Fibator Ez 1016010 Mg Tablet 10

Fibator Ez Tablet 10

Q: What is Fibator EZ Tablet used for?

It's used to manage high cholesterol and triglyceride levels, helping to decrease LDL ("bad" cholesterol) and increase HDL ("good" cholesterol).

Q: Can I take Fibator EZ Tablet without food?

You must take the medicine as directed by your doctor.

Q: What should I do if I miss a dose of Fibator EZ Tablet?

Take the missed dose as soon as you remember. But if it's close to the time for your next dose, skip the missed one.

Q: Can Fibator EZ Tablet cause muscle pain?

It might cause muscle pain and weakness in rare cases. If you experience unexplained muscle pain, consult your doctor immediately.

Q: How long does it take for Fibator EZ Tablet to work?

You may see a significant reduction in cholesterol levels within two weeks, but the maximum effect may take 4-6 weeks.

Q: Can I drink grapefruit juice while taking Fibator EZ Tablet?

It's best to avoid large quantities of grapefruit juice as it can increase the risk of side effects by interfering with the medicine's breakdown.

Q: Are there any specific precautions I should follow while taking Fibator EZ Tablet?

Yes, monitor any potential side effects involving the liver, muscles, and gallbladder. Also, concomitant use should be avoided with strong CYP3A4 inhibitors.

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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MRP ~~₹290~~

₹237.8

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Composition

Atorvastatin (10 Mg) + Ezetimibe (10 Mg) + Fenofibrate (160 Mg)

Fibator EZ Tablet is a medication primarily used to manage high cholesterol and triglyceride levels. This combination medicine belongs to the classes of statins, cholesterol absorption inhibitors, and fibrates.

In addition to its main use, this medicine can help increase HDL, or "good" cholesterol, in patients with primary hypercholesterolemia or mixed dyslipidemia. It can reduce triglycerides in patients with hypertriglyceridemia and lower total cholesterol and LDL in patients with homozygous familial hypercholesterolemia (HoFH).

This medicine should be taken orally as directed by your doctor. Always consult your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Fibator EZ Tablet is utilised for the following conditions:

Management of high levels of total cholesterol.
Regulation of LDL cholesterol, also known as bad cholesterol.
Control of elevated triglycerides, a type of fat found in the blood.
Elevation of HDL cholesterol, also known as good cholesterol.
Management of primary hypercholesterolemia or mixed dyslipidemia, conditions characterised by abnormally high cholesterol levels.
Regulating high triglyceride levels in patients with hypertriglyceridemia.
Management of Homozygous Familial Hypercholesterolemia (HoFH), a genetic disorder that leads to extremely high cholesterol levels.

Directions for Use of Fibator Ez Tablet 10

You can follow these instructions when taking Fibator EZ Tablet:

This medicine should be swallowed whole with a glass of water.
Avoid crushing, chewing or breaking the tablet.
It's crucial not to exceed the recommended dose without consulting your doctor.
Remember, it's important not to stop taking this medicine without speaking to your doctor first.

Fibator EZ Tablet is taken orally.

Fibator EZ Tablet may have the following common side effects:

Nasopharyngitis: This is an inflammation of the nose and throat that you might recognise as a common cold.
Arthralgia: This refers to joint pain, which can occur in any part of your body where two or more bones meet.
Diarrhoea
Pain in extremity
Urinary tract infection
Dyspepsia: This medicine might cause indigestion or bloating.
Nausea
Musculoskeletal pain: This is pain affecting your muscles, ligaments, tendons, and bones.
Muscle spasms
Myalgia: This is muscle ache or muscle pain.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Fibator EZ Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dyspepsia: If you have indigestion, take this medicine after meals to lessen this effect.
Pain in extremities: If you experience pain in your arms or legs during the day, consider taking this medicine at night.

Fibator EZ Tablet contains three active components, each contributing to its effect:

Fenofibrate (160 mg): As a fibrate, it activates a receptor called Peroxisome Proliferator-Activated Receptor α (PPARα). This action increases the breakdown of triglyceride-rich particles and alters LDL composition, making the LDL particles larger and more easily cleared from the body.
Atorvastatin (10 mg): This statin inhibits HMG-CoA reductase, an enzyme involved in cholesterol production within the body. Doing so enhances the uptake and breakdown of LDL or "bad" cholesterol and reduces its production.
Ezetimibe (10 mg): This component works within the small intestine to inhibit cholesterol absorption. This reduction in intestinal cholesterol results in lower liver cholesterol stores and increased cholesterol clearance from the blood.

Pregnancy

Fibator EZ Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, ensure to discuss this with your doctor before starting this medicine.

Breastfeeding

Fibator EZ Tablet is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Consumption of alcohol may potentially interfere with the effectiveness of Fibator EZ Tablet. It is best to consult your doctor for guidance about consuming alcohol while taking this medicine.

Liver

Caution is advised while taking Fibator EZ Tablet if you have mild to moderate liver impairment. It's not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Fibator EZ Tablet.

Kidney

Fibator EZ Tablet is not recommended if you have severe kidney impairment. Caution is advised if you have a history of kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

While generally safe, some individuals may experience side effects that could affect their ability to drive or operate machinery. Avoid driving or operating heavy machinery if you experience dizziness, drowsiness, fatigue, or visual disturbances after taking Fibator EZ Tablet.

