Adilip 45 Mg Tablet Dr 10

Adilip 45 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹106.5~~

₹87.33

₹10.65/Units

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Composition

Fenofibrate (45 Mg)

Strength:

45 MG 135 MG

Adilip 45 Tablet is primarily used to manage high levels of cholesterol and triglycerides in the body. This medicine is a member of a group of medications known as fibrates.

In addition to managing LDL ("bad" cholesterol), total cholesterol and triglycerides, it also helps in increasing HDL ("good" cholesterol) levels. It is particularly useful for people dealing with conditions like severe hypertriglyceridemia (very high triglycerides) and mixed dyslipidemia.

You should take this medicine orally, as advised by your doctor. It's crucial to inform your doctor about any ongoing medications or pre-existing conditions before starting this medicine. If you notice any side effects while on this medication, notify your doctor immediately. Remember to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Adilip 45 Tablet is used for the following:

Managing high levels of LDL cholesterol, known as "bad" cholesterol
Reducing total cholesterol levels in your body
Decreasing high triglyceride levels, a type of fat in your blood
Increasing HDL cholesterol often referred to as "good" cholesterol
Managing severe hypertriglyceridemia, a condition where there are extremely high fat levels in your body

Directions for Use of Adilip 45 Tablet 10

Do not crush or chew the tablet.
Avoid taking more than your doctor has recommended.
If you plan to stop taking this medicine, do so only after consulting your doctor.

Adilip 45 Tablet is taken orally.

Adilip 45 Tablet may have the following common side effects:

Abnormal liver function tests
Increased serum creatinine: This refers to a slight increase in a waste product called creatinine in your blood, which is usually filtered out by your kidneys.
Digestive issues like nausea, diarrhoea, constipation, dyspepsia
Respiratory issues such as bronchitis, sinusitis, and rhinitis: These are conditions that affect your respiratory system, leading to symptoms like coughing, sneezing, runny nose, and difficulty breathing.
Musculoskeletal pain including arthralgia and myalgia: These are types of pain that can occur in your muscles (myalgia) or joints (arthralgia).
Headache and dizziness
Asthenia: This means you might feel unusually weak or tired.
Skin rash, pruritus (itching), urticaria (hives)

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolves on discontinuing the use of Adilip 45 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Digestive issues: If you experience digestive issues like nausea or dyspepsia, try taking Adilip 45 Tablet with food.
Asthenia: Consider taking this medicine at night if it makes you feel weak or tired during the day.

Adilip 45 Tablet contains fenofibrate (45 mg) and it works in your body as follows:

Activation of PPARα: Fenofibrate activates a specific nuclear receptor known as PPARα. This receptor helps regulate genes that are involved in managing fats in your body.
Breakdown of Triglyceride-rich Lipoproteins: Fenofibrate increases the breakdown of triglyceride-rich lipoproteins, reducing the levels of these fats in your blood.
Increase in HDL Synthesis: This medicine helps your body produce more HDL, or "good" cholesterol.
Reduction in VLDL Synthesis: Fenofibrate reduces the production of VLDL, a type of low-density lipoprotein that carries and deposits cholesterol in the tissues across your body.
Increased Clearance of LDL Particles: The medicine helps your body remove LDL, or "bad" cholesterol, more efficiently from your bloodstream.

Pregnancy

Adilip 45 Tablet should only be used during pregnancy if the potential benefits outweigh the possible risks. It is wise to consult your doctor before taking this medicine if you are pregnant or planning to conceive.

Breastfeeding

If you are breastfeeding, use caution while taking Adilip 45 Tablet. As it is unknown whether fenofibrate is excreted in human milk, you should either discontinue nursing or stop taking this medicine based on your doctor's advice.

Alcohol

It's recommended to avoid excessive alcohol consumption while taking Adilip 45 Tablet. Drinking too much alcohol can increase the risk of liver problems and other side effects.

Liver

If you have liver disease or persistent liver enzyme abnormalities, Adilip 45 Tablet is contraindicated. Regular monitoring of liver function is needed when using this medication.

Kidney

For those with severe kidney dysfunction, including dialysis patients, Adilip 45 Tablet is contraindicated. If you have mild to moderate kidney impairment, lower doses may be required.

Using Machines & Driving

There are no specific precautions for using machines or driving while taking Adilip 45 Tablet. However, if you experience dizziness or any other side effect that could impair your ability, consult your doctor immediately.

Allergy

If you have a known hypersensitivity to fenofibrate or any component of the formulation, use of Adilip 45 Tablet is contraindicated.

Children

Adilip 45 Tablet is not recommended for children as its safety and effectiveness haven't been established for pediatric patients. Always consult your doctor before giving any medicine to a child.

