Levoflox 500 Mg Tablet 10

Levoflox 500 Tablet 10

Cipla Ltd.

Strip of 10 Units

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Composition

Levofloxacin (500 Mg)

Strength:

500 MG 250 MG

Levoflox 500mg tablet is an antibiotic commonly prescribed to treat bacterial infections. It comes under the class of drugs called fluoroquinolones and is effective in treating various infections, including urinary tract infections, pneumonia, sinusitis, and skin infections.

Levoflox 500 mg tablet 500mg fights against a broad spectrum of gram-positive and gram-negative bacteria. The medication works by interfering with the DNA replication process in bacteria, ultimately resulting in the bacteria's death.

Common side effects of Levoflox 500 mg tablet include nausea, diarrhoea, headache, and dizziness. Rare but severe side effects include tendonitis and rupture, peripheral neuropathy, and allergic reactions. Patients should contact their healthcare provider immediately if they experience any signs of these severe side effects.

The medication is available in oral tablet form and is rapidly absorbed into the bloodstream after ingestion. It is crucial to complete the entire course of treatment, even if symptoms improve before the medication is finished.

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Levoflox 500 mg tablet is an antibiotic that treats various bacterial infections. Some of the primary uses of Levoflox 500 mg tablet include

Pneumonia - An infection that swells the air sacs (alveoli) in one or both lungs. The alveoli may get filled up with fluid or pus, leading to cough with phlegm or pus, fever, chills, and difficulty breathing.
Chronic bronchitis is the swelling of airways and lung passages. Levoflox 500 mg tablet aid in treating chronic bronchitis.
Prostatitis is swelling of the prostate gland,
Acute Pyelonephritis- Levoflox 500 MG Tablet treats a sudden and severe kidney infection (upper urinary tract) caused by bacteria. Acute pyelonephritis causes the kidneys to swell and may permanently damage them.
Urinary tract infection - Bacteria may cause infection in any part of your urinary system (the kidneys, bladder and urethra). The symptoms associated with these infections are pain, swelling, difficulty in urinating, nausea and vomiting. Levoflox 500 MG Tablet treats urinary tract infections caused by bacteria.

Directions for Use of Levoflox 500 Tablet 10

Levoflox 500 mg tablets should be taken exactly as your doctor prescribes.

It is best taken after a meal. Do not cut, break, or chew the medicine; swallow it whole with a glass of water.

Do not take Levoflox 500 mg tablets for a long time without consulting a doctor.

Levoflox 500 mg tablet is taken orally.

The common side effects of Levoflox 500 mg tablet are as follows:

Nausea and vomiting: Nausea and vomiting are side effects of Levoflox 500 mg tablet and can be caused by stomach lining irritation.
Diarrhoea: Diarrhoea may occur due to changes in the gut microbiome caused by antibiotics, including Levoflox 500 mg tablet. In rare cases, Levoflox 500 mg tablet can cause severe diarrhoea, known as Clostridium difficile-associated diarrhoea.
Indigestion: Indigestion is also a possible side effect of Levoflox 500 mg tablet. These symptoms may be related to gut microbiome changes or how the medication affects gastrointestinal motility.
Trouble sleeping or insomnia: Trouble sleeping or insomnia is another common side effect of Levoflox 500 mg tablet. This may be related to the medication's effects on the central nervous system, which can cause changes in sleep patterns.

Managing the Side Effects:

Most of the side effects are temporary and harmless, and get resolved by discontinuing the tablet. These may not require medical attention. To combat abdominal discomfort, take this tablet with food. If you experience severe or persistent side effects from this tablet, consult your doctor.

Levoflox 500 mg tablet is an antibiotic in the fluoroquinolone class. It inhibits bacterial DNA synthesis by targeting DNA gyrase and topoisomerase IV enzymes. The accumulation of damaged bacterial DNA eventually results in the death of the bacterial cell.
Levofloxacin has high bioavailability and a long half-life, allowing for once-daily dosing and excellent tissue penetration. It is effective in treating respiratory and other bacterial infections. Levoflox 500 mg tablet has a low propensity for developing bacterial resistance.

Pregnancy

Consuming Levoflox 500 mg tablet in pregnancy is not advisable as it may harm the foetus. However, there are no adequate studies on pregnant women. Levoflox 500 mg tablet should be used in pregnancy only if the potential benefit exceeds the potential risk to the foetus. Always consult your doctor before taking Levoflox 500 mg tablet.

Breastfeeding

Levoflox 500 mg tablet should be used with caution during breastfeeding. Studies have shown that the medication may be harmful to the developing fetus and can also be passed into breast milk. Always consult your doctor before taking Levoflox 500 mg tablet.

Alcohol

Consumption of alcohol should be avoided while taking Levoflox 500 mg tablet as it can increase the risk of harmful effects such as dizziness and drowsiness.

