Aquazide 125 Mg Tablet 10

Aquazide 12.5 Tablet 10

Sun Pharma Laboratories Ltd.

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Composition

Hydrochlorothiazide (12.5 Mg)

Strength:

25 MG 12.5 MG

Aquazide 12.5 Tablet is primarily used for managing hypertension, which is high blood pressure. It is a type of medicine known as a thiazide diuretic.

Apart from hypertension, this medicine also helps in reducing oedema. Edema is a condition where your body retains more water and salt than it should, causing swelling. This can occur due to various medical conditions such as heart failure, liver cirrhosis, chronic kidney disorders, or due to corticosteroid and estrogen therapy.

Before you start taking this medicine, it's important to consult your doctor about the right dosage and frequency for you. You should also inform your doctor about any pre-existing conditions or ongoing medications. If you experience any side effects while using this medicine, notify your doctor immediately. It's crucial to continue taking the medicine for the duration prescribed by your doctor for best results.

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Aquazide 12.5 Tablet is used for the following:

Managing high blood pressure: This medicine helps control hypertension, which can prevent heart attacks and strokes.
Reducing fluid accumulation in the body: It's effective in managing oedema or swelling caused by heart failure, liver cirrhosis, or kidney disorders.
Assisting in fluid management during corticosteroid therapy: This medication can help manage fluid retention that can occur with corticosteroid use.
Assisting in fluid management during estrogen therapy: It can manage fluid build-up that can happen while on estrogen therapy.

Directions for Use of Aquazide 12.5 Tablet 10

Follow these instructions while taking Aquazide 12.5 Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Take this medicine once daily, ideally in the morning, to avoid frequent urination at night.
Always take this medication as recommended by your doctor. If you have any doubts or questions, do not hesitate to consult your doctor.

Aquazide 12.5 Tablet is taken orally.

Aquazide 12.5 Tablet may cause the following common side effects:

Headache
Fatigue
Muscle cramps or weakness
Gastrointestinal disturbances: These could include nausea, vomiting, diarrhoea, or constipation.
Hyperuricemia and gout: This means there's an excess of uric acid in your blood, which can lead to gout a type of arthritis that causes sudden, severe attacks of pain and swelling in your joints.
Impotence

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Aquazide 12.5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Gastrointestinal disturbances: If you experience stomach upset after taking this medicine, try taking it with meals.
Muscle cramps or weakness: If these occur after taking this medicine, consider adjusting the timing; for example, you may want to take it at bedtime.

Aquazide 12.5 Tablet contains hydrochlorothiazide (12.5 mg), which works in the following ways:

Increases Urine Output: Hydrochlorothiazide increases the amount of salt and water that your body gets rid of through urine. This process is known as diuresis.
Lowers Blood Volume: By causing diuresis, hydrochlorothiazide reduces the volume of blood that your heart needs to pump, which in turn lowers blood pressure.
Decreases Fluid Retention: Hydrochlorothiazide works on your kidneys to block the reabsorption of sodium and chloride. This action reduces fluid retention in your body, helping to relieve oedema.

Pregnancy

Caution is advised while taking Aquazide 12.5 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Aquazide 12.5 Tablet should be taken with caution if you are breastfeeding. The decision to continue nursing or discontinue the medication should be made after discussing it with your doctor.

Alcohol

It's safe to consume alcohol while taking Aquazide 12.5 Tablet.

Liver

Thiazide diuretics like Aquazide 12.5 Tablet should be used cautiously in patients with liver impairment or progressive liver disease as it could worsen their condition. It is advisable to consult your doctor before starting this medicine.

Kidney

This medicine may precipitate azotemia in patients with severe renal disease. Caution is advised before using Aquazide 12.5 Tablet if you have a history of any kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

No specific precautions are mentioned regarding operating machinery or driving while using Aquazide 12.5 Tablet but if you experience side effects like dizziness, avoid such activities and consult your doctor.

Allergy

If you have a history of allergy or hypersensitivity reactions to hydrochlorothiazide, avoid using Aquazide 12.5 Tablet and consult your doctor.

Children

Aquazide 12.5 Tablet should not be given to children unless prescribed by a doctor due to limited data available on its use in paediatric patients.

