Oxetol 450 Mg Tablet 10

Oxetol 450 Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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Composition

Oxcarbazepine (450 Mg)

Strength:

300 MG 450 MG 600 MG 150 MG

Oxetol 450 Tablet is primarily used for managing partial seizures in adults and children aged 6 years and above. As part of the antiepileptic class of medications, this medicine can be used alone or in combination with other antiepileptic medicines to control seizures.

In addition to its main use, this tablet also plays a role in stabilising electrical activity within the brain, thus helping to manage the frequency and intensity of seizure episodes. It works by decreasing abnormal excitement in the brain, which is often associated with seizures.

You should take this medicine as directed by your doctor. Make sure you inform your doctor about any pre-existing health conditions or any other medications you are currently taking before starting this medicine. If you experience any side effects while taking this medicine, let your doctor know immediately. Remember to continue taking this medication for as long as your doctor recommends for optimal results.

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Oxetol 450 Tablet is used for the following:

Management of partial seizures in adults
Reducing the occurrence of partial seizures in children aged 6 years and above
Use as a standalone therapy for partial seizures
Use in combination with other antiepileptic medicines for managing partial seizures

Directions for Use of Oxetol 450 Tablet 10

Follow these instructions while taking Oxetol 450 Tablet:

Swallow the tablet whole with a glass of water.
Avoid cutting, crushing or chewing the tablet.
Take this medicine with or without food at your convenience.
Do not take more than the recommended dose without consulting your doctor.
It's important not to stop taking this medicine without speaking to your doctor first.

Oxetol 450 Tablet is taken orally.

While taking Oxetol 450 Tablet, you might experience some common side effects. These include:

Dizziness
Headache
Problems balancing
Nausea
Vomiting
Fatigue
Difficulty coordination
Double vision
Abdominal pain
Tremor

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Oxetol 450 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines to manage common side effects:

Nausea or Vomiting: Try taking Oxetol 450 Tablet with food or after meals to lessen this effect.
Dizziness or Balance disorder: If these symptoms occur after taking the tablet, consider taking it at bedtime.

Oxetol 450 Tablet contains oxcarbazepine (450 mg), which acts on the body as follows:

Voltage-Sensitive Sodium Channels Blockade: Oxcarbazepine works by blocking these channels found in your nerve cells. These channels play a vital role in the generation and conduction of electrical signals in the nervous system. By blocking these channels, oxcarbazepine helps stabilise overly excited nerve membranes.
Inhibition of Neuronal Firing: Oxcarbazepine decreases the repetitive firing of nerve cells. Repetitive neuronal firing is a key factor contributing to seizures. By reducing this firing, the medicine aids in controlling seizure episodes.
Diminution of Synaptic Impulse Propagation: This essentially means that oxcarbazepine reduces the spread of electrical signals from one nerve cell to another at synapses (the junctions where nerve cells meet). This action further assists in managing seizure activity.

Pregnancy

Caution is advised while taking Oxetol 450 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Oxetol 450 Tablet is not recommended for breastfeeding women. A decision should be made whether to discontinue nursing or discontinue the drug after consulting your doctor.

Alcohol

There's no specific information available about the interaction of Oxetol 450 Tablet with alcohol. However, it's always wise to avoid alcohol when you're on medication.

Liver

Caution is advised while taking Oxetol 450 Tablet in case of mild to moderate liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, caution is advised before using Oxetol 450 Tablet. Consult your doctor before taking this medicine.

Using Machines & Driving

Oxetol 450 Tablet may cause dizziness, drowsiness and visual disturbances. You should avoid driving or operating machinery until you know how it affects you.

Allergy

This medicine is contraindicated in patients with known hypersensitivity to oxcarbazepine or any components of the formulation.

