Exenta 25 Mg Tablet 10

Exenta 25 Tablet 10

Alembic Ltd

Strip of 10 Units

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₹221.85

₹27.06/Units

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Composition

Eplerenone (25 Mg)

Strength:

50 MG 25 MG

Exenta 25 Tablet is commonly used to manage hypertension or high blood pressure. It belongs to a group of medicines known as selective aldosterone receptor antagonists.

In addition to managing hypertension, this medication is also used to improve survival in patients who have suffered from a heart attack and are exhibiting signs of congestive heart failure. This specific use applies to stable patients showing left ventricular systolic dysfunction, where the ejection fraction is less or equal to 40%.

Before taking this medicine, consult your doctor to determine the appropriate dosage and frequency. Inform your doctor about any health conditions you have or any other medicines you are currently taking before starting this medicine. If you notice any side effects while using this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor to achieve the best results.

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Exenta 25 Tablet is used for the following:

Decreasing high blood pressure: Also known as hypertension, this condition can lead to serious heart complications if not managed.
Enhancing survival rates in heart failure patients after a heart attack: Specifically, it's used in patients who have left ventricular systolic dysfunction and clinical evidence of congestive heart failure.

Directions for Use of Exenta 25 Tablet 10

Follow these instructions while taking Exenta 25 Tablet:

Swallow the tablet whole with water.
Avoid crushing or chewing it.
Stick to the prescribed dosage. Do not take more without consulting your doctor.
Never stop taking this medicine without speaking to your doctor first. Even if you feel well, continue taking your medicine as directed.

Exenta 25 Tablet is taken orally.

Exenta 25 Tablet could cause the following side effects:

Diarrhoea
Dizziness
Hypertension: This refers to high blood pressure.
Nausea
Headache
Fatigue
Cough
Hyperkalemia: This is a condition where the potassium level in your blood is higher than normal.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Exenta 25 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are two tips for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Hyperkalaemia: If you experience symptoms like muscle weakness or fatigue, it might be due to high potassium levels. Consult your doctor immediately.

Exenta 25 Tablet contains Eplerenone (25 mg), which works on your body in the following ways:

Blocks Aldosterone: Eplerenone works by selectively blocking the binding of aldosterone, a hormone that helps regulate blood pressure and fluid balance.
Reduces Sodium Retention: By blocking aldosterone's effects, Eplerenone reduces sodium retention in your body.
Increases Potassium Retention: Eplerenone reduces sodium retention and increases potassium retention, which helps maintain a healthy balance of electrolytes.
Lowers Blood Pressure: These effects help lower your blood pressure, which is beneficial in managing hypertension and improving survival in heart failure patients post-myocardial infarction.

Pregnancy

Exenta 25 Tablet is not recommended if you are pregnant. This medicine may harm the developing baby. Consult your doctor before taking this medicine.

Breastfeeding

The effects of Exenta 25 Tablet on breastfeeding women are unknown. It's better to consult your doctor before taking this medication.

Alcohol

Caution is advised while consuming alcohol when taking Exenta 25 Tablet. It may alter the effectiveness of the medicine. Consult your doctor for advice.

Liver

If you have liver-related issues, discuss this with your doctor before starting treatment with Exenta 25 Tablet, as it may affect liver function.

Kidney

Caution is advised for individuals with kidney health concerns. It would be wise to consult your doctor before starting this medication.

Using Machines & Driving

While taking Exenta 25 Tablet, if you experience dizziness or fatigue, avoid driving or operating heavy machinery.

Allergy

If you are allergic to eplerenone or any other ingredients in Exenta 25 Tablet, refrain from using this medicine and consult your doctor for alternatives.