Older Patients

Older patients should take Aquazide 12.5 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Aquazide 12.5 Tablet interacts with the following medicines:

NSAIDs: Medicines such as ibuprofen and naproxen can decrease the blood pressure-lowering effects of Aquazide 12.5 Tablet and increase the risk of kidney problems.
Alcohol, barbiturates, or narcotics: These substances may increase the chance of a sudden drop in blood pressure when getting up from a sitting or lying position.
Antidiabetic medicines: Medications like metformin might need a dosage adjustment due to Aquazide 12.5 Tablet's potential to raise blood sugar levels.
Medicines like cholestyramine and colestipol resins: These can reduce the absorption of Aquazide 12.5 Tablet in your body.
Corticosteroids, ACTH: These medications can enhance the loss of potassium in body fluids, leading to low potassium levels in your blood.
Mood Stabilising Medicines: You should generally avoid taking lithium with Aquazide 12.5 Tablet due to the risk of lithium toxicity.

Drug-Food Interactions

Aquazide 12.5 Tablet does not have any known interactions with food.

Drug-Disease Interactions

Aquazide 12.5 Tablet interacts with the following diseases:

Renal Impairment: Patients suffering from severe kidney disease should exercise caution as Aquazide 12.5 Tablet could worsen their condition.
Liver disease: Patients with liver disease should be careful as this medicine could exacerbate their condition.
Diabetes: If you have diabetes, your blood sugar levels might be affected by Aquazide 12.5 Tablet; therefore, frequent monitoring is necessary.

Daily Dose

You should take Aquazide 12.5 Tablet as prescribed by your doctor. The dosage depends on factors like the severity of your condition and how you respond to the medication. Always follow your doctor's instructions and don't exceed the prescribed dose without consulting them first.

Over Dose

If you accidentally take more than the prescribed dosage of Aquazide 12.5 Tablet, you may experience symptoms like dizziness, fatigue, and nausea. In such a scenario, it is advisable to inform your doctor who can give further guidance.

Missed Dose

If you forget to take Aquazide 12.5 Tablet at the scheduled time, take it as soon as you remember. However, if it's almost time for the next dose, just skip the missed one and continue with your regular dosage schedule. Don't increase your dosage without consulting your doctor.

Keep your Aquazide 12.5 Tablet at a cool room temperature between 15°C to 30°C.
The product should be stored in a dry place away from direct light and moisture.
Be sure to keep this medicine out of reach of children.
Always check the expiry date before using the Aquazide 12.5 Tablet.

If you're taking Aquazide 12.5 Tablet for high blood pressure, consider reducing your salt intake. Too much salt can cause your body to retain water, increasing blood pressure.
For those managing fluid retention (edema), limit your alcohol consumption. Alcohol can dehydrate you and exacerbate edema symptoms.

Fact Box

Drug Category	Thiazide Diuretic
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Oedema

What is Aquazide 12.5 Tablet used for?

Aquazide 12.5 Tablet is used to manage hypertension (high blood pressure) and edema (fluid retention) related to various medical conditions.

How does Aquazide 12.5 Tablet work?

This medicine works by increasing the amount of salt and water your body gets rid of through urine, which helps reduce blood pressure and fluid retention.

When should I take Aquazide 12.5 Tablet?

You should take Aquazide 12.5 Tablet as prescribed by your doctor.

Can I take Aquazide 12.5 Tablet if I have kidney problems?

If you have severe kidney problems, Aquazide 12.5 Tablet might not be suitable for you. You should consult your doctor before taking this medication.

What are some common side effects of Aquazide 12.5 Tablet?

Common side effects include dizziness, headache, fatigue, muscle cramps or weakness, gastrointestinal disturbances, and increased uric acid levels.

Can I drink alcohol while taking Aquazide 12.5 Tablet?

Alcohol can increase the risk of side effects from this medication like dizziness and changes in blood pressure. Consult your doctor before consuming alcohol.

Can pregnant women take Aquazide 12.5 Tablet?

Pregnant women should take this medication only if the potential benefit justifies the risk to the fetus, as advised by their doctor.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

References

U.S. National Library of Medicine. (2022). Hydrochlorothiazide. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682571.html
Herman, L. L., Weber, P., & Bashir, K. (2024). Hydrochlorothiazide. In StatPearls. StatPearls Publishing. Retrieved 15 October 2024, from
https://www.ncbi.nlm.nih.gov/books/NBK430766/
Hydrochlorothiazide. (n.d.). Retrieved 15 October 2024, from https://go.drugbank.com/drugs/DB00999
PubChem. (n.d.). Hydrochlorothiazide. Retrieved 15 October 2024, from https://pubchem.ncbi.nlm.nih.gov/compound/Hydrochlorothiazide
Ernst, M. E., & Fravel, M. A. (2022). Thiazide and the thiazide-like diuretics: Review of hydrochlorothiazide, chlorthalidone, and indapamide. American Journal of Hypertension, 35(7), 573–586. Retrieved 15 October 2024, from https://pubmed.ncbi.nlm.nih.gov/35404993/

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