Flodart Plus 0405 Mg Capsule Pr 10

Flodart Plus Capsule 10

Aristo Pharmaceuticals Pvt.ltd

Strip of 10 Units

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MRP ~~₹215~~

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₹21.50/Units

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Composition

Dutasteride (0.5 Mg) + Tamsulosin (0.4 Mg)

Flodart Plus Capsule is primarily used to manage symptomatic benign prostatic hyperplasia (BPH) in adult men with enlarged prostate. This is a combination medicine that belongs to the class of 5α-reductase inhibitors and α1-adrenergic receptor antagonists.

Besides its main use in managing BPH, Flodart Plus Capsule also aids in easing difficulties with urination associated with prostate enlargement. It helps in reducing urinary frequency, urgency, and incomplete emptying of the bladder.

You should take this medicine orally as directed by your doctor. It is important to let your doctor know about any pre-existing conditions or ongoing medications before starting Flodart Plus Capsule. If you experience any side effects while on this medicine, notify your doctor immediately. To attain the desired results, it is crucial to continue taking the capsule for as long as your doctor advises.

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Flodart Plus Capsule is used to relieve symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH) in men. It helps make urination easier by relaxing the muscles in the prostate and bladder, and it reduces the hormone DHT, which contributes to prostate growth.

Directions for Use of Flodart Plus Capsule 10

Follow these instructions while taking Flodart Plus Capsule:

Swallow the capsule whole with a glass of water.
Do not chew or crush the capsule. It should be swallowed whole.
Take the capsule approximately 30 minutes after the same meal each day.
If you're unsure about anything related to your medication, don't hesitate to consult your doctor.

Flodart Plus Capsule is taken orally.

Flodart Plus Capsule may have the following common side effects:

Impotence
Decreased libido
Difficulty with ejaculation
Decreased semen volume
Breast enlargement or tenderness
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Flodart Plus Capsule . However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: Try to rise slowly from a seated or lying down position. This can help reduce the feeling of dizziness caused by sudden movement.
Difficulty with ejaculation: If you experience this issue, consider taking this medicine at night to help manage this effect.

Flodart Plus Capsule contains two active ingredients which work together to manage the symptoms of BPH:

Dutasteride (0.5 mg): This compound works by inhibiting an enzyme called 5α-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By lowering DHT levels in the prostate, dutasteride can gradually reduce the size of an enlarged prostate and improve urinary symptoms.
Tamsulosin (0.4 mg): This ingredient acts by selectively blocking α1-adrenergic receptors located in the smooth muscle tissues of the prostate and the bladder neck. This action relaxes these tissues, thereby reducing resistance to urine flow and relieving obstructive symptoms without affecting bladder contractility.

Together, these two components provide more rapid and pronounced symptomatic relief compared to either drug alone. However, it may take several months for maximum benefits to develop as the prostate gradually decreases in size.

Pregnancy

Not applicable as it is used in men.

Breastfeeding

Not applicable as it is used in men.

Alcohol

While taking Flodart Plus Capsule, it's recommended to avoid alcohol as it may worsen some side effects like dizziness. Always discuss with your doctor about your alcohol consumption.

Liver

Caution is advised while taking Flodart Plus Capsule if you have mild to moderate liver impairment. This medicine is not recommended for severe liver diseases. Discuss any liver problems with your doctor before starting this medication.

Kidney

If you have a history of kidney problems, it is advised to consult your doctor before starting Flodart Plus Capsule.

Using Machines & Driving

Since dizziness is a possible side effect of Flodart Plus Capsule, caution is advised while driving or operating heavy machinery. Avoid such activities if you feel dizzy after taking the medication.

Allergy

Flodart Plus Capsule shouldn't be used if you're allergic to dutasteride, tamsulosin, or any other ingredients in the formulation. Always inform your doctor about any allergies before starting the medication.

