Tonact Ez 1040 Mg Tablet 10

Tonact Ez 40 Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹448.45~~

₹367.73

₹44.85/Units

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Composition

Atorvastatin (40 Mg) + Ezetimibe (10 Mg)

Tonact EZ 40 Tablet is primarily used to manage high cholesterol levels. This medicine is a combination of two active components, falling under the class of cholesterol-lowering medicines known as statins and cholesterol absorption inhibitors.

This medicine doesn't just manage high cholesterol levels but also works to balance the levels of "bad" cholesterol (LDL) and "good" cholesterol (HDL) in your blood. LDL cholesterol is reduced, and HDL cholesterol is increased, making it a two-pronged approach towards a healthier heart.

You should take this medicine orally as directed by your doctor. Make sure to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Tonact EZ 40 Tablet is used for the following:

Managing high cholesterol levels
Lowering "bad" cholesterol levels in your blood
Increasing "good" cholesterol in your blood
Reducing the risk of heart disease, heart attacks, and strokes
Helping when diet and lifestyle changes alone aren't enough to manage cholesterol levels

Directions for Use of Tonact Ez 40 Tablet 10

Here's how you should take Tonact EZ 40 Tablet:

Swallow the tablet whole with a glass of water.
Do not chew or crush the tablet.
Try taking it at the same time each day to maintain consistent blood levels.

Tonact EZ 40 Tablet is taken orally.

Taking Tonact EZ 40 Tablet might cause a few common side effects in some individuals:

Headache
Fatigue
Muscle pain or weakness
Nausea
Diarrhoea
Constipation
Joint pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Tonact EZ 40 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips for managing common side effects:

Nausea: Try taking Tonact EZ 40 Tablet with food.
Diarrhoea: Drink plenty of fluids to stay hydrated.

Tonact EZ 40 Tablet consists of two active ingredients:

Atorvastatin (40 mg): This statin works by blocking an enzyme called HMG-CoA reductase in your body. This particular enzyme plays a key role in creating cholesterol inside your body. By blocking the activity of HMG-CoA reductase, atorvastatin effectively lowers the levels of LDL cholesterol in your blood.
Ezetimibe (10 mg): As a cholesterol absorption inhibitor, ezetimibe works in your small intestine to block a specific transport protein responsible for absorbing cholesterol into your bloodstream. This action results in less cholesterol reaching your liver, which in turn leads to a reduction in overall blood cholesterol levels.

Pregnancy

Tonact EZ 40 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Tonact EZ 40 Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while drinking alcohol and taking Tonact EZ 40 Tablet. It's best to consult your doctor on this matter to avoid any potential harm.

Liver

Caution is advised while taking Tonact EZ 40 Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Using Machines & Driving

There are no known effects of Tonact EZ 40 Tablet on your ability to operate machinery or drive. However, if you experience side effects such as dizziness or fatigue, avoid any such activities until you feel better.

Allergy

If you have a known allergy to Atorvastatin or Ezetimibe, avoid taking Tonact EZ 40 Tablet. Make sure you inform your doctor about any allergies you may have.

Children

Caution is advised while giving Tonact EZ 40 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Tonact EZ 40 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Tonact EZ 40 Tablet interacts with the following medicines:

Cholesterol-lowering medicines: When taken with medicines like fibrates, niacin or bile acid sequestrants, it might alter the effectiveness of these medications.
Antibiotics: Medications like erythromycin and clarithromycin can increase the concentration of Atorvastatin in the blood, leading to an increased risk of side effects.
Antifungal medicines: When combined with antifungals such as itraconazole and ketoconazole, the risk of muscle damage may increase.
HIV protease inhibitors: These medications can increase the levels of Atorvastatin in your body, potentially increasing the risk of side effects.
Immunosuppressants: Cyclosporine, when taken alongside this medicine, can increase Atorvastatin levels in your body, leading to an increased risk of side effects.
Certain antidepressants: Nefazodone can increase the levels of Atorvastatin in your body, leading to a higher risk of side effects.

