Cosvate Gm Cream 25 Gm

Cosvate GM ++ Cream 25gm

Eris Oaknet Healthcare Pvt Ltd

TUBE of 25 GM
TUBE of 20 GM

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MRP ~~₹92.45~~

₹75.81

₹3.70/GM

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Prescription required for this medicine

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Composition

Clobetasol Propionate (0.05 %) + Miconazole (2 %) + Neomycin (0.5 %)

Cosvate-GM ++ Cream is designed to manage various skin infections caused by bacteria and fungi. It belongs to a group of medicines known as combination creams, which contain different active ingredients that work together to combat infections.

In addition to its primary use, this cream also serves a significant role in managing inflammatory skin conditions like eczema, dermatitis, and psoriasis where secondary infections are a risk. It aids in reducing symptoms such as redness, swelling, and itching associated with these conditions.

Before starting this medicine, it’s important that you consult your doctor who will advise the right dosage and frequency for you. If you have any pre-existing medical conditions or are on other medications, do inform your doctor. Any side effects experienced during the course of taking this medicine should be reported promptly to your doctor. Ensure you continue using the cream for the duration prescribed by your doctor for best results.

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Cosvate-GM ++ Cream is used for managing the following conditions:

Resistant dermatoses with secondary bacterial or fungal infection
Inflammatory skin conditions like eczema
Dermatitis affected by susceptible bacteria or fungi
Psoriasis prone to secondary infections

Directions for Use of Cosvate GM ++ Cream 25gm

To use Cosvate-GM ++ Cream, follow these steps:

Clean and dry the skin area before application.
Apply a thin layer of the cream to the affected areas.
Use your fingertip or a clean cotton bud to gently spread the cream.
Wash your hands before and after applying, unless your hands are the treatment area.
For specific advice on how to use this medicine, consult your doctor.

Cosvate-GM ++ Cream is applied topically.

Side Effects of Cosvate GM ++ Cream 25gm

Cosvate-GM ++ Cream may have the following side effects:

Burning Sensation
Itching
Skin Irritation
Dryness
Redness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Cosvate-GM ++ Cream. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines:

Burning Sensation: If this happens, try applying a smaller amount of cream next time; too much at once can sometimes cause a burning sensation.
Dryness: If you notice dry skin after applying the cream, try using a gentle, unscented moisturiser on your skin before applying this cream.

Cosvate-GM ++ Cream consists of three active components each contributing towards combating skin infections:

Clobetasol Propionate (0.05%): This is a potent corticosteroid with anti-inflammatory, antipruritic (anti-itching), and vasoconstrictive (narrowing blood vessels) properties. It works by inhibiting the release of substances in the body that cause inflammation and reducing accumulation of leukocytes (white blood cells) at the affected site.
Miconazole (2%): This component is an antifungal agent which disrupts the synthesis of fungal cell membranes. It achieves this by inhibiting an enzyme known as 14-alpha-demethylase which is vital for fungal growth and proliferation.
Neomycin (0.5%): Classified as an aminoglycoside antibiotic, neomycin blocks bacterial protein synthesis leading to production of non-functional proteins and eventually bacterial cell death. It does so by binding to a part of the bacteria known as the 30S ribosomal subunit.

Pregnancy

Cosvate-GM ++ Cream is contraindicated during pregnancy unless necessary and under medical guidance. If you are pregnant or planning to conceive, ensure to discuss this with your doctor before using this medicine.

Breastfeeding

Breastfeeding women should use Cosvate-GM ++ Cream with caution and only under doctor's supervision. Understand the potential risks and benefits before using this cream.

Alcohol

Interactions between alcohol and Cosvate-GM ++ Cream are rare as it is a topical product. However, it's always wise to discuss any alcohol consumption with your doctor.

Liver

If you have any liver-related concerns, consult your doctor before using this cream.

Kidney

If you have a history of kidney problems, it's best to discuss it with your doctor before using this cream.

Using Machines & Driving

There's no adverse effect of Cosvate-GM ++ Cream on your ability to operate heavy machinery or drive. However, if you experience any side effects that might affect your alertness or concentration, avoid such activities and consult your doctor.

Allergy

If you're allergic to clobetasol propionate, miconazole, neomycin or any other ingredients in Cosvate-GM ++ Cream , do not use it. Always check the product packaging for a full list of ingredients.

