Ursodeoxycholic Acid
HEPATOPROTECTIVEUses of Ursodeoxycholic Acid
- Ursodeoxycholic Acid (UDCA), also known as ursodiol, is used to treat primary biliary cirrhosis (PBC), dissolve small gallstones, and manage liver disease associated with cystic fibrosis in children. It has been used as a treatment for liver disease for over a century.
Side effects of Ursodeoxycholic Acid
- Diarrhoea
How Ursodeoxycholic Acid works
- Ursodeoxycholic Acid is a secondary bile acid with immunomodulant, cytoprotectant, and choleretic effects. It enhances the solubilisation of cholesterol in bile, reducing the formation and promoting the dissolution of gallstones. This mechanism is particularly relevant for small gallstones that may not be visible on X-ray.
- It exhibits hepatoprotective properties, protecting the liver cells from damage. It is particularly beneficial in conditions like primary biliary cirrhosis, contributing to the overall health and function of the liver.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Tablet
Age and Dose Restrictions
- It is intended for adults and children above 6 years.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Ursodeoxycholic Acid and patients with biliary obstructtion and liver impairment.
Other Medications To Avoid With This Medicine
- Avoid taking cholesterol lowering medications (colestyramine), immunosupressants (cyclosporin), antibiotics (ciprofloxacin), and oral contraceptives (ehinylestradiol). These medications may alter the safety and effectiveness of Ursodeoxycholic Acid.
Overdose and Missed Dose
- In case of accidental overdose, consult your doctor as overdose can cause diarrhoea. Strict adherence to the prescribed dose is essential.
- If you miss a dose of this medication, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Use In Driving And Operating Machinery
- It does not affect the ability to drive or operate machinery.
Use in Pregnancy and Lactation
- It is not recommended in pregnancy and breastfeeding.
Caution In Other Conditions
- Caution is advised in older adults and in liver diseases.
Special Dietary & Lifestyle Recommendation
- Include bell peppers, citrus fruits, leafy vegetables, and tomatoes in your daily meals. These are rich in essential nutrients.
- Integrate milk, fish, and low-fat dairy products into your diet to ensure an adequate calcium intake.
- Opt for plant-based protein sources like beans, nuts, lentils, tofu, and tempeh to contribute to gallbladder health.
- Consume foods rich in vitamins B and C, which benefit the gallbladder.
- Steer clear of high-fat, trans-fat, and processed foods that can harm gallbladder health.
- Eliminate white bread, white pasta, and sugars from your diet to support overall health.
- Minimize or avoid tobacco and alcohol consumption, as these habits can impact gallbladder function negatively.
Frequently asked questions
Does Ursodeoxycholic Acid cure fatty liver?
It is primarily prescribed for conditions like primary biliary cirrhosis and gallstone dissolution. Its effectiveness in treating fatty liver may vary, and it's crucial to consult a doctor for guidance on managing it.
Is Ursodeoxycholic Acid safe?
It is generally considered safe when used as a doctor prescribes. However, individual responses to medications may vary. It's important to discuss any concerns and side effects with your doctor.
How long can I take Ursodeoxycholic Acid?
The duration of use depends on the specific medical condition for which it is prescribed. Your doctor will determine the appropriate duration based on your case. Follow your doctor's instructions regarding the duration of treatment.
Is Ursodeoxycholic Acid good for constipation?
It is not typically used for treating constipation. If you are experiencing constipation, discussing this symptom with your doctor for appropriate management is advisable.
Can Ursodeoxycholic Acid dissolve gallstones?
Yes, it is often prescribed to dissolve certain types of gallstones, particularly cholesterol gallstones.Â
Ursodeoxycholic Acid in other salts
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