Onglyza 5 Mg Tablet 14

Onglyza 5mg Tablet 14

Astrazeneca Pharma India Ltd

Strip of 14 Units

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Composition

Saxagliptin (5 Mg)

Strength:

5 MG 2.5 MG

Onglyza 5mg Tablet is primarily used to manage blood sugar levels in adults diagnosed with type 2 diabetes. It falls into a category of medications known as dipeptidyl peptidase-4 (DPP-4) inhibitors.

In addition to its main use, this medicine also comes into play as part of a comprehensive diabetes management plan that includes a healthy diet and regular exercise. It's not a replacement for these lifestyle measures but works in conjunction with them to help maintain normal blood sugar levels.

Before starting this medicine, it's crucial to consult your doctor, who will determine the appropriate dosage and frequency for you. Make sure to inform your doctor about any current medical conditions or medications you're on. If you notice any side effects while taking this medicine, notify your doctor promptly. It's also important to continue taking the medicine for the entire duration prescribed by your doctor for the best results.

Onglyza 5mg Tablet is used for the following:

Improving blood sugar control in adults with type 2 diabetes
As an adjunct to diet and exercise for better glycemic control in type 2 diabetes
Managing type 2 diabetes in combination with other oral antidiabetic agents such as metformin, sulfonylureas, or thiazolidinediones

Directions for Use of Onglyza 5mg Tablet 14

Here's how you should take Onglyza 5mg Tablet:

Swallow the tablet whole with a glass of water.
Do not crush, cut or chew the tablet.
For specific dosage instructions, consult your doctor.

Onglyza 5mg Tablet is taken orally.

Onglyza 5mg Tablet might have the following side effects:

Upper respiratory tract infection
Urinary tract infection
Headache
Pancreatitis: This is a condition where your pancreas, an organ which helps in digestion and blood sugar regulation, becomes inflamed.
Hypersensitivity reactions: These are exaggerated responses by your immune system to substances it considers harmful.
Joint pain
Hypoglycaemia: This is a condition where your blood sugar levels drop lower than normal.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Onglyza 5mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage two possible side effects:

Hypoglycaemia: Carry a source of fast-acting glucose such as hard candies or juice in case you experience hypoglycaemic symptoms.
Pancreatitis: If you experience symptoms of pancreatitis like severe stomach pain, try taking Onglyza 5mg Tablet with food.

Onglyza 5mg Tablet contains Saxagliptin (5mg), which has specific actions on your body:

Incretin Hormone Regulation: Saxagliptin slows down the inactivation of incretin hormones GLP-1 and GIP. These hormones are naturally released by your intestines throughout the day and their release increases in response to a meal. By slowing their inactivation, Saxagliptin prolongs their action.
Insulin Production Increase: With the increased and prolonged action of GLP-1 and GIP hormones, Saxagliptin promotes the production of insulin when your blood sugar levels are high.
Reduction of Glucagon Secretion: Along with increasing insulin production, Saxagliptin also reduces the secretion of glucagon, a hormone which raises blood sugar levels. This dual action helps to maintain balanced blood sugar levels.

Pregnancy

Caution is advised while taking Onglyza 5mg Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The safety of Onglyza 5mg Tablet during breastfeeding is not established. Please consult your doctor before using this medicine if you're nursing.

Alcohol

There's no known interaction between Onglyza 5mg Tablet and alcohol, but it's always a good idea to discuss your drinking habits with your doctor.

Liver

If you have liver problems, caution is advised when taking Onglyza 5mg Tablet. It's recommended to discuss any liver-related concerns with your doctor before starting this medication.

Kidney

Caution is advised if you have any kidney issues before using Onglyza 5mg Tablet. It's wise to consult your doctor before starting this medication.

Using Machines & Driving

Onglyza 5mg Tablet does not usually affect your ability to drive or operate machines. However, if you experience dizziness or other side effects that might affect your concentration, avoid these activities until you feel well enough.

Allergy

If you have a history of serious hypersensitivity reactions like anaphylaxis or angioedema, taking Onglyza 5mg Tablet may not be advisable. Always inform your doctor about any allergies before starting a new medication.

Children

Older Patients

Older patients should use Onglyza 5mg Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your overall health status.