Allergy

If you are known to have hypersensitivity or allergy to atorvastatin, ezetimibe, fenofibrate or any other components of Fibator EZ Tablet, it's best not to take this medication. Always let your doctor know about any allergies before starting a new medicine.

Children

Caution is advised while giving Fibator EZ Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Fibator EZ Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if you are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Fibator EZ Tablet interacts with the following medicines:

Strong inhibitors of CYP3A4: Concomitant use with this medicine is contraindicated due to an increased risk of side effects. Examples include medicines like ketoconazole and ritonavir.
Immunosuppressants: The combination of this medicine with immunosuppressants like cyclosporine can increase the exposure and risk of muscle pain or weakness (myopathy/rhabdomyolysis).
Statins: Medicines like gemfibrozil can increase the risk of muscle pain (myopathy) when taken with Fibator EZ Tablet and should be avoided.
Anticoagulants: Fenofibrate in Fibator EZ Tablet may potentiate coumarin-type anticoagulants, requiring more frequent monitoring of clotting time (INR).
Bile acid sequestrants: Ezetimibe should be taken ≥2 hours before or ≥4 hours after bile acid sequestrants to prevent interference with absorption.

Drug-Food Interactions

In terms of food interactions, avoid consuming large quantities of grapefruit juice (>1.2 litres/day), as it can increase the risk of side effects by inhibiting the breakdown of atorvastatin.

Drug-Disease Interactions

Fibator EZ Tablet interacts with the following diseases:

Active liver disease or unexplained persistent elevations of serum transaminases: This medicine could exacerbate these conditions and hence should be used cautiously.
Gallbladder disease: Fenofibrate in Fibator EZ Tablet may increase cholesterol excretion into the bile, potentially leading to gallstones.
Severe renal impairment (eGFR <30 mL/min/1.73 m2): This medicine should be used cautiously in patients with severe kidney disease.

Daily Dose

The daily dose of Fibator EZ Tablet is as prescribed by your doctor, taking into account factors such as the severity of the condition and response to medication. Always adhere to the recommended dosage and seek your doctor's advice before making any changes. For further details, read the package insert.

Over Dose

Overdosing on Fibator EZ Tablet could lead to side effects like nausea and muscle pain. If you suspect an overdose, don't panic, but inform your doctor about it.

Missed Dose

If you forget to take your regular dose of Fibator EZ Tablet, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and resume your normal schedule. Never increase your dosage without consulting your doctor.

Store Fibator EZ Tablet at room temperature.
Keep it in a dry place, shielded from direct light and moisture.
Make sure to keep this medicine out of the reach and sight of children.
It's critical to use the product before the expiry date indicated on the packaging.

Since Fibator EZ Tablet helps in the management of high cholesterol and triglyceride levels, consider incorporating a low-fat, low-cholesterol diet into your lifestyle. This means limiting foods high in saturated fats like fatty meats and full-fat dairy products.
Regular physical activity can also help manage your cholesterol levels. Aim for at least 30 minutes of moderate-intensity exercise, like brisk walking or cycling, most days of the week. Always consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	HMG CoA Reductase Inhibitor, Cholesterol Absorption Inhibitor, PPARα Activator
Therapeutic Category	Lipid Lowering Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypercholesterolemia, Hypertriglyceridemia, Mixed Dyslipidemia

What is Fibator EZ Tablet used for?

It's used to manage high cholesterol and triglyceride levels, helping to decrease LDL ("bad" cholesterol) and increase HDL ("good" cholesterol).

Can I take Fibator EZ Tablet without food?

You must take the medicine as directed by your doctor.

What should I do if I miss a dose of Fibator EZ Tablet?

Take the missed dose as soon as you remember. But if it's close to the time for your next dose, skip the missed one.

Can Fibator EZ Tablet cause muscle pain?

It might cause muscle pain and weakness in rare cases. If you experience unexplained muscle pain, consult your doctor immediately.

How long does it take for Fibator EZ Tablet to work?

You may see a significant reduction in cholesterol levels within two weeks, but the maximum effect may take 4-6 weeks.

Can I drink grapefruit juice while taking Fibator EZ Tablet?

It's best to avoid large quantities of grapefruit juice as it can increase the risk of side effects by interfering with the medicine's breakdown.

Are there any specific precautions I should follow while taking Fibator EZ Tablet?

Yes, monitor any potential side effects involving the liver, muscles, and gallbladder. Also, concomitant use should be avoided with strong CYP3A4 inhibitors.

Last Updated On 12 Oct. 2024 | 3:12PM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

References

U.S. National Library of Medicine. (2022). Atorvastatin. MedlinePlus. https://medlineplus.gov/druginfo/meds/a600045.html
U.S. National Library of Medicine. (2022). Ezetimibe. MedlinePlus. https://medlineplus.gov/druginfo/meds/a603015.html
U.S. National Library of Medicine. (2022). Fenofibrate. MedlinePlus. https://medlineplus.gov/druginfo/meds/a601052.html
U.S. Food and Drug Administration. (2009). Label: Atorvastatin. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s057lbl.pdf
U.S. Food and Drug Administration. (2006). Label: Ezetimibe. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021445s014lbl.pdf
U.S. Food and Drug Administration. (2008). Label: Fenofibrate. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021350s008lbl.pdf

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