Older Patients

In older patients who may be more likely to have decreased kidney function, dose selection should be based on kidney function. It’s suggested to consult your doctor before using Adilip 45 Tablet if you are above 70 years of age.

Drug-Drug Interactions

Adilip 45 Tablet interacts with the following medicines:

Anticoagulants: Medicines like warfarin may have increased effects when taken with Adilip 45 Tablet, raising the risk of bleeding. Regular monitoring of coagulation is advised.
Immunosuppressants: Concurrent use with medicines such as cyclosporine may lead to an increased risk of kidney toxicity.
Bile acid sequestrants: Medicines like cholestyramine can reduce the absorption of fenofibrate. It's advisable to take Adilip 45 Tablet at least 1 hour before or 4-6 hours after taking a bile acid sequestrant.
Statins: The use of statins such as atorvastatin or rosuvastatin alongside Adilip 45 Tablet may increase the risk of muscle disorders like myopathy and rhabdomyolysis.

Drug-Food Interactions

Drug-Disease Interactions

Adilip 45 Tablet interacts with the following diseases:

Severe Kidney Dysfunction: Individuals with severe kidney problems, including those on dialysis, should avoid this medicine as it could worsen their condition.
Active Liver Disease: Those with active liver diseases should avoid Adilip 45 Tablet as it could exacerbate their condition. Regular liver function monitoring is necessary while on this medication.

Daily Dose

As per your doctor's advice, take your daily dose of Adilip 45 Tablet. The dosage might change based on factors like the severity of your condition and how you respond to the medication. Remember to stick to the dosage prescribed by your doctor and never exceed it without consulting them first.

Over Dose

If you accidentally take more than the prescribed dose of Adilip 45 Tablet, you may experience some common side effects such as nausea, headache, and muscle pain. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take a dose of Adilip 45 Tablet, take it as soon as you remember. But if it is already time for the next dose, skip the missed one and continue with your regular schedule. Don't increase your dosage without consulting your doctor.

Store Adilip 45 Tablet at room temperature, ideally below 25°C.
Keep the medicine in its original, tightly-closed container to protect it from light and moisture.
Always keep this medicine out of reach of children.
Make sure you use Adilip 45 Tablet before its expiry date.

Maintain a low-fat diet: Since Adilip 45 Tablet is used to manage high cholesterol, keeping your diet low in saturated and trans fats can help enhance the effectiveness of this medicine.
Regular exercise: A consistent exercise routine aids in increasing HDL ("good") cholesterol levels and reducing LDL ("bad") cholesterol levels, supporting the working of Adilip 45 Tablet.

Fact Box

Drug Category	PPARα Activator
Therapeutic Category	Lipid-Lowering Medication
Available Dosage Types	Tablet DR
Habit Forming	No
Ailment	Primary Hypercholesterolemia, Mixed Dyslipidemia, Severe Hypertriglyceridemia

What is Adilip 45 Tablet used for?

Adilip 45 Tablet is used to manage high levels of "bad" cholesterol, total cholesterol, and very high triglycerides, while raising "good" cholesterol levels.

How does Adilip 45 Tablet work?

It contains fenofibrate, which helps regulate fat metabolism. This leads to reduced synthesis of harmful fats and increased breakdown of triglyceride-rich particles.

How long does it take for Adilip 45 Tablet to show its effects?

The full lipid-lowering effect of this medicine is generally seen within two months, but maximum benefits may take up to four months.

Can I crush or chew Adilip 45 Tablet?

No, you should take the tablet whole with food to increase absorption. Do not crush or chew it.

Can I consume alcohol while taking Adilip 45 Tablet?

Avoid excessive alcohol intake while on this medicine, as it can increase the risk of liver problems and other side effects.

What if I miss a dose of Adilip 45 Tablet?

Take the missed dose as soon as you remember. If it's close to your next dose time, skip the missed one. Don't double up on doses.

What should I do if I experience muscle pain while taking Adilip 45 Tablet?

If you have unexplained muscle pain or weakness, especially if accompanied by fever or feeling unwell, contact your doctor immediately.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2018). [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021656s029lbl.pdf
Fenofibrate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01039
Sidhu, G., & Tripp, J. (2023, March 13). Fenofibrate. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559219/
Ezhov, M. V., & Arutyunov, G. P. (2023). Effectiveness and Safety of Fenofibrate in Routine Treatment of Patients with Hypertriglyceridemia and Metabolic Syndrome. Diseases, 11(4), 140. https://doi.org/10.3390/diseases11040140
Gunwal, D., Dutt, B., Choudhary, M., & Budhwar, V. (2021, August 5). A comprehensive review on the drug: fenofibrate. International Journal of Research in Pharmaceutical Sciences -. https://ijrps.com/index.php/home/article/view/238

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