Children

Caution is advised while giving Exenta 25 Tablet to children under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Exenta 25 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Exenta 25 Tablet interacts with the following medicines:

CYP3A4 Inhibitors: Medicines like ketoconazole or ritonavir can increase the level of Exenta 25 Tablet in your body, making side effects more likely.
ACE Inhibitors and ARBs: When taken with Exenta 25 Tablet, medicines such as lisinopril or losartan increase the risk of high potassium levels in your blood.
Potassium-Sparing Diuretics: Medicines like spironolactone or amiloride, taken alongside Exenta 25 Tablet, can also increase your blood potassium levels.
NSAIDs: Medicines like ibuprofen or naproxen may reduce the blood pressure-lowering effect of Exenta 25 Tablet and increase the risk of kidney problems.

Drug-Food Interactions

Certain foods can interact with Exenta 25 Tablet:

High Potassium Foods: Foods rich in potassium, such as bananas and spinach, can increase your blood potassium levels when consumed while taking this medicine.

Drug-Disease Interactions

Exenta 25 Tablet interacts with the following diseases:

Kidney Disease: If you have kidney disease, this medicine could cause further kidney damage, and you may be more susceptible to high potassium levels.
Diabetes: If you have Type 2 diabetes with microalbuminuria (a condition where a protein called albumin leaks into your urine), Exenta 25 Tablet could worsen your condition.

Daily Dose

Remember, it's vital to take Exenta 25 Tablet as prescribed by your doctor. The dosage can vary based on factors like the severity of your condition and how you respond to the medicine. Don't increase or decrease the dosage without consulting your doctor.

Over Dose

Taking more than the prescribed dose of Exenta 25 Tablet may lead to side effects such as dizziness, a feeling of nausea, or an increase in blood pressure. If you suspect an overdose, inform your doctor.

Missed Dose

If you forget to take dose of Exenta 25 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Exenta 25 Tablet at a temperature not exceeding 30°C.
Keep the medicine protected from light and moisture.
Keep away from children's reach.
Use this medicine before the expiry date mentioned on the pack.

If you're prescribed Exenta 25 Tablet for high blood pressure, try to reduce your salt intake. Too much salt can make your body hold water, raising your blood pressure.
For those managing heart failure after a heart attack, regular light exercise like walking or cycling helps strengthen the heart muscle. However, always consult your doctor before starting any new exercise routine.

Fact Box

Drug Category	Aldosterone Receptor Antagonist
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Heart Failure Post-Myocardial Infarction, Hypertension

What is Exenta 25 Tablet used for?

Exenta 25 Tablet is typically prescribed to manage hypertension (high blood pressure) and to enhance survival rates in heart failure patients after a heart attack.

How does Exenta 25 Tablet work?

The active ingredient, Eplerenone, blocks a hormone called aldosterone, which helps reduce salt retention, increase potassium retention, and hence lower blood pressure.

What should I do if I miss a dose of Exenta 25 Tablet?

Take the missed dose as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue your regular schedule.

Can I take Exenta 25 Tablet while pregnant or breastfeeding?

Exenta 25 Tablet may harm the foetus if taken during pregnancy. It's unknown if eplerenone is excreted in breast milk. Please consult your doctor first.

How long does it take for Exenta 25 Tablet to start working?

The onset of action varies depending on your condition. For high blood pressure, you may see changes within two weeks and maximum effect by four weeks.

Can I stop taking Exenta 25 Tablet if my blood pressure normalises or my heart failure symptoms improve?

Do not stop taking Exenta 25 Tablet without consulting your doctor, even if you feel better, as this could worsen your condition.

Can I take other medications while using Exenta 25 Tablet?

Some medicines can interact with Exenta 25 Tablet and cause side effects. Always inform your doctor about any other medications you're taking.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

References

NHS. (n.d.). Eplerenone. NHS. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/eplerenone/
U.S. Food and Drug Administration. (2016). Drug Approval Package: Inspra (Eplerenone) NDA #021437. U.S. Food and Drug Administration. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021437s013lbl.pdf
Eplerenone: MedlinePlus drug information. (2024, July 20). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a603004.html
Eplerenone. (2024, October 22). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00700
DailyMed. Eplerenone tablet. (n.d.). U. S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e2a51c12-bdc2-4b3b-8e9e-bf363c2817ed

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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