Liver

It is recommended that people with the liver disease take precautions while using Levoflox 500 mg Tablets. There is a possibility that the dosage of the Levoflox Tablet must be adjusted. Please talk to your doctor. However, it is not recommended for patients with severe liver disorders to take Levoflox 500 mg tablets.

Kidney

People with kidney disease should take precautions while using Levoflox 500 mg Tablet. There is a possibility that the dosage of the Levoflox 500 mg Tablet must be adjusted. Please talk to your doctor, however, it is not recommended for patients with severe liver disorders to take Levoflox 500 mg Tablet.

Using Machines & Driving

Levoflox 500 mg tablet may cause dizziness or drowsiness, affecting the ability to drive or operate machinery. Patients should avoid performing activities requiring mental alertness until they know how the medication affects them.

Allergy

Patients allergic to Levoflox 500 mg tablet or fluoroquinolone antibiotics should not use this medication.

Children

Levoflox 500 mg tablet should not be used in children under 18, as it may cause damage to growing bones and joints.

Older Patients

Older patients may be more susceptible to the side effects of Levoflox 500 mg tablet, such as tendonitis and tendon rupture. The medication should be used cautiously in this population; a lower dose may be necessary.

Drug-Drug Interactions

The Levoflox 500 mg tablet can interact with Medications, including

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve pain, reduce inflammation, and reduce high temperature.
Acidity relievers such as cimetidine can reduce the absorption of Levoflox 500 mg tablet and should not be taken within two hours before or after taking the medication.
Anti-tuberculosis drugs like probenecid may lead to an increased concentration of Levoflox 500 mg tablet in the blood, increasing the risk of side effects.
Immunosuppressants, such as cyclosporin, may lead to transplant rejection.
Anti-bacterial drugs like macrolides may increase the risk of adverse effects like central nervous system effects and tendonitis.
Blood sugar-lowering drugs such as insulin and glibenclamide may increase the blood sugar-lowering effects leading to hypoglycemia.
Blood thinners like warfarin may increase the risk of bleeding. Therefore, close monitoring of blood clotting parameters is recommended.
Fits medications (Phenytoin, valproate) may reduce the effectiveness of the fits medication.

Drug-Food Interactions

The Levoflox 500 mg tablet can interact with Foods, including

Dairy products: Certain foods can interact with Levoflox 500 mg tablet, resulting in impaired absorption and efficiency of the medicine. It is best to avoid dairy products two hours before or after taking Levoflox 500 mg tablet, as they can bind to the medicine and inhibit its absorption.
Alcohol and caffeine: It is also advised to avoid coffee and alcohol while taking Levoflox 500 mg tablet, as they can aggravate specific side effects such as anxiety and insomnia.

Drug-Disease Interactions

The Levoflox 500 mg tablet can interact with Diseases, including

Colitis: Levoflox 500 mg tablet can disrupt the natural gut flora and lead to the overgrowth of harmful bacteria.
Myasthenia gravis: Levoflox 500 mg tablet can exacerbate the symptoms of myasthenia gravis, a neuromuscular disorder that causes muscle weakness and fatigue.
Tendonitis: There have been reports of tendonitis and tendon rupture associated with fluoroquinolone antibiotics such as Levoflox 500 mg tablet.
Diabetes: Levoflox 500 mg tablet can cause changes in blood glucose levels, leading to hypoglycemia or hyperglycemia. Patients with diabetes should be closely monitored when taking Levoflox 500 mg tablet.
Hemodialysis: Levoflox 500 mg tablet is cleared by the kidneys and may accumulate in patients with kidney dysfunction, especially those undergoing hemodialysis. Dose adjustments may be necessary for these patients.
Kidney dysfunction: Levoflox 500 mg tablet can cause kidney damage in some patients.
Disease of nerves: Patients with a history of seizures or other central nervous system disorders may be at an increased risk of developing seizures while taking Levoflox 500 mg tablet. Caution is advised in such patients

Daily Dose

The recommended daily dose of Levoflox 500 mg tablets is once daily, with food, as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. Following the recommended dosage and consulting your doctor before exceeding it is essential.

Over Dose

If you or someone else takes an excessive amount of Levoflox 500 mg tablets by accident, it is necessary to take immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include headache, dizziness, nausea, constipation and diarrhoea.

Missed Dose

If you forgot to take a Levoflox 500 mg tablet, take it as soon as you remember. If the time for the next dosage is close, it is recommended to skip the missed one now and resume your regular dosage pattern or as instructed by your healthcare provider. Never increase your dosage without consulting your doctor.

Store this medicine at room temperature (15-25ºC).
Please protect it from light and moisture.
Keep Levoflox 500 mg tablet away from the reach of children.
Do not use Levoflox 500 mg tablet after the expiry date has passed.

