Olmezest H 20125 Mg Tablet 10

Olmezest H 20 Tablet 10

Sun Pharma Laboratories Ltd.

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Composition

Hydrochlorothiazide (12.5 Mg) + Olmesartan Medoxomil (20 Mg)

Olmezest H 20 Tablet is primarily used to manage essential hypertension in adults. This medicine is a combination medication, part of a group of medicines known as antihypertensives.

In addition to managing high blood pressure, this tablet can also be used in combination with other antihypertensive agents. This makes it a versatile option for controlling blood pressure levels effectively.

Before you start taking this medicine, consult your doctor about the correct dosage and frequency. It's important to inform your doctor about any pre-existing medical conditions or ongoing medications you are currently taking. If you notice any side effects while on this medicine, notify your doctor immediately. For the best results, continue taking the medicine for the duration prescribed by your doctor.

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Olmezest H 20 Tablet is used for managing the following conditions:

Controlling essential hypertension in adults
Providing an additive effect when combined with other antihypertensive agents, resulting in a greater reduction in blood pressure

Directions for Use of Olmezest H 20 Tablet 10

To use Olmezest H 20 Tablet properly, follow these steps:

Swallow the tablet whole with water. Do not crush or chew it.
You can take this medicine with or without food.
Try to take the tablet at the same time each day for consistent effect.
If you miss a dose, take it as soon as you remember. But if it's already near the time for your next dose, skip the missed one.
Never double dose to make up for a forgotten tablet.
Always consult your doctor before changing your dosage or stopping this medication.

Olmezest H 20 Tablet is taken orally.

Olmezest H 20 Tablet may have the following common side effects:

Dizziness: This means you might feel light-headed or faint.
Hypotension: This is a medical term for low blood pressure.
Hyperkalemia: This refers to high levels of potassium in your blood.
Headache
Bronchitis: An inflammation of the lining of your bronchial tubes, which carry air to and from your lungs.
Diarrhoea
Fatigue: You might feel extremely tired or weak.
Nausea
Muscle spasm: This is when your muscle tightens up, and you can't control it.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Olmezest H 20 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Diarrhoea: Try taking Olmezest H 20 Tablet with food or milk.
Nausea: Consider taking this medicine after meals to lessen this effect.

Olmezest H 20 Tablet contains two active ingredients:

Hydrochlorothiazide (12.5 mg): This component works as a thiazide diuretic, which reduces the reabsorption of electrolytes in your kidneys' renal tubules. The result is an increase in urinary excretion of sodium and chloride, reducing intravascular volume and inducing vasodilation.
Olmesartan Medoxomil (20 mg): As an angiotensin II receptor blocker (ARB), Olmesartan Medoxomil inhibits the binding of angiotensin II to AT1 receptors in vascular smooth muscle. This causes vasodilation and reduces the secretion of vasopressin and the production and secretion of aldosterone, reducing blood pressure.

Pregnancy

Olmezest H 20 Tablet is not advised for use during pregnancy. This medicine can harm the foetus, especially in the second and third trimesters. Discussing this with your doctor if you are pregnant or planning to conceive is crucial.

Breastfeeding

Information on the use of Olmezest H 20 Tablet during breastfeeding is limited. Therefore, it's recommended that nursing mothers consult their doctors before taking this medicine.

Alcohol

While there is no known interaction between Olmezest H 20 Tablet and alcohol, excessive drinking can increase blood pressure and interfere with the medicine's effectiveness. It's advisable to limit your alcohol consumption while on this medication.

Liver

If you have liver disease or impairment, proceed with caution when using Olmezest H 20 Tablet. While no dosage adjustment is necessary for mild to moderate liver problems, it should be used with care in severe impairment.

Kidney

A lower initial dose of Olmezest H 20 Tablet may be considered for those with kidney conditions, especially moderate to severe impairment. Before starting this medicine, it's recommended that you talk to your doctor if you have any kidney health concerns.

Using Machines & Driving

This medication may cause side effects like dizziness, which could affect your ability to operate machinery or drive. Avoid performing such tasks until you know how you respond to the medicine.

Allergy

If you're allergic to olmesartan, hydrochlorothiazide, or any other sulfonamide-derived medications, you should avoid taking Olmezest H 20 Tablet.

Children

The safety and effectiveness of Olmezest H 20 Tablet have not been established for children. Always consult your doctor before giving any medication to a child.

Older Patients

While no significant differences were observed between older and younger patients using Olmezest H 20 Tablet, older individuals may show greater sensitivity. Due to potential liver and kidney health concerns, it's recommended that older patients take this medicine under medical supervision.

