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Oxymetazoline Hydrochloride

Uses of Oxymetazoline Hydrochloride

  • Oxymetazoline Hydrochloride is primarily used to manage nasal congestion caused by conditions such as the common cold, hay fever, sinusitis, and other respiratory allergies. It belongs to the class of alpha-adrenergic agonists.

  • Additionally, it is also used in the form of a topical cream for managing persistent facial redness associated with rosacea in adults.

Side effects of Oxymetazoline Hydrochloride

  • Temporary burning, stinging, or dryness in the nose

  • Sneezing

  • Runny nose

  • Nervousness

  • Nausea

How Oxymetazoline Hydrochloride works

  • Oxymetazoline Hydrochloride is an alpha-adrenergic agonist.

  • It works by stimulating alpha-adrenergic receptors in the blood vessels of the nasal mucosa. This causes vasoconstriction, or narrowing of the blood vessels, which reduces swelling and congestion in the nasal passages, making it easier to breathe.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Oxymetazoline Hydrochloride is available for use via the nasal route in the form of a spray.

  • It is also available as a topical cream for application on the skin.

Age and Dose Restrictions

  • This medicine is meant for adults and children above 6 years of age for nasal spray and adults for topical cream.

Contraindications

  • Oxymetazoline Hydrochloride is contraindicated in patients with hypersensitivity to any component of the formulation.

  • It should not be used by individuals with certain cardiovascular conditions such as uncontrolled hypertension or severe heart diseases.

Other Medications to Avoid

  • Oxymetazoline Hydrochloride can interact with monoamine oxidase inhibitors (such as phenelzine and isocarboxazid), beta-blockers (such as atenolol and propranolol), tricyclic antidepressants (like amitriptyline and clomipramine), and ergot alkaloids (such as ergotamine).

Overdose and Missed Dose

  • An overdose of Oxymetazoline Hydrochloride may lead to symptoms such as drowsiness, slow heartbeat, dizziness, or fainting. In serious cases where breathing difficulties or unconsciousness occurs, immediate medical attention is necessary.

  • If you forget to use this medicine, apply or use it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing dryness in the nose from the nasal spray, try inhaling steam or using saline drops to help moisturise the nasal passages.

  • For minor skin irritation from the cream, ensure to apply moisturiser after the medication has dried.

Use in Driving and Operating Machinery

  • Oxymetazoline Hydrochloride generally does not affect your ability to drive or operate machinery. However, if you experience dizziness or severe headaches as side effects, it is advisable to avoid such activities.

Use in Pregnancy and Lactation

  • The safety of Oxymetazoline Hydrochloride during pregnancy and lactation has not been fully established. Consult your doctor before using this medication while pregnant or breastfeeding.

Caution in Other Conditions

  • Individuals with thyroid disorders, diabetes, or difficulty urinating due to an enlarged prostate should use Oxymetazoline Hydrochloride with caution.

  • Additionally, inform your doctor if you have any pre-existing heart conditions before using this medicine.

Special Dietary and Lifestyle Recommendations

  • If you are using Oxymetazoline Hydrochloride for congestion relief, increase your intake of fluids like water, warm soups, and possibly herbal teas that may help soothe the throat and ease congestion.

  • Maintain a balanced diet rich in vitamins C and E which can help manage inflammation associated with rosacea when using the topical form.

  • Engage in stress-reducing activities such as yoga or meditation; stress can exacerbate symptoms of rosacea.

  • Protect your skin from extreme temperatures and wind which might trigger flare-ups when dealing with rosacea. Use gentle skincare products that do not irritate your skin.

Frequently asked questions

Yes, one of the rare but serious side effects of Oxymetazoline Hydrochloride is a fast, slow, or pounding heartbeat. If you experience this or any other unusual symptoms, consult your doctor immediately.

No, it is not recommended to use Oxymetazoline Hydrochloride for more than three days as it may lead to rebound congestion. Always follow the dosage instructions provided by your doctor.

Yes, you should consult your doctor before using Oxymetazoline Hydrochloride if you have heart disease, hypertension, thyroid disorders, diabetes, or difficulty urinating due to an enlarged prostate.

Yes, Oxymetazoline Hydrochloride is used topically in the form of a cream for managing persistent facial redness caused by rosacea in adults.

Avoid contact with eyes and lips when applying Oxymetazoline Hydrochloride cream. Always wash your hands after application.

Oxymetazoline Hydrochloride may interact with monoamine oxidase inhibitors (such as phenelzine and tranylcypromine), beta-blockers (like propranolol and metoprolol), tricyclic antidepressants (including amitriptyline and clomipramine), and ergot alkaloids (such as ergotamine and dihydroergotamine).

Symptoms of an overdose can include drowsiness, slow heartbeat, dizziness, and fainting. If someone has overdosed and has serious symptoms such as trouble breathing, contact emergency services immediately.

Terms & Conditions

Available medicines for OXYMETAZOLINE HYDROCHLORIDE
Wincold Oxy For Adults Nasal Spray 10ml
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Torex Oxy Adult Nasal Drops 10 ML
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Coldlyte Oxy Spray 15ml
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Clear Oxymeta Nasal Spray 10ml
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Steris Healthcare
Pack of 10 ML
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Oxynasocan Nasal Solution 10ml
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Naselin Nasal Solution 10ml
Naselin Nasal Solution 10ml
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₹60.58
MRP ₹84.00
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