Thiopental Sodium

Expert Advice

Dosage Forms Available

• Thiopental Sodium is available as a powder that requires reconstitution to formulate an injectable solution.

• This medication is administered through the intravenous route by healthcare professionals trained in anaesthesia delivery.

Age and Dose Restrictions

• Thiopental Sodium is intended for use in adults as well as in children, though specific age restrictions apply, primarily depending on the health condition and medical supervision.

Contraindications

Thiopental Sodium is contraindicated in patients with:

• Known hypersensitivity to barbiturates

• Porphyria

• Severe cardiovascular disease

• Severe respiratory disease

• Myasthenia gravis

• Severe liver disease

Other Medications to Avoid

• Thiopental Sodium may interact with other central nervous system depressants (such as opioids and benzodiazepines), anticoagulants (like warfarin), corticosteroids (including prednisone), antihypertensives (such as amlodipine), and oral contraceptives (like ethinylestradiol).

Overdose and Missed Dose

• An overdose of Thiopental Sodium can result in severe respiratory and cardiovascular depression. Immediate medical intervention is critical.

• In the case where a dose is missed, it generally pertains to a controlled medical environment, hence managed directly by healthcare professionals.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Adjusting the timing of the medication may help manage some side effects.

• Staying hydrated by drinking adequate water can help alleviate minor side effects like headaches or dizziness.

Use in Driving and Operating Machinery

• Thiopental Sodium significantly impairs cognitive and motor functions; thus, patients are advised not to drive or operate heavy machinery after administration until fully recovered.

Use in Pregnancy and Lactation

• The safety of Thiopental Sodium in pregnancy and breastfeeding has not been established. It is advisable to avoid use during these periods unless specifically recommended by a doctor.

Caution in Other Conditions

• Patients with asthma or those who are elderly should exercise caution when using Thiopental Sodium due to the increased risk of respiratory depression.

• Individuals with low blood volume or severe anaemia should also be cautious due to the risk of hypotension.

Special Dietary and Lifestyle Recommendations

• Prior to receiving Thiopental Sodium, patients are advised to fast for at least 8 hours to minimise the risk of aspiration during sedation.

• Following surgery or anaesthesia with Thiopental Sodium, it is recommended to have someone to assist with home care as cognitive functions might be temporarily impaired.

• Avoid consuming alcohol or using medications that depress the central nervous system concurrently with Thiopental Sodium, as this can exacerbate effects.

• Maintain a well-balanced diet to support overall health recovery post-surgery. Ensure adequate hydration especially if experiencing side effects like nausea or dizziness post-procedure.

Frequently asked questions

Terms & Conditions