Celrim 1000 Mg Injection 1

Celrim Injection 1

Biocon Ltd

Vial of 1 UNITS

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MRP ~~₹252.7~~

₹207.21

₹252.70/UNITS

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Composition

Cefepime (1000 Mg)

Celrim Injection 1 is used primarily to manage severe bacterial infections in different parts of the body. This injectable medicine is a member of the beta-lactam antibiotics, specifically known as cephalosporins.

Beyond its main use, this injection is additionally employed for managing serious infections in the skin, lungs, stomach, urinary tract, and blood. It's especially useful in critical medical scenarios where patients are hospitalised due to the intensity of their infections.

Before starting this medicine, you should inform your doctor about any existing health conditions or ongoing medications. If you experience any side effects while on this medication, notify your doctor immediately. It is important to continue administering this medicine for the entire duration prescribed by your doctor to ensure complete management of the infection.

Celrim Injection 1 is used for:

Managing severe bacterial infections of the skin
Controlling serious bacterial infections in the lungs
Combating severe bacterial infections in the stomach
Addressing serious bacterial infections in the urinary tract
Handling blood infections caused by bacteria

Directions for Use of Celrim Injection 1

Administer Celrim Injection 1 as follows:

The injection is administered intravenously by your doctor or nurse.
The injection could be administered slowly into a vein over 3-5 minutes or into a large muscle.
It's crucial to complete the prescribed course even if symptoms improve earlier.
Remember, skipping doses or stopping treatment prematurely may lead to inadequate control of the infection or the development of resistant bacteria.
Always consult your doctor for specific advice on how to use this medicine.

Celrim Injection 1 is administered intravenously or intramuscularly.

Celrim Injection 1 may have the following side effects:

Diarrhoea
Nausea
Vomiting
Abdominal Pain
Phlebitis: This is inflammation of a vein, often where the injection was administered.
Anaemia: A condition where your blood has fewer red blood cells than normal, causing tiredness and shortness of breath.
Thrombocytopaenia: This relates to a lower platelet count, which helps your blood clot.
Paresthesia: This term describes abnormal sensations like tingling or numbness.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Celrim Injection 1. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Diarrhoea: Try consuming sufficient fluids to replace the water lost through diarrhoea.
Nausea: If you feel nauseous, consider having smaller but more frequent meals instead of three large meals a day.

Celrim Injection 1 contains cefepime (1000 mg) which acts on your body via the following mechanisms:

Inhibiting Cell Wall Synthesis: Cefepime works by blocking essential proteins needed for developing and strengthening bacteria's cell walls.
Causing Bacterial Cell Death: By disrupting the integrity of bacterial cell walls, cefepime causes lysis (the breaking down) of bacterial cells leading to their death.
Stability Against Beta-Lactamase Enzymes: Unlike some other cephalosporins, cefepime can resist many beta-lactamase enzymes produced by resistant bacteria, which could otherwise neutralise antibiotic effects.

Pregnancy

It is advised to consult your doctor before using this medicine during pregnancy.

Breastfeeding

Small amounts of Celrim Injection 1 may pass into breast milk. Although it is generally considered safe for use during breastfeeding, it's best to discuss it with your doctor.

Alcohol

Caution is advised, and it is best to consult your doctor.

Liver

Celrim Injection 1 may cause transient elevations in liver enzymes. If you have existing liver conditions, consult your doctor before starting this medication.

Kidney

People with kidney issues need to exercise caution while using Celrim Injection 1s, as dose adjustments may be required. Your doctor will guide you on this based on your health status.

Using Machines & Driving

Celrim Injection 1 can cause dizziness, a side effect that could impair your ability to drive or operate machinery. It's advisable not to engage in such activities until you know how the medicine affects you.

Allergy

This medicine is not recommended if you have severe allergies to cefepime or other cephalosporins. If you have a history of penicillin allergy, use this medicine with caution.

