Neomycin Cream 10 Gm

Neomycin Cream 10 GM

Alkem Laboratories Ltd.

Tube of 10 GM

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MRP ~~₹25~~

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₹2.50/GM

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Composition

Neomycin (0.5 %)

Neomycin Cream is primarily used to manage various skin infections caused by bacteria that are sensitive to it. This medicine belongs to the broad category of antibiotics known as aminoglycosides.

Besides its primary use, this cream is also beneficial in handling specific skin conditions such as infected wounds, impetigo, folliculitis, furunculosis, and ecthyma. It has shown effectiveness against a range of bacteria including Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and Proteus vulgaris.

Before starting this medication, it is crucial to consult your doctor who will guide you regarding the appropriate dosage and frequency. Make sure to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while using this medicine, notify your doctor without delay. Continue using the cream for the duration prescribed by your doctor for optimal results.

Neomycin Cream is used to manage the following conditions:

Infected wounds
Skin condition known as impetigo
Folliculitis (Inflammation of hair follicles)
Furunculosis (a condition characterised by boils)
Skin infection called ecthyma
Other primary skin infections caused by bacteria susceptible to neomycin

Directions for Use of Neomycin Cream 10 GM

Wash your hands before applying the cream to prevent any additional infection.
Apply a thin layer of the cream on the affected area.
Rub it gently into your skin until fully absorbed.
Follow this process as directed by your doctor.
Make sure you wash your hands after application as well.

Neomycin Cream is applied topically.

The use of Neomycin Cream may result in some side effects. The most common ones include:

Skin irritation
Redness
Itching
Burning sensation
Dryness
Rash

Rarely, you might also experience allergic reactions such as hives or difficulty breathing. If these occur, seek medical help immediately.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve as the body adjusts to the use of Neomycin Cream. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Skin irritation and redness: Clean the area with water and wait for the symptoms to subside.

Neomycin Cream contains neomycin (5 %) which works in the following ways:

Binds to 30S ribosomal subunit: Neomycin binds to the 30S ribosomal subunit within susceptible bacteria. This is a part of the bacteria's machinery that makes proteins.
Inhibits protein synthesis: By binding to this subunit, neomycin inhibits the process of protein synthesis within the bacterium. Proteins are essential for many functions within bacterial cells.
Leads to bacterial cell death: The inhibition of protein synthesis eventually causes the bacterial cell to die. This means that neomycin doesn't just slow down bacterial growth—it actively kills off the bacteria causing your infection.

Pregnancy

Caution is advised while using Neomycin Cream if you are pregnant. It is best to consult your doctor before using this medicine.

Breastfeeding

Caution should be exercised when using the cream while breastfeeding. It's essential to discuss this with your doctor.

Alcohol

Interactions between alcohol and Neomycin Cream are unlikely as it's a topical formulation. However, it's always wise to discuss any concerns with your doctor.

Liver

As Neomycin Cream is for external use, liver health issues rarely influence its use. However, if you have liver disorders, consult your doctor before starting this medication.

Kidney

Neomycin Cream should be used with caution in patients with kidney disorders, as systemic absorption of neomycin can affect kidney function. Consult your doctor if you have kidney health issues.

Using Machines & Driving

The use of machinery or driving isn't typically influenced by the application of Neomycin Cream. However, if you experience any adverse reactions that could hinder these activities, contact your doctor.

Allergy

This cream is contraindicated in patients allergic to neomycin or other components of the cream. If you have known hypersensitivity or have had allergic reactions in the past, avoid using this medicine without consulting your doctor.

Children

Neomycin Cream can be used in children under the guidance of a doctor. Use this medicine with caution and only when necessary as children may be more susceptible to side effects.

Older Patients

Older patients should use Neomycin Cream under medical supervision due to potential susceptibility to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Neomycin Cream interacts with the following medicines:

Corticosteroids: Topical creams like hydrocortisone could increase the absorption of neomycin into your body. Other topical medications could interact with the cream too and alter the effects of either medication.

Drug-Food Interactions

There are no known specific food interactions with Neomycin Cream. Since it is a topical medication, it does not directly interact with foods or beverages when used as directed.

Drug-Disease Interactions

Neomycin Cream interacts with the following diseases:

Kidney disorders: The active ingredient in this cream, neomycin, can cause kidney damage (nephrotoxicity) if absorbed into your body in large amounts. So, if you have any type of kidney disorder, using this cream over large areas of your skin or for prolonged periods might increase this risk.
Allergic reactions: If you are allergic to neomycin or other aminoglycoside antibiotics, applying Neomycin Cream could trigger an allergic reaction. Symptoms might include hives, swelling, or difficulty breathing.

Daily Dose

Your doctor will prescribe the correct daily dosage of Neomycin Cream for you. This might vary depending on factors like how severe your condition is and how well you respond to the medication. It's essential not to exceed this dosage without first consulting your doctor.

Over Dose

Applying too much Neomycin Cream can cause skin irritation, redness, and itching. If you have applied more than the recommended amount, clean the area with water. If any symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to apply your Neomycin Cream, do it as soon as you remember. But, if it's almost time for your next application, skip the missed one now and resume your regular schedule. Never increase your dosage without consulting your doctor.

Store Neomycin Cream at a cool room temperature.
Avoid exposure to excessive light and moisture to maintain the cream's effectiveness.
Always keep the cream in its original, tightly sealed container.
Keep this medicine out of reach of children to prevent accidental ingestion.
Use your cream before its expiry date for optimum results.

If you're using Neomycin Cream for a skin infection, maintaining proper hygiene is crucial. Clean the affected area with a mild soap and pat dry gently before applying the cream.
Allow your skin to breathe by wearing loose, cotton clothes. Tight clothing may rub against the infected area, causing irritation and potentially worsening your condition.

Fact Box

Drug Category	Protein Synthesis Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Cream
Habit Forming	No
Ailment	Wounds, Impetigo, Folliculitis

What is Neomycin Cream used for?

Neomycin Cream manages skin infections caused by bacteria sensitive to neomycin, including infected wounds, impetigo, folliculitis, furunculosis, and ecthyma.

How does Neomycin Cream work?

The active ingredient, neomycin, binds to bacterial cells and disrupts their protein production, leading to bacterial cell death and managing the infection.

How should I apply Neomycin Cream?

Apply a thin layer of Neomycin Cream on the infected area as directed by your doctor. Rub it gently until absorbed.

Can Neomycin Cream be used for acne?

No, Neomycin Cream is not suitable for managing acne as the bacteria causing acne are not affected by neomycin.

Can I use Neomycin Cream on an open wound?

Yes, apply Neomycin Cream gently on open wounds to manage bacterial infections. Always consult your doctor first.

Is it safe for children to use Neomycin Cream?

Yes, under a doctor's guidance, children can use Neomycin Cream. But it must be used cautiously due to potential side effects.

Will using Neomycin Cream lead to antibiotic resistance?

Prolonged or improper use might lead to antibiotic-resistant bacteria, so always use it as prescribed by your doctor.

Last Updated On 07 May. 2024 | 3:58PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

References

Veirup, N., & Kyriakopoulos, C. (2023, November 12). Neomycin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK560603/
Neomycin topical: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682274.html
Neomycin. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00994

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