Drug-Food Interactions

Grapefruit juice should be avoided while taking Tonact EZ 40 Tablet as it can significantly increase the concentration of Atorvastatin in your blood, increasing the risk of side effects.

Drug-Disease Interactions

Tonact EZ 40 Tablet interacts with the following diseases:

Liver disease: Individuals with active liver disease or unexplained persistent elevations in liver function tests should avoid this medication as it can worsen their condition.
Kidney disease: This medicine should be used with caution if you have kidney disease as it could lead to an increased risk of muscle damage.
Diabetes: Diabetic patients need to monitor their blood sugar closely while on this medication as it may alter blood glucose levels.
Thyroid disorders: Patients with thyroid disorders should use this medicine cautiously as it can affect the metabolism of Atorvastatin and Ezetimibe.
Alcohol abuse: Regular consumption of alcohol can increase the risk of liver damage when taking Tonact EZ 40 Tablets.

Daily Dose

The daily dose of Tonact EZ 40 Tablet should be consumed as suggested by your doctor. The dosage might vary based on individual factors such as response to treatment and severity of the condition. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

Exceeding the prescribed dose of Tonact EZ 40 Tablet could lead to side effects such as muscle weakness and nausea. If you accidentally take more than the prescribed dosage, contact your doctor and discuss the situation.

Missed Dose

If you forget to take your regular dose of Tonact EZ 40 Tablet, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and continue with your regular dosing schedule. Never increase your dosage without consulting your doctor.

Store Tonact EZ 40 Tablet in a cool, dry place where the temperature stays below 30°C.
Shield the medicine from excessive light and moisture.
Always keep the medicine out of children's sight and reach.
Ensure to use the tablet before its expiry date.

Incorporate a low-cholesterol, high-fiber diet into your lifestyle. This supports the management of high cholesterol levels, which is what Tonact EZ 40 Tablet is used for.
Regular physical activity helps manage cholesterol levels. Aim for at least 150 minutes of moderate exercise, such as brisk walking or cycling, each week.

Fact Box

Drug Category	HMG CoA Reductase Inhibitor, Cholesterol Absorption Inhibitor
Therapeutic Category	Lipid-lowering Medication
Available Dosage Types	Tablet
Habit Forming	No
Ailment	High Cholesterol, Hypercholesterolemia

How long does it take for Tonact EZ 40 Tablet to start working?

It may begin to lower cholesterol levels within 2 weeks, but full effect may take up to 4 weeks.

Can I stop taking Tonact EZ 40 Tablet if my cholesterol levels improve?

No, you should not stop the medicine without consulting your doctor as your cholesterol levels may rise again.

Why cannot I consume grapefruit juice while taking Tonact EZ 40 Tablet?

Grapefruit juice can increase the risk of side effects and should be avoided whilst on this medication.

What should I do if I miss a dose of Tonact EZ 40 Tablet?

Take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule.

Is it safe to use Tonact EZ 40 Tablet during pregnancy or breastfeeding?

No, you should avoid this medicine during pregnancy or breastfeeding unless specifically directed by your doctor.

Can Tonact EZ 40 Tablet cause any side effects?

Yes, some common side effects include headache, fatigue, muscle pain or weakness, nausea, diarrhoea, constipation and joint pain.

How should I store Tonact EZ 40 Tablet?

Store it at room temperature (below 30°C) in a cool, dry place away from light and moisture. Keep out of reach of children and pets.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

References

MedlinePlus. (n.d.). Atorvastatin. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a600045.html
Atorvastatin: A medicine to treat high blood cholestesterol. (2022, March 16). Nhs.Uk. Retrieved 23 October 2024, from
https://www.nhs.uk/medicines/atorvastatin/
Ezetimibe: Medlineplus drug information. (n.d.). Retrieved 23 October 2024, from
https://medlineplus.gov/druginfo/meds/a603015.html
MedlinePlus. (n.d.). Ezetimibe. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a603015.html
U.S. Food and Drug Administration. (2009). Atorvastatin calcium tablets. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s057lbl.pdf
U.S. Food and Drug Administration. (2006). Zetia (Ezetimibe) tablets. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021445s014lbl.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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