Pth 30 Mg Tablet 10

Pth 30 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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Composition

Cinacalcet (30 Mg)

Strength:

60 MG 30 MG

PTH 30 Tablet is used predominantly for managing hyperparathyroidism, a condition marked by high levels of the parathyroid hormone (PTH). This medicine is part of the class known as calcimimetics.

This medicine also helps in managing hypercalcaemia in patients with parathyroid carcinoma and severe hypercalcaemia in those with primary hyperparathyroidism who cannot undergo parathyroidectomy.

This medicine should be taken orally as directed by your doctor. Remember to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, alert your doctor without delay. For optimal effectiveness, continue taking the tablet for the length of time prescribed by your doctor.

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PTH 30 Tablet is used for:

Managing secondary hyperparathyroidism in patients with chronic kidney disease on dialysis
Controlling hypercalcaemia in people diagnosed with parathyroid carcinoma
Reducing severe hypercalcaemia in patients with primary hyperparathyroidism who are unable to undergo surgery for parathyroidectomy

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Follow the dose recommended by your doctor.
Never alter the dosage without consulting your doctor.

PTH 30 Tablet is taken orally.

PTH 30 Tablet may have the following common side effects:

Nausea and vomiting
Diarrhoea
Headache
Dizziness
Muscle pain or weakness
Paresthesia: This is a sensation of tingling or numbness on your skin, often described as 'pins and needles'.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of PTH 30 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Nausea and vomiting: Try taking PTH 30 Tablet with food or shortly after a meal to lessen this effect.
Diarrhoea: If you experience diarrhoea after taking this medicine, consider taking it at night.

PTH 30 Tablet contains cinacalcet (30 mg), which acts on your body in the following ways:

Calcimimetic Agent: Cinacalcet mimics the action of calcium on receptors found in your parathyroid gland, known as calcium-sensing receptors.
Parathyroid Hormone Regulation: By acting like calcium, cinacalcet reduces the secretion of PTH from your parathyroid glands.
Controls Calcium and Phosphorus Levels: Lowering PTH levels results in decreased levels of serum calcium and phosphorus in your body.

Pregnancy

Caution is advised while taking PTH 30 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The safety of PTH 30 Tablet during lactation has not been established. It is recommended to consult your doctor if you are breastfeeding.

Alcohol

There is no known interaction between alcohol and the PTH 30 Tablet. However, it's always wise to check with your doctor about its safety.

Liver

If you have moderate to severe liver problems, you may require dose adjustments of PTH 30 Tablet as it is metabolised by the liver. Please consult your doctor for advice.

Kidney

PTH 30 Tablet is primarily used in managing conditions related to kidney health. However, caution is advised if you have kidney problems; it is recommended that you consult your doctor before starting this medicine.

Using Machines & Driving

This medicine may cause dizziness, therefore caution is advised while driving or operating machines.

Allergy

PTH 30 Tablet should not be used if you have a known allergy to cinacalcet or any of the inactive ingredients in the tablet.

Children

The safety and efficacy of PTH 30 Tablet in children have not been established. Therefore, caution is advised while giving this medicine to children under 18 years of age.

Older Patients

The safety and efficacy of PTH 30 Tablet in children have not been established. Therefore, caution is advised while giving this medicine to children under 18 years of age.

Drug-Drug Interactions

PTH 30 Tablet interacts with the following medicines:

Antidepressants: Medicines like desipramine may interact with PTH 30 Tablet as cinacalcet inhibits the enzyme that metabolises this medication.
Beta-blockers: PTH 30 Tablet might affect how your body processes certain beta-blockers such as metoprolol and carvedilol.
Antifungal medicines: Antifungals like ketoconazole and itraconazole, commonly used to manage fungal infections, can interact with PTH 30 Tablet, necessitating dose adjustments.

Drug-Food Interactions

No specific food interactions have been reported.

Drug-Disease Interactions

PTH 30 Tablet interacts with the following diseases:

Hypocalcaemia: PTH 30 Tablet can further decrease calcium levels in patients suffering from hypocalcaemia.
Liver Disease: Patients with moderate to severe liver disease may need dosage adjustments as cinacalcet is metabolised by the liver.

Daily Dose

The daily dose of PTH 30 Tablet should be as per your doctor's instruction, which may vary based on the severity of your condition and how you're responding to the medicine. It's crucial not to alter your dosage without consulting your doctor.

Over Dose

In case of an overdose of PTH 30 Tablet, you may experience symptoms like muscle spasms or irregular heartbeat due to severely low calcium levels. If this happens, inform your doctor.

Missed Dose

If you forget to take a dose of PTH 30 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store PTH 30 Tablet at room temperature, ideally below 30°C.
Keep the medicine in its original packaging to protect it from moisture and direct sunlight.
Ensure that the Tablet is kept out of reach of children at all times.
Remember to use the medicine before its expiry date.

For those with hyperparathyroidism or kidney disease, maintain a balanced diet with an appropriate intake of calcium and phosphorus. Consult your doctor for specific dietary guidelines.
Regular physical activity can help manage calcium levels in your body. Try to incorporate light exercises like walking or cycling into your daily routine, as advised by your doctor.

Fact Box

Drug Category	Calcimimetic Agent
Therapeutic Category	Hyperparathyroidism Manager
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Secondary Hyperparathyroidism, Parathyroid Carcinoma, Severe Hypercalcemia

What Is The PTH 30 Tablet Used For?

The PTH 30 Tablet is used to manage conditions like hyperparathyroidism and hypercalcaemia, typically seen in chronic kidney disease patients on dialysis.

How Does PTH 30 Tablet Work?

It contains cinacalcet that acts like calcium, fooling the parathyroid gland into reducing the production of parathyroid hormone, thus controlling the body's calcium and phosphorus levels.

What Are The Possible Side Effects Of PTH 30 Tablet?

Common side effects can include nausea, vomiting, diarrhoea, dizziness, and muscle pain. In rare cases, severe hypocalcaemia or abnormal heart rhythm may occur.

Can I Take PTH 30 Tablet If I'm Pregnant Or Breastfeeding?

Safety during pregnancy or lactation hasn't been established. It's crucial to consult your doctor if you are pregnant, planning to become pregnant or breastfeeding.

What Precautions Should I Take While Using PTH 30 Tablet?

Do not use if you are hypersensitive to cinacalcet or have low blood calcium levels. Inform your doctor if you have liver impairment or are pregnant.

What Should I Do If I Miss A Dose Of PTH 30 Tablet?

If you miss a dose, take it as soon as you remember unless it's close to your next dose time; in that case, skip the missed dose.

How Should I Store My PTH 30 Tablet?

Store your medicine below 25°C in its original packaging, keeping it away from children and protecting it from direct sunlight and moisture.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

FDA. (2011). FDA approved label August 1, 2011. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021688s017lbl.pdf
FDA. (n.d.). Sensipar® (cinacalcet) Tablets [Press-release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021688s013lbl.pdf
Teva Canada Limited. (2016). PRODUCT MONOGRAPH. https://pdf.hres.ca/dpd_pm/00037355.PDF
Cinacalcet: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01012
PubChem. (n.d.). Cinacalcet. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Cinacalcet
Kidney Research and clinical practice. (n.d.). https://www.krcp-ksn.org/m/journal/view.php?number=433

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