Saxagliptin

Expert Advice

Dosage Forms Available

• Saxagliptin is available in tablet form for oral administration.

Age and Dose Restrictions

• Saxagliptin is meant for use in adults and adolescents above 18 years of age.

Contraindications

• Saxagliptin is contraindicated in patients with a history of hypersensitivity to any of its components.

• It is also contraindicated in individuals with a history of pancreatitis.

Other Medications to Avoid

• This medicine interacts with strong inhibitors of CYP3A4/5 enzymes, which may significantly increase saxagliptin exposure. These include antifungals (e.g., ketoconazole, itraconazole), antiretrovirals (e.g., atazanavir, ritonavir, nelfinavir), macrolide antibiotics (e.g., clarithromycin, telithromycin), and other medications (e.g., indinavir, nefazodone, saquinavir).

Overdose and Missed Dose

• An overdose of Saxagliptin may lead to symptoms such as nausea, vomiting, and diarrhoea. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of Saxagliptin, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For nausea or abdominal discomfort after taking Saxagliptin, try taking it with food or a glass of water.

• If you experience dizziness after taking Saxagliptin, sit or lie down until the sensation passes.

Use in Driving and Operating Machinery

• Saxagliptin may cause dizziness in some individuals. If you experience dizziness after taking this medicine, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• The safety of Saxagliptin in pregnancy and lactation has not been established. Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

• Caution is advised when using Saxagliptin in patients with renal impairment or reduced kidney function. Dosage adjustments may be necessary based on kidney function.

• Patients with a history of heart failure should also use Saxagliptin cautiously under medical supervision.

Special Dietary and Lifestyle Recommendations

• Follow a balanced diet rich in whole grains, fruits, vegetables, and lean proteins to help manage blood sugar levels.

• Monitor carbohydrate intake to avoid blood sugar spikes.

• Engage in regular physical activity such as brisk walking, cycling, or swimming to improve insulin sensitivity.

• Maintain a healthy weight to reduce the burden on your body's ability to use insulin effectively.

• Avoid smoking and limit alcohol consumption as these can negatively impact blood sugar control and overall health.

Frequently asked questions

Terms & Conditions