Children

Caution is advised while giving Celrim Injection 1 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Cautious use of Celrim Injection 1 is advised in older patients, especially those above 70 years of age. They may be more susceptible to side effects and might also have liver and kidney conditions. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Celrim Injection 1 interacts with the following medicines:

Aminoglycosides: Medicines like gentamycin or amikacin may interact with Celrim Injection 1, increasing the risk of kidney damage (nephrotoxicity).
Loop Diuretics: When taken with Celrim Injection 1, diuretics like furosemide can enhance the risk of kidney damage.
Oral Anticoagulants: Medications like warfarin and heparin can have their blood-thinning effect increased by Celrim Injection 1.

Drug-Food Interactions

No specific food interactions have been reported for the Celrim Injection 1.

Drug-Disease Interactions

Celrim Injection 1 interacts with the following diseases:

Kidney Disease: Patients with kidney disease should exercise caution when using this medicine as it may exacerbate their condition and require dosage adjustments.
Severe Allergies: Patients with a history of severe allergies to cephalosporins or penicillin should use this medicine carefully due to potential hypersensitivity reactions.

Daily Dose

The daily dose of Celrim Injection 1 is to be administered as per your doctor's instructions. The dosage may vary based on factors such as the seriousness of your condition and your response to the treatment. Ensure you strictly follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

An overdose is highly unlikely for this medication as it is administered by a skilled healthcare professional.

Missed Dose

If you forget to have a dose of Celrim Injection 1 as scheduled, consult with your doctor for advice.

Store Celrim Injection 1 at room temperature.
Keep it protected from light, which can degrade the medication.
It's important to keep this medicine out of reach of children.
Always check the expiry date before use, making sure it hasn't passed.

Since Celrim Injection 1 is used to manage serious bacterial infections, maintaining good hygiene is crucial. This includes regular handwashing and avoiding close contact with people who are ill.
A balanced diet rich in vitamins and minerals can help support your immune system while you're recovering from an infection. Including plenty of fruits and vegetables in your meals can provide the nutrients your body needs to fight off bacteria.

Fact Box

Drug Category	Cell Wall Synthesis Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Skin Infections, Lung Infections, Blood Infections

What is Celrim Injection 1 used for?

Celrim Injection 1 is used to manage severe bacterial infections of the skin, lungs, stomach, urinary tract, and blood.

How does Celrim Injection 1 work?

The active ingredient in Celrim Injection 1, cefepime, works by inhibiting the synthesis of bacterial cell walls, causing the bacteria to die.

How is Celrim Injection 1 administered?

This injection is administered intravenously by a doctor, usually through a slow infusion over 30 minutes or directly into a vein or large muscle.

Can I stop taking Celrim Injection 1 if my symptoms improve?

No, you should complete the full course prescribed by your doctor to ensure all bacteria are killed and to prevent resistance.

What are some common side effects of Celrim Injection 1?

Common side effects include diarrhoea, nausea, vomiting, abdominal pain, rash, and headache. Always consult your doctor if these persist or worsen.

Can I take Celrim Injection 1 if I'm allergic to penicillin?

You should use Celrim Injection 1 cautiously if you have a history of penicillin allergy. Always inform your doctor about any known allergies before starting any medication.

Can I take other medications while on Celrim Injection 1?

Certain medications may interact with Celrim Injection 1 causing unwanted effects. Always inform your doctor about all medications you're currently taking before starting this medicine.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Bristol-Myers Squibb Company. (2000). MAXIPIME (Cefepime hydrochloride, USP) for injection. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050679s032lbl.pdf
DailyMed - CEFEPIME injection, powder, for solution. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e80c27e2-164d-4836-ba24-c160d75dc5d3
Cefepime: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01413
Cefepime injection: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a698021.html
O’Connor, A., Lopez, M. J., Patel, P., & Eranki, A. P. (2024, February 28). Cefepime. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK542232/

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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