When taking Levoflox 500 mg tablet, it is vital to maintain a balanced diet and drink plenty of fluids to prevent dehydration.
It is recommended to avoid dairy products, calcium-fortified products, and antacids containing calcium, magnesium, or aluminium within 2 hours of taking the medication.
Additionally, alcohol should be avoided as it can raise the risk of specific side effects, such as dizziness and drowsiness.
It is crucial to rest and avoid strenuous physical activity until the medication is completed to reduce the risk of tendonitis or tendon rupture.
Consult your healthcare provider if you want to modify your diet or lifestyle while taking Levoflox 500 mg tablet.

Fact Box

Drug Category	Fluoroquinolone
Therapeutic Category	Antibiotics
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Bacterial infections

Is Levoflox 500 mg tablet a powerful antibiotic?

Yes, Levoflox 500 mg tablet is a powerful antibiotic belonging to the fluoroquinolone class of antibiotics, commonly used to treat a wide range of bacterial infections.

How long does it take for Levoflox 500 mg tablet 500 mg to work?

Levoflox 500 MG Tablet begins to show its effect within 1-2 hours after taking it. But it could take up to three days for the infection's symptoms to disappear. Always finish your complete course of treatment, even if you feel better.

Why Levoflox 500 mg tablet is given once a day?

Levoflox, 500 mg tablet, is given once daily because it stays in the body long and can fight infections for 24 hours. Taking it once daily makes it easier for patients to follow their treatment plan. However, people with kidney problems may need a different dose. It's essential to follow the instructions from your doctor and finish the entire course of treatment to ensure the medication works well.

How many days Levoflox 500 mg tablet is used?

Levoflox 500 mg tablet treatment duration varies based on the type and severity of the bacterial infection being treated. The usual duration of treatment with Levoflox 500 mg tablet is 7-14 days.

Is Levoflox 500 mg tablet safe for kidneys?

Levoflox 500 mg tablet can be safe for kidneys when used appropriately and under the guidance of a healthcare provider. Levoflox 500 mg tablet is eliminated from the body primarily through the kidneys. However, in patients with pre-existing kidney problems, Levoflox 500 mg tablet may need to be used cautiously or at a lower dose. If the kidneys are not functioning correctly, there is a risk of drug accumulation in the body, which can lead to potential toxicity.

What foods should be avoided when taking Levoflox 500 mg tablet?

Levoflox should not be taken with milk, yoghurt, other dairy products, or calcium-containing beverages. Levofloxacin should be used at least 2 hours before or 4 hours after using antacids, mineral supplements, or vitamins.

How risky is Levoflox 500 mg tablet?

Levoflox 500 mg tablet can be associated with severe side effects, including tendon rupture, central nervous system effects, and increased risk of developing diarrhoea. It should only be used when other treatment options have failed or are unavailable.

Is it OK to take Levoflox 500 mg tablet at night?

Yes, it is generally okay to take Levoflox 500 mg tablet at night, as long as you follow the dosing instructions provided by your healthcare provider. Some people may prefer to take Levoflox 500 mg tablet at night to avoid potential adverse effects like dizziness or lightheadedness, which may be more noticeable during the daytime.

Can Levoflox 500 mg tablet damage the liver?

Although liver injury from Levoflox 500 mg tablet is uncommon, drugs in the same class (fluoroquinolones) are known to cause liver problems. They can lead to liver damage that can be severe, even causing death or long-term liver damage, and they may also affect the bile ducts. It's essential to use these medications under the guidance of a healthcare provider and monitor for any signs of liver problems.

Is Levoflox 500 mg tablet good for the lungs?

Levoflox 500 mg tablet can help treat some lung infections caused by bacteria like pneumonia, bronchitis, and COPD exacerbations.

Can I drink milk with Levoflox 500 mg tablet?

Do not take this medication with milk, yoghurt, or other dairy products that contain micronutrients like calcium. Although it's a vital micronutrient, the calcium in dairy products and antacids may bind to certain antibiotics, such as Levoflox 500 mg tablet, decreasing their absorption.

Does Levoflox 500 mg tablet make you pee a lot?

Yes, Levoflox 500 mg tablet can increase urine output (diuresis) in some patients due to its effect on the kidneys. However, increased urination is not a common side effect and may not occur in everyone taking the medication.

Does Levoflox 500 mg tablet affect the heart?

If you have low blood potassium or an abnormally slow heartbeat, Levoflox 500 mg tablet may raise your risk of irregular heartbeat, loss of consciousness, or fainting. If these symptoms appear, tell your doctor immediately.

Last Updated On 14 Feb. 2024 | 11:31PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

References

KD Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 713.
Vivek Podder, Nazia M. Sadiq. Levofloxacin 500 mg tablet. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. September 2022. [Accessed on 8th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK545180/
Actavis Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022]. [Accessed on 8th October 2022] https://www.medicines.org.uk/emc/files/pil.4625.pdf
Leeford Healthcare Limited. LEVELFOX 750. [Accessed on 8th October 2022] https://www.leeford.in/product/1021/levelfox-750

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