Children

Flodart Plus Capsule should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

For older patients, it is advisable to use Flodart Plus Capsule under medical supervision due to an increased susceptibility to side effects. This is especially important for those above 70 years of age who may also have liver and kidney concerns. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Flodart Plus Capsule interacts with the following medicines:

Warfarin: This medicine's levels could be affected by tamsulosin, which might require closer monitoring of your INR values.
Alpha-blockers: Other alpha-blockers like doxazosin and prazosin can have additive blood pressure lowering effects when taken with Flodart Plus Capsule.
CYP3A4 and CYP2D6 inhibitors: Medicines like ketoconazole, ritonavir, clarithromycin, and terbinafine can increase levels of dutasteride and tamsulosin in your body.
PDE-5 inhibitors: Medicines such as sildenafil and tadalafil used for erectile dysfunction may amplify the blood pressure-lowering effects of tamsulosin.

Drug-Food Interactions

Grapefruit juice: Consuming grapefruit juice while taking this medicine could increase drug concentration in the body.

Drug-Disease Interactions

Flodart Plus Capsule interacts with the following diseases:

Liver disease: If you have severe liver problems, you should avoid taking Flodart Plus Capsule as dutasteride is extensively metabolised in the liver.
Kidney disease: You should exercise caution if you have serious kidney impairment as this medicine's safety and efficacy have not been established in patients with severe renal impairment.

Daily Dose

Your doctor will prescribe the daily dose of Flodart Plus Capsule. This dosage may vary depending on the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Flodart Plus Capsule, you might experience common side effects like dizziness or nausea in a more pronounced manner. If these symptoms persist or become severe, inform your doctor.

Missed Dose

If you forget to take your dose of Flodart Plus Capsule, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose to compensate for a missed one, unless advised by your doctor.

Store Flodart Plus Capsule at room temperature, preferably below 30°C.
Keep it protected from light and moisture to maintain its effectiveness.
Ensure the medicine is kept out of reach of children.
Always check the expiry date on the package before use.

Stay well-hydrated: As Flodart Plus Capsule is used to manage symptoms of an enlarged prostate, it is beneficial for you to drink plenty of water each day. This helps keep your urinary system functioning smoothly.
Practice pelvic floor exercises: These exercises can help strengthen your bladder muscles, improving your control over urination and relieving urinary symptoms associated with an enlarged prostate. Be sure to consult your doctor for proper instructions on how to perform these exercises.

Fact Box

Drug Category	5α-reductase Inhibitor, α1-Adrenergic Antagonist
Therapeutic Category	Anti-BPH Medication
Available Dosage Types	Capsule ER
Habit Forming	No
Ailment	Benign Prostatic Hyperplasia

What is Flodart Plus Capsule used for?

It is used to manage symptoms of benign prostatic hyperplasia (BPH), which is an enlarged prostate in adult men.

How does Flodart Plus Capsule work?

It contains tamsulosin that relaxes muscles in the prostate and dutasteride that reduces the hormone causing prostate growth.

How should I take Flodart Plus Capsule?

Take one capsule orally daily, around 30 minutes after the same meal each day, without chewing or crushing it.

When can I expect to see improvements from Flodart Plus Capsule?

Initial improvement may be noticed within 1-2 weeks but maximum effects typically show after 3-6 months of continuous use.

Can I stop taking Flodart Plus Capsule once my symptoms improve?

No, it is for long-term management of BPH. Symptoms may recur if you stop. Consult your doctor before stopping the medication.

Can Flodart Plus Capsule prevent prostate cancer?

No, it is not approved for preventing prostate cancer. Regular screening for prostate cancer should continue while taking this medicine.

What should I do if I experience side effects from Flodart Plus Capsule?

Inform your doctor about any adverse effects. Serious reactions like allergies or prolonged erections need immediate medical attention.

Last Updated On 09 Oct. 2024 | 6:20PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

References

Dutasteride and TAMSULOSIN hydrochloride- dutasteride and tamsulosin hydrochloride capsules capsule. (n.d.). DailyMed. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8c6031b3-b6a8-4ec7-b0d3-286f50d29353
GlaxoSmithKline. (2020, December). JALYN (dutasteride and tamsulosin hydrochloride) capsules. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022460s011lbl.pdf
Dimitropoulos, K., & Gravas, S. (2015). Fixed-dose combination therapy with dutasteride and tamsulosin in the management of benign prostatic hyperplasia. Therapeutic Advances in Urology, 8(1), 19-28. https://doi.org/10.1177/1756287215607419

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