow the tablet whole with a glass of water. Avoid breaking or chewing it.
You can take this medicine with or without food as per your comfort.
Do not exceed the dose prescribed by your doctor and follow their advice.
Abrupt discontinuation of this medicine can worsen seizures, so always consult your doctor before stopping.

Zenoxa 450 Tablet is taken orally.

The use of Zenoxa 450 Tablet could lead to the following side effects:

Dizziness
Drowsiness
Fatigue
Headache
Nausea, vomiting and stomach pain
Difficulty sleeping: This refers to insomnia or trouble in falling or staying asleep.
Constipation
Hyponatremia: This means low sodium levels in the blood which could cause symptoms like headache, nausea, restlessness, and fatigue.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zenoxa 450 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a few tips to manage common side effects:

Nausea and Stomach Pain: Try taking Zenoxa 450 Tablet with food or milk.
Difficulty Sleeping: Consider taking this medicine at night if it causes sleep disturbances.

Zenoxa 450 Tablet contains oxcarbazepine (450 mg), which has specific actions within the body:

Blocking Sodium Channels: Oxcarbazepine works by blocking voltage-sensitive sodium channels found in your brain. By doing so, it helps stabilise hyperactive neural membranes.
Inhibiting Neuronal Firing: By blocking these sodium channels, oxcarbazepine inhibits repetitive neuronal firing. This action contributes significantly to controlling seizure episodes.
Diminishing Synaptic Impulses: The propagation of synaptic impulses is diminished due to the actions of oxcarbazepine. This results in a reduced frequency of seizures.

Pregnancy

Caution is advised while taking Zenoxa 450 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If breastfeeding, the use of Zenoxa 450 Tablet should be discussed with your doctor to understand the potential risks and benefits.

Alcohol

Avoid consuming alcohol while taking Zenoxa 450 Tablet as it may enhance the sedative effects of the medicine.

Liver

Caution is advised while taking Zenoxa 450 Tablet in case of mild to moderate liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, it is a good idea to consult your doctor before taking Zenoxa 450 Tablet.

Using Machines & Driving

Zenoxa 450 Tablet may cause drowsiness and dizziness. Until you know how this medicine affects you, avoid driving or operating heavy machinery.

Allergy

Inform your doctor about any allergies to oxcarbazepine or related medicines before starting Zenoxa 450 Tablet .

Children

Care should be taken while giving Zenoxa 450 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Zenoxa 450 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zenoxa 450 Tablet interacts with the following medicines:

Antiepileptic Medicines: Medications like carbamazepine, phenytoin, and phenobarbital may interact with Zenoxa 450 Tablet. This interaction could influence the way your body processes these medicines and potentially alter their effects.
Calcium Channel Blockers: The effect of medicines such as amlodipine, felodipine and verapamil can be altered when taken with Zenoxa 450 Tablet.
Anticoagulants: The tablet may interact with anticoagulants like warfarin, possibly increasing the risk of bleeding.
Antidepressants: The effectiveness of antidepressants like fluoxetine could be affected by Zenoxa 450 Tablet.
Antipsychotics: There's a potential interaction with antipsychotics such as risperidone and haloperidol, which may change how these medicines work in your body.

Drug-Food Interactions

Zenoxa 450 Tablet interacts with certain foods:

Grapefruit Juice: This fruit juice could influence how your body absorbs and metabolizes oxcarbazepine, the active ingredient in Zenoxa 450 Tablet.

Drug-Disease Interactions

Zenoxa 450 Tablet interacts with the following diseases:

Kidney Disease: Patients with kidney disease should exercise caution as this medicine could worsen their condition.
Liver Disease: If you have liver disease, you need to be extra careful because Zenoxa 450 Tablet could exacerbate your condition.

Daily Dose

The recommended daily dose of Zenoxa 450 Tablet should be taken as directed by your doctor. Your dosage may vary depending on factors like how severe your condition is and how you react to the medicine. Always follow your doctor's instructions and never increase your dosage without consulting them first.

Over Dose

If you happen to take more Zenoxa 450 Tablet than recommended, you may experience symptoms like dizziness, drowsiness, and nausea. If these symptoms persist or worsen, inform your doctor.

Missed Dose

In case you forget to take your dose of Zenoxa 450 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage to make up for a missed dose without consulting your doctor.

Store Zenoxa 450 Tablet at a cool room temperature below 30°C.
Keep away from excessive light and moisture to maintain its efficacy.
Always keep this medicine out of the reach of children.
It's important to use the medicine before its expiry date.

Maintain a balanced diet with sufficient hydration. Dehydration can sometimes trigger seizures, so keeping your body well-hydrated may help in managing epilepsy.
As Zenoxa 450 Tablet helps manage seizures, it's beneficial to avoid potential seizure triggers like excessive caffeine or alcohol intake.

Fact Box

Drug Category	Sodium Channel Blocker
Therapeutic Category	Antiepileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Partial Seizures

What is Zenoxa 450 Tablet used for?

Zenoxa 450 Tablet is used to manage epilepsy and seizures, particularly partial seizures, in adults. It can be used alone or with other antiepileptic medicines.

How does Zenoxa 450 Tablet work?

The active ingredient in Zenoxa 450 Tablet, oxcarbazepine, blocks certain channels in the brain that are sensitive to electrical signals. This helps control and reduce the frequency of seizures.

Can I take Zenoxa 450 Tablet on an empty stomach?

Yes, it can be taken with or without food. But remember to swallow it whole with a glass of water without crushing or chewing it.

What should I do if I miss a dose of Zenoxa 450 Tablet?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue your regular schedule.

Can I stop taking Zenoxa 450 Tablet if my seizures are under control?

You should not stop taking Zenoxa 450 Tablet without consulting your doctor. Suddenly stopping the medicine may worsen your seizures.

Are there any side effects of taking Zenoxa 450 Tablet?

Common side effects include dizziness, drowsiness, headache, nausea and difficulty sleeping. If you experience any severe or persistent side effects, inform your doctor immediately.

Can I consume alcohol while taking Zenoxa 450 Tablet?

It is advised not to consume alcohol while taking Zenoxa 450 Tablet as it may enhance the sedative effects of the medicine.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Supernus, Inc. (2018). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/202810s010lbl.pdf
TRILEPTAL. (n.d.). TRILEPTAL. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021014s026,021285s021lbl.pdf
Oxcarbazepine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00776
Oxcarbazepine: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a601245.html

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