Forglyn 625 Mcg Respicap 30

Forglyn Respicap 30

Zydus Cadila

Bottle of 30 Units

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Composition

Formoterol Fumarate (6 Mcg) + Glycopyrrolate / Glycopyrronium (25 Mcg)

Forglyn Respicap is primarily used for the long-term management of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD). This combination medicine belongs to two classes of medicines - long-acting beta2-adrenergic receptor agonists (LABAs) and long-acting muscarinic antagonists (LAMAs).

In addition to managing COPD, this medicine can also help manage symptoms related to chronic bronchitis and emphysema. However, this medicine is not recommended for the relief of sudden breathing problems or the treatment of asthma.

Before you start taking this medicine, consult your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Long-term management of airflow obstruction in chronic obstructive pulmonary disease (COPD)
Maintenance treatment of chronic bronchitis
Maintenance treatment of emphysema

Directions for Use of Forglyn Respicap 30

Inhalation of the capsule contents is required, using the prescribed inhaler device.
The capsules should not be swallowed but inhaled.
The specific inhaler supplied with the medicine should be used.
Rinse your mouth with water after inhalation and spit it out.
For any further instructions or queries regarding usage, consult your doctor.

Forglyn Respicap is inhaled via inhaler device.

Upper respiratory tract infections: These are infections that can affect your nose, throat, and sinuses.
Nasopharyngitis: Also known as the common cold, this is an infection that affects your nose and throat.
Headache
Dry mouth
Urinary tract infections: These are infections in any part of your urinary system, which includes your kidneys, bladder, and urethra.
Cough
Paradoxical bronchospasm: This is when your airways tighten instead of opening up after using a bronchodilator medicine like Forglyn Respicap.
Nausea
Dizziness
Muscle spasms: These are sudden involuntary contractions of one or more muscles.
Tremor: This refers to an unintentional, rhythmic muscle movement involving to-and-fro movements of one or more parts of your body.
Palpitations: This is a sensation that your heart is beating too quickly or skipping beats.

Managing the Side Effects:

Here are some general guidelines for managing common side effects:

Dry mouth: Try drinking plenty of fluids and avoiding drinks with caffeine, as they can make your dry mouth worse.
Nausea: Consider administering Forglyn Respicap after eating if it makes you feel nauseous.

Forglyn Respicap contains two components:

Formoterol Fumarate (6 mcg): As a LABA, formoterol fumarate triggers a process inside cells that helps relax the muscles around your airways. This process involves an enzyme called adenyl cyclase and leads to wider airways and easier breathing. Formoterol fumarate has a greater affinity for beta2-adrenoceptors than beta1-adrenoceptors, which are different types of receptors in your body.
Glycopyrrolate (25 mcg): Functioning as a LAMA, glycopyrrolate blocks a substance called acetylcholine from acting on specific receptors known as muscarinic receptors found in your lung muscles. This action leads to a widening of the airways, improving airflow and making it easier for you to breathe. Glycopyrrolate binds particularly well to M3 muscarinic receptors and remains attached for longer periods.

Pregnancy

Caution is advised while taking Forglyn Respicap if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The use of this medication during breastfeeding should be based on an assessment of the risk-benefit ratio by your doctor.

Alcohol

It is always wise to limit alcohol consumption while on medication.

Liver

No dose adjustments are necessary for patients with liver impairment when using Forglyn Respicap. Still, it's a good idea to discuss your liver health with your doctor before starting this medicine.

Kidney

Forglyn Respicap should be used with caution if you have severe kidney problems. Do ensure you talk about this with your doctor before starting this medication.

Using Machines & Driving

Forglyn Respicap might cause dizziness in some individuals. If you experience such symptoms, avoid driving or operating heavy machinery until you feel better.

Allergy

If you have a history of hypersensitivity to formoterol, glycopyrrolate, or any ingredients in Forglyn Respicap, it is not recommended for you. Discontinue use immediately if signs of allergic reactions develop.

Children

Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients may be more susceptible to side effects of this medicine and should take it under medical supervision.