Drug-Drug Interactions

Onglyza 5mg Tablet interacts with the following medicines:

Antifungals: Medicines such as Ketoconazole can significantly increase saxagliptin exposure, necessitating a lower dose of Onglyza 5mg Tablet.
Antibiotics: When taken together with Onglyza 5mg Tablet, medications like Rifampin can decrease saxagliptin absorption, potentially requiring a higher dose of the diabetes medicine.

Drug-Food Interactions

Onglyza 5mg Tablet does not have any known interactions with specific foods.

Drug-Disease Interactions

Onglyza 5mg Tablet interacts with the following diseases:

Pancreatitis: If you have a history of pancreatitis, exercise caution when taking Onglyza 5mg Tablet as it may worsen your condition.
Gallstones: Use of this medication should be carefully considered if you have gallstones, as it can exacerbate symptoms.
Renal Impairment: Frequent monitoring for glycemic control is necessary for patients with renal impairment taking Onglyza 5mg Tablet.

Daily Dose

You should take the daily dose of Onglyza 5mg Tablet as prescribed by your doctor. The dosage may vary depending on factors such as the severity of your condition and how you respond to the medicine. Always comply with the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you happen to take more Onglyza 5mg Tablets than recommended, you might experience symptoms like a headache, drowsiness, and confusion. Do not panic but inform your doctor about this.

Missed Dose

If you forget to take your Onglyza 5mg Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, leave out the missed one and continue with your regular schedule. Avoid increasing your dosage without discussing it with your doctor first.

Store your Onglyza 5mg Tablet at room temperature, ideally below 30°C.
Protect it from light and moisture by keeping it in the original packaging.
Make sure this medicine is out of reach from children.
Check the expiry date before taking the medicine; outdated products should be discarded safely.

For managing your type 2 diabetes, maintain a balanced diet low in sugar. Foods high in fibre like whole grains, fruits, and vegetables can help control blood sugar levels.
Regular physical activity is also beneficial. Try to incorporate at least 30 minutes of moderate-intensity exercise like brisk walking into your daily routine. Remember to consult with your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Dipeptidyl Peptidase-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is the main function of Onglyza 5mg Tablet?

Onglyza 5mg Tablet helps manage blood sugar levels in adults with type 2 diabetes, enhancing their insulin production and decreasing glucagon secretion.

How should I take my Onglyza 5mg Tablet?

Onglyza 5mg Tablet is taken orally, with or without food. The tablet should be swallowed whole, and not crushed, cut, or chewed.

What should I do if I forget to take my Onglyza 5mg Tablet?

If you miss taking your Onglyza 5mg Tablet, take it as soon as you remember. However, skip the missed dose if it's nearly time for your next one.

Can I take Onglyza 5mg Tablet along with other medications?

Yes, but always inform your doctor about all the medicines you are currently taking, including over-the-counter medicationsand supplements, to avoid any potential interactions.

What are some common side effects of the Onglyza 5mg Tablet?

Common side effects include upper respiratory tract infection, urinary tract infection, and headache. More serious side effects can also occur but are less common.

What signs of hypoglycaemia should I look out for while taking Onglyza 5mg Tablet?

Symptoms of hypoglycaemia may include confusion, drowsiness, dizziness, fast heartbeat, irritability, sweating, tremor or feeling jittery.

How should I store my Onglyza 5mg Tablets?

Store your Onglyza 5mg Tablets at room temperature, away from light and moisture. Do not store them in the bathroom or freeze them.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Highlights of prescribing information. (2015). [Prescribing Information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022350s016lbl.pdf
AstraZeneca. (2009). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022350s014lbl.pdf
ASTRAZENECA CANADA INC. (2021). PRODUCT MONOGRAPH Onglyza 5mg Tablet saxagliptin tablets (as saxagliptin hydrochloride) 2.5 and 5 mg. https://www.astrazeneca.ca/content/dam/az-ca/downloads/productinformation/Onglyza 5mg Tablet-product-monograph-en.pdf
DailyMed - Onglyza 5mg Tablet- saxagliptin tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d45fc842-2563-4421-86af-a55b3191e19b
Saxagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06335

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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