Drug-Drug Interactions

Olmezest H 20 Tablet interacts with the following medicines:

Renin-angiotensin system inhibitors: Medicines such as ACE inhibitors or aliskiren can interact with Olmezest H 20 Tablet, potentially increasing the risk of high potassium levels in your blood (hyperkalaemia).
Potassium-sparing diuretics and potassium supplements: Consuming these alongside Olmezest H 20 Tablet can increase the risk of hyperkalaemia.
Lithium-based medicines: When taken with Olmezest H 20 Tablet, these can increase the risk of lithium toxicity.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines like ibuprofen and naproxen, when consumed with Olmezest H 20 Tablet, may reduce blood pressure-lowering effects and increase the risk of renal dysfunction.
Cholesterol-lowering agents: Medicines like Colesevelam hydrochloride may reduce the absorption of olmesartan

Drug-Food Interactions

There are no known food interactions with this medicine.

Drug-Disease Interactions

Olmezest H 20 Tablet interacts with the following diseases:

Anuria: Patients suffering from anuria should avoid this medicine as it can worsen their condition.
Liver disease: People with liver disease should exercise caution while taking this medicine as it could exacerbate their condition.
Kidney disease: Patients with kidney problems should use this medication carefully as it can affect kidney function.

Daily Dose

Always take the Olmezest H 20 Tablet as your doctor directs. Your dosage may vary according to factors such as the severity of your condition and your response to the medicine. Never exceed the stipulated dosage without first consulting your doctor.

Over Dose

In case of an overdose, you may experience common side effects in a more pronounced manner. If you have taken more than the prescribed dose, do not panic; however, inform your doctor about it as soon as possible.

Missed Dose

If you miss a dose of Olmezest H 20 Tablet, take it as soon as you recall. But if it's almost time for the next dose, skip the one you missed and continue with your usual schedule. Do not increase your dose without speaking to your doctor.

Store Olmezest H 20 Tablet in a cool place.
Keep the medicine away from excessive light and moisture.
It's important to keep this medicine away from children.
Ensure you use the tablet before its expiry date.

Since Olmezest H 20 Tablet manages high blood pressure, it would be beneficial to limit your salt intake. Too much salt can cause your body to retain water, which increases blood pressure.
Regular physical activity can also help manage hypertension. Aim for moderate-intensity exercise such as walking or swimming for at least 2.5 hours a week. Always check with your doctor before starting any new exercise programme.

Fact Box

Drug Category	Angiotensin II Receptor Blocker, Thiazide Diuretic
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Essential Hypertension

What is Olmezest H 20 Tablet used for?

Olmezest H 20 Tablet is used to manage essential hypertension in adults. It helps lower high blood pressure, reducing the risk of heart-related health problems.

What are the active ingredients in Olmezest H 20 Tablet?

Olmezest H 20 Tablet contains two active ingredients: Hydrochlorothiazide (12.5 mg), a diuretic that helps remove excess salt and water, and Olmesartan Medoxomil (20 mg), a medication that relaxes blood vessels.

How does Olmezest H 20 Tablet work?

Hydrochlorothiazide reduces fluid retention by increasing urine production, while Olmesartan Medoxomil relaxes your blood vessels. Together, they effectively lower high blood pressure.

Can I take Olmezest H 20 Tablet with food?

Yes, you can take Olmezest H 20 Tablet with or without food. However, for best results, it's advisable to take it at the same time each day.

What should I do if I miss a dose of Olmezest H 20 Tablet?

If you miss a dose, take it as soon as possible. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule.

Are there any side effects of taking Olmezest H 20 Tablet?

Some common side effects include dizziness, hypotension (low blood pressure), fatigue, and nausea. If these persist or worsen, consult your doctor immediately.

Can pregnant women take Olmezest H 20 Tablet?

No, pregnant women should not take this medicine. It can cause harm to the foetus if taken during the second and third trimesters of pregnancy.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

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References

U.S. National Library of Medicine. (2021, March 15). Hydrochlorothiazide: MedlinePlus drug information. MedlinePlus. https://medlineplus.gov/druginfo/meds/a682571.html. Accessed on 1 April 2024.
National Library of Medicine. (2021, December 13). Olmesartan medoxomil: DailyMed. DailyMed. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c42da0af-84dd-4220-bd40-139be51e8c00. Accessed on 1 April 2024.
U.S. Food and Drug Administration. (2012, February 24). Approval package for: Application number: 020818Orig1s051. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2012/020818s051ltr.pdf. Accessed on 1 April 2024.
U.S. Food and Drug Administration. (2002). Label: Olmesartan medoxomil- olmesartan medoxomil tablet. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/21286lbl.pdf. Accessed on 1 April 2024.

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