Drug-Drug Interactions

Anticholinergic Medicines: Concomitant use with medications like atropine or ipratropium may lead to additive adverse effects.
Strong CYP3A4 Inhibitors: Medicines such as ketoconazole or ritonavir may increase the systemic exposure to formoterol present in Forglyn Respicap.
Monoamine Oxidase Inhibitors (MAOIs) and Tricyclic Antidepressants (TCAs): When taken alongside Forglyn Respicap, medicines like selegiline (an MAOI) or amitriptyline (a TCA) may enhance the cardiovascular effects of formoterol.
Beta-Blockers: Medicines such as propranolol or metoprolol may counteract the effects of formoterol in Forglyn Respicap.

Drug-Food Interactions

No specific food interactions have been reported with Forglyn Respicap.

Drug-Disease Interactions

Narrow-Angle Glaucoma: The ingredient glycopyrrolate in Forglyn Respicap might worsen symptoms in patients with this eye condition.
Cardiovascular Disorders, Convulsive Disorders, Thyrotoxicosis, and Diabetes Mellitus: Patients with these conditions should use Forglyn Respicap with care, as formoterol may exacerbate these conditions.

Daily Dose

Your doctor will prescribe the daily dosage of Forglyn Respicap based on the severity of your condition and how you respond to the treatment. Always follow their instructions carefully.

Over Dose

Exceeding the prescribed dosage of Forglyn Respicap may cause symptoms like increased heart rate, shaking, headaches, and nausea. If you experience these symptoms, inform your doctor straight away.

Missed Dose

If you forget to take a dose of Forglyn Respicap, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one.

Keep Forglyn Respicap at a cool room temperature, ideally between 20°C and 25°C.
Avoid exposing the medicine to excessive heat, light, or moisture.
Store in a dry place, ensuring the container is tightly closed after each use.
Always keep this medicine out of reach of children.
Ensure you use Forglyn Respicap before its expiry date.

If you're managing chronic obstructive pulmonary disease (COPD) with Forglyn Respicap, try to avoid respiratory irritants like smoke and dust in your environment. These can worsen breathing problems.
Maintain a balanced diet rich in fruits and vegetables. They help strengthen your immune system and may reduce COPD symptoms. Always remember to consult your doctor before making any significant lifestyle or dietary changes.

Fact Box

Drug Category	LABA and LAMA
Therapeutic Category	Bronchodilator
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Chronic obstructive pulmonary disease, Chronic bronchitis, Emphysema

What Is Forglyn Respicap?

Forglyn Respicap is a medicine containing formoterol fumarate and glycopyrrolate, intended for managing chronic obstructive pulmonary disease (COPD).

How Does Forglyn Respicap Work?

It contains two active ingredients. Formoterol fumarate relaxes the bronchial muscles, and glycopyrrolate inhibits acetylcholine, both resulting in improved airflow.

How Should I Use Forglyn Respicap?

Inhale the contents of Forglyn Respicap in the dosage prescribed by your doctor via inhaler device. Remember that the capsules should not be swallowed but inhaled.

Can I Use Forglyn Respicap for Asthma or Acute Bronchospasm?

No, Forglyn Respicap is not indicated for managing acute bronchospasm or asthma. Please consult your doctor for appropriate medication.

What Are the Side Effects of Forglyn Respicap?

Common side effects include upper respiratory tract infections, dry mouth, headaches, cough, dizziness, and nausea. If symptoms persist, consult your doctor immediately.

Can I Take Other Medicines Alongside Forglyn Respicap?

Certain medications may interact with Forglyn Respicap; therefore, it's essential to inform your doctor about all medicines you are currently taking.

How Should I Store Forglyn Respicap?

Store the capsules at room temperature (20°C to 25°C) in a dry place protected from light and moisture. Keep the inhaler clean and dry.

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 5 years

MD Ayurveda

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

AstraZeneca. (2016). BEVESPI AEROSPHERE [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208294s000lbl.pdf
Pearl Therapeutics, & Wheeler, B. (2015). 505(b)(2) ASSESSMENT. In CENTER FOR DRUG EVALUATION AND RESEARCH. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2016/208294Orig1s000OtherR.pdf
Food and Drug Administration. (2024). Draft guidance on formoterol fumarate; glycopyrrolate [Draft Guidance]. https://www.accessdata.fda.gov/drugsatfda_docs/psg/PSG_208294.pdf
Glycopyrronium: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00986
Formoterol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00983

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