Children

Caution is advised while giving Oxetol 450 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Oxetol 450 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Anti-epileptic medications: Oxetol 450 Tablet can enhance the levels of phenytoin, a medicine used to control seizures. This interaction could increase the risk of side effects from phenytoin.
Hormonal contraceptives: Oxetol 450 Tablet may decrease the effectiveness of hormonal contraceptives like birth control pills, patches, or injections. Therefore, you might need to consider alternative or backup methods of contraception.
Medicines affecting liver enzymes: Certain medications, such as phenobarbital, phenytoin and carbamazepine, can reduce the levels of Oxetol 450 Tablet in your body by increasing its breakdown in the liver. Conversely, medicines like cimetidine can increase Oxetol levels by reducing its breakdown.

Drug-Food Interactions

There are no specific food items known to interact with Oxetol 450 Tablet.

Drug-Disease Interactions

Kidney disease: If you have kidney disease, your doctor may need to adjust your dosage of Oxetol 450 Tablet, as this medicine is mainly eliminated through the kidneys.
Liver disease: Liver disease can affect how your body processes Oxetol 450 Tablet. Your doctor may monitor your liver function and adjust your medication if necessary.
Hyponatremia (low sodium levels): Oxetol 450 Tablet can cause low sodium levels in your blood. If you already have hyponatremia or are at risk for it, this medicine may worsen your condition.
Dermatological conditions: If you have a history of serious skin reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis, taking Oxetol 450 Tablet may increase the risk of these conditions recurring.

Daily Dose

Your doctor will prescribe the daily dose of Oxetol 450 Tablet based on your individual needs and response to treatment. Adhere to this prescribed dosage and refrain from exceeding it without your doctor's approval. For more detailed instructions, please refer to the package insert.

Over Dose

In case of an overdose, you may experience symptoms such as nausea, vomiting, and excessive sleepiness. If you notice these signs, kindly inform your doctor. Do not panic, but be sure to consult your doctor for further guidance.

Missed Dose

If you happen to miss a dose of Oxetol 450 Tablet, take it as soon as you remember. However, if it's nearly time for your next dosage, skip the missed one and continue with your regular schedule. It's vital not to increase your dose without consulting your doctor.

Store Oxetol 450 Tablet at room temperature.
Keep the product protected from light and moisture to maintain its efficacy.
Always keep this medicine out of the reach of children for safety reasons.
Ensure to use the medicine before its expiry date for optimal results.

Try to maintain a balanced diet. Some people with epilepsy may find that certain foods trigger seizures, so it might be beneficial to keep a food diary.
Regular exercise can help manage your overall health and stress levels, which can impact seizure frequency. However, avoid activities that could be dangerous should a seizure occur, such as swimming alone. Always discuss your exercise routine with your doctor.

Fact Box

Drug Category	Sodium Channel Blocker
Therapeutic Category	Antiepileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Partial Seizures

What is Oxetol 450 Tablet used for?

Oxetol 450 Tablet is used to manage partial seizures in adults and children aged 6 years and above.

How does Oxetol 450 Tablet work?

This medicine decreases the electrical activity in the brain that leads to seizures, thereby managing them effectively.

Can I take Oxetol 450 Tablet with my meal?

Yes, you can take this medicine with or without food, as per your doctor's advice.

What should I do if I miss a dose of Oxetol 450 Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Is Oxetol 450 Tablet safe during pregnancy and breastfeeding?

Oxetol 450 Tablet should be used during pregnancy and breastfeeding only if the potential benefits outweigh the risks. Always consult your doctor.

Can Oxetol 450 Tablet affect my contraceptive pill?

Yes, this medicine may decrease the effectiveness of hormonal contraceptives. Consider using an alternate or backup method of contraception.

What are the common side effects of Oxetol 450 Tablet?

Common side effects include dizziness, headache, balance disorder, nausea, vomiting, fatigue, and tremors, among others. Consult your doctor if these persist.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

References

U.S. National Library of Medicine. (n.d.). Oxcarbazepine- oxcarbazepine tablet. DailyMed. Retrieved April 1, 2024, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=abbf6b75-bc22-42af-ae08-445d8c186092&type=display
U.S. Food and Drug Administration. (n.d.). Oxcarbazepine- 202810- Clinpharm- PREA. FDA. Retrieved April 1, 2024, from https://www.fda.gov/files/drugs/published/Oxcarbazepine-202810-Clinpharm-PREA.pdf

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