Psorid 100 Mg Capsule 5

Psorid 100 Capsule 5

Eris Oaknet Healthcare Pvt Ltd

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Composition

Cyclosporin (100 Mg)

Strength:

25 MG 50 MG 100 MG

Psorid 100 Capsule is primarily used to prevent organ rejection in patients who have undergone kidney, liver, or heart transplants. This medicine, an immunosuppressant, belongs to the class of drugs known as calcineurin inhibitors.

In addition to preventing organ rejection, this medicine is also used to manage severe cases of psoriasis and rheumatoid arthritis in adults. It plays a significant role in the prophylaxis of graft-versus-host disease in bone marrow transplantation.

Taking this medicine should be as directed by your doctor. Before commencing this medicine, it's crucial that you inform your doctor about any preexisting conditions or medications you're currently on. If you observe any side effects while on this medicine, promptly notify your doctor. For optimal results, continue taking the medicine for the duration advised by your doctor.

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Psorid 100 Capsule is used for the following:

Preventing rejection in kidney, liver and heart transplants
Managing severe, stubborn psoriasis in adults who aren't immunocompromised
Controlling severe active rheumatoid arthritis in adults
Preventing graft-versus-host disease in bone marrow transplantation

Directions for Use of Psorid 100 Capsule 5

Here's how you should take Psorid 100 Capsule:

Swallow the capsule whole with a glass of water. Do not chew or bite it.
Try to take this medicine at the same time each day to maintain a consistent level in your body.
Avoid consuming grapefruit and grapefruit juice as they can affect the absorption of this medicine.
Always follow your doctor's instructions on how to take this medicine.

Psorid 100 Capsule is taken orally.

Psorid 100 Capsule may cause the following common side effects:

High blood pressure
Tremors: You might feel shaking or trembling sensations.
Nausea
Diarrhoea
Headache
Hypertrichosis: This means excessive hair growth on the body.
Gingival Hyperplasia: This is a condition where your gums swell and start growing over your teeth.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Psorid 100 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

High blood pressure: Monitor your blood pressure regularly and report any significant changes to your doctor.
Nausea: Try taking Psorid 100 Capsule with meals to reduce feelings of nausea.

Psorid 100 Capsule contains cyclosporine (100 mg), which works on the body through the following mechanisms:

Inhibition of T-lymphocyte Activation: Cyclosporine forms a complex by binding with the cytosolic protein cyclophilin. This complex inhibits calcineurin, thereby preventing T-lymphocyte activation.
Suppression of Immune Responses: By acting selectively on T-lymphocytes, cyclosporine stops the production and release of interleukin2 (a protein that signals immune cells to grow and multiply). This mechanism inhibits both cell-mediated and humoral immune responses.
Prevention of Organ Rejection: The suppression of T-lymphocyte function interferes with the activity of effector T-cells, which play a crucial role in transplant rejection.

Pregnancy

Psorid 100 Capsule should be used during pregnancy only if the benefits outweigh the risks. Please consult your doctor before taking this medicine if you are pregnant.

Breastfeeding

Since Psorid 100 Capsule is known to be excreted in breast milk, it's advised not to breastfeed while on this medication. Always discuss with your doctor before making any decisions about breastfeeding.

Alcohol

There's no specific information about the interaction of Psorid 100 Capsule with alcohol. However, it's always a good idea to avoid alcohol as it can affect your overall health.

Liver

Caution is advised when using Psorid 100 Capsule if you have liver problems. This medicine can affect liver function, so discuss with your doctor before starting it.

Kidney

Psorid 100 Capsule can affect kidney function and is therefore not recommended for those with kidney issues. As always, discuss these concerns with your doctor before starting this medicine.

Using Machines & Driving

It's important to note that Psorid 100 Capsule can cause side effects like dizziness or blurred vision, which may affect your ability to drive or operate machinery. Do not drive or operate machinery until you know how this medicine affects you.

Allergy

Psorid 100 Capsule should not be used if you're allergic to cyclosporine or any other components of the medication. If you notice allergic symptoms like rash, itching, or difficulty breathing after taking the medicine, seek immediate medical help.

Children

The safety and efficacy of Psorid 100 Capsule in children for non-transplant indications have not been established. Always consult your doctor before giving this medicine to a child.