Children

Cosvate-GM ++ Cream should be used with caution in children above 12 years of age. Always consult your doctor before giving any medication to a child.

Older Patients

Older patients should use Cosvate-GM ++ Cream under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status and any pre-existing conditions.

Interactions of Cosvate GM ++ Cream 25gm

Drug-Drug Interactions

Cosvate-GM ++ Cream interacts with the following medicines:

Topical Corticosteroids: Co-application of other topical steroids, such as hydrocortisone or betamethasone, with this cream, can increase the risk of side effects like skin thinning or irritation.
Immunosuppressants: Using medications like tacrolimus or pimecrolimus on the same skin area as this medicine can enhance systemic absorption of the cream's ingredients, potentially leading to increased side effects.

Drug-Food Interactions

Cosvate-GM ++ Cream, being a topical medication, does not interact with any foods or drinks.

Drug-Disease Interactions

Liver Disease: As neomycin, one of the components in Cosvate-GM ++ Cream, is metabolised by the liver, patients with liver disease may experience altered drug metabolism and excretion.
Skin Conditions: Patients with certain skin conditions like acne, rosacea, or perioral dermatitis should avoid using this cream as it can exacerbate these conditions.
Wound Healing: Open wounds or broken skin can increase systemic absorption of the active ingredients in Cosvate-GM ++ Cream, which might lead to more pronounced side effects.

Daily Dose

The daily dosage of Cosvate-GM ++ Cream should be as guided by your doctor. The amount you use may vary based on factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you accidentally apply too much Cosvate-GM ++ Cream, don't panic. You might experience some common side effects like mild skin irritation. However, if these persist or worsen, inform your doctor.

Missed Dose

If you forget to apply Cosvate-GM ++ Cream at the scheduled time, do it as soon as you remember. If it's nearly time for your next application, skip the missed one and continue with your usual routine. Never boost your dosage without discussing it with your doctor first.

Store Cosvate-GM ++ Cream at room temperature, ideally between 15°C and 30°C.
Keep the cream in a tightly closed container to protect it from excessive moisture.
Avoid exposure to direct sunlight.
Always keep this medicine out of the reach of children, for safety reasons.
Ensure you use the cream before its expiry date for maximum effectiveness.

For skin conditions like eczema or dermatitis managed by Cosvate-GM ++ Cream, consider adding Omega-3 rich foods like fish and walnuts to your diet as they may help reduce inflammation and improve symptoms.
Regular exercise can improve blood circulation, which helps nourish your skin cells. Aim for at least 30 minutes of moderate exercise every day.

Fact Box

Drug Category	Corticosteroid, Antifungal, Antibiotic
Therapeutic Category	Anti-inflammatory
Available Dosage Types	Cream
Habit Forming	No
Ailment	Eczema, Dermatitis, Psoriasis

What is Cosvate-GM ++ Cream used for?

It is used to manage skin infections caused by bacteria and fungi, including conditions like eczema, dermatitis, and psoriasis.

How does Cosvate-GM ++ Cream work?

It combines the anti-inflammatory effect of clobetasol propionate, the antifungal action of miconazole, and neomycin's ability to combat bacterial infections.

How should I apply Cosvate-GM ++ Cream?

You should apply a thin layer to the affected skin areas twice daily or as directed by your doctor. Ensure your skin is clean and dry before application.

Can I use Cosvate-GM ++ Cream for acne or rosacea?

No, it's not recommended for acne, rosacea, or untreated skin infections. Always consult your doctor before using any new medication.

Are there any side effects of Cosvate-GM ++ Cream?

Yes, common side effects include burning sensation, itching, irritation, and dryness at the application site. If these persist or worsen, consult your doctor.

Can pregnant or breastfeeding women use Cosvate-GM ++ Cream?

Pregnant and breastfeeding women should only use this cream under medical guidance due to potential risks.

How should I store Cosvate-GM ++ Cream?

Store it at room temperature (15°C to 30°C) in a tightly closed container, away from direct sunlight and moisture. Keep out of reach of children.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

References

Clobetasol propionate. (n.d.). fda.gov. Retrieved May 27, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/Clobetasol%20Propionate_Emollient%20Cream%200.05_RLD%2075430_RC09-16.pdf
Clobetasol propionate. (n.d.). fda.gov. Retrieved May 27, 2024, from https://www.fda.gov/media/72973/download
Miconazole: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01110
Neomycin: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00994
Clobetasol propionate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01013

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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