Older Patients

Elderly patients might need extra care while taking Psorid 100 Capsule as they may be more susceptible to its side effects, including kidney and liver issues. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Psorid 100 Capsule interacts with the following medicines:

Non-steroidal anti-inflammatory Drugs (NSAIDs): NSAIDs such as ibuprofen and diclofenac can increase the risk of kidney damage when taken with Psorid 100 Capsule.
Statins: Medications like atorvastatin or rosuvastatin used for managing cholesterol levels might interact with Psorid 100 Capsule, causing potential muscle damage.
Heart medications: Medications like digoxin may interact with this medicine, potentially leading to altered medicine effects or increased risk of side effects.
Gout medications: Allopurinol used for gout treatment can interact with Psorid 100 Capsule, increasing the risk of adverse reactions.

Drug-Food Interactions

Certain foods can interact with Psorid 100 Capsule.

Grapefruit: It affects the metabolism of cyclosporine, potentially leading to increased levels in the body and enhanced side effects.

Drug-Disease Interactions

Psorid 100 Capsule interacts with the following diseases:

Liver disease: Patients with liver disease should be cautious as this medication could potentially worsen their condition.
High blood pressure: Psorid 100 Capsule may cause hypertension, requiring monitoring and possible dose adjustment in patients already suffering from high blood pressure.
Kidney disease: This medicine can affect kidney function, and should be used carefully in patients with existing renal issues.

Daily Dose

You should take your daily dose of Psorid 100 Capsule exactly as your doctor prescribes. The dosage may vary depending on your individual health situation and how you respond to the medicine. Remember, it's important not to alter the dose without consulting your doctor. For further details regarding the dosage, kindly refer to the package insert.

Over Dose

If you accidentally take more Psorid 100 Capsules than prescribed, you might feel sick or have a headache. Please inform your doctor if these symptoms persist or worsen. Do not panic; ensure that you follow your regular dosage in the future.

Missed Dose

If you forget to take a dose of Psorid 100 Capsule, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Never double up on a dose to make up for a missed one without consulting your doctor.

Store your Psorid 100 Capsule protected from moisture at a temperature not exceeding 30°C.
Avoid storing in areas with high humidity or excessive heat.
Don't refrigerate the medication.
Keep this medicine out of the reach and sight of children.
Always check the expiry date before taking the capsule.

For people managing organ transplants: Maintain a balanced diet rich in fruits, vegetables and whole grains to support overall health while you're taking Psorid 100 Capsule.
If you're using Psorid 100 Capsule to manage severe psoriasis or rheumatoid arthritis, try gentle exercises like stretching or yoga to help improve joint flexibility and reduce inflammation.

Fact Box

Drug Category	Calcineurin Inhibitor
Therapeutic Category	Immunosuppressant
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Organ Rejection, Psoriasis, Rheumatoid Arthritis

What is Psorid 100 Capsule used for?

Psorid 100 Capsule is an immunosuppressant medicine used to prevent organ rejection in transplant patients and manage severe conditions like psoriasis and rheumatoid arthritis.

How does Psorid 100 Capsule work?

Psorid 100 Capsule contains cyclosporine, which works by reducing the activity of your body's immune system, hence preventing organ rejection or controlling autoimmune disorders.

Can I take Psorid 100 Capsule with food?

Yes, you should take Psorid 100 Capsule consistently with regard to meals, but avoid grapefruit as it can affect how the medicine works.

What are the common side effects of Psorid 100 Capsule?

Common side effects include high blood pressure, upset stomach, increased hair growth, and trembling. Make sure to consult your doctor if these persist.

Is Psorid 100 Capsule safe during pregnancy?

Psorid 100 Capsule should only be used during pregnancy if the benefits outweigh the risks. Always consult your doctor before taking any medication during pregnancy.

Can I have a vaccination while taking Psorid 100 Capsule?

Avoid live vaccines while on Psorid 100 Capsule, as they reduce your body's immune response. Always discuss vaccinations with your doctor beforehand.

How should I store my Psorid 100 Capsules?

Store your capsules at room temperature (not exceeding 30°C), protected from light and moisture. Avoid exposure to high humidity and temperatures above 30°C.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

References

U.S. Food and Drug Administration. (2016). Cyclosporine Oral capsule. https://www.accessdata.fda.gov/drugsatfda_docs/psg/Cyclosporine_Oral%20capsule_RLD%20050715_RV0416.pdf. Accessed 1 April 2024.
Tapia, C., Nessel, T. A., & Zito, P. M. (2023, August 28). Cyclosporine. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK482450/
Cyclosporine: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a601207.html

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