Neomycin
Uses of Neomycin
Neomycin is mainly used for the management of superficial bacterial infections of the skin and eyes, and also for reducing the risk of infection in the intestines before bowel surgery. It belongs to the group of aminoglycoside antibiotics.
It is also used off-label in combination with other therapies for the management of hepatic encephalopathy, a neurological condition associated with liver disease.
Side effects of Neomycin
Local skin reactions (itching, redness, and rash)
Eye discomfort (stinging, burning)
Gastrointestinal issues (nausea, vomiting, and diarrhoea)
Hearing loss and ringing in the ears (rare)
How Neomycin works
Neomycin is an aminoglycoside antibiotic. It works by binding to the bacterial ribosomes, specifically the 30S subunit, causing disruption in the initiation complex and leading to a misreading of mRNA. This process inhibits protein synthesis within bacteria, eventually killing the bacteria.
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Written By
Bachelor of Dental Surgery
Reviewed By
Doctor of Medicine
Expert Advice
Dosage Forms Available
- Neomycin is available to use in the form of ointments or creams (applied topically), eye drops or ointments, and tablets (oral route).
Age and Dose Restrictions
- Neomycin is meant for use in both adults and children of age above 12 years.
Contraindications
- Neomycin is contraindicated in patients who have known hypersensitivity to aminoglycoside antibiotics.
- This medicine is not suitable for patients who have pre-existing kidney disease, hearing impairment or vertigo.
Other Medications to Avoid
- Neomycin may interact with systemic aminoglycosides (such as gentamicin and amikacin), leading to an increased risk of nephrotoxicity and ototoxicity.
Overdose and Missed Dose
- Overdose of Neomycin can lead to serious adverse effects such as ototoxicity and nephrotoxicity. If you suspect an overdose, it is crucial to seek immediate medical attention.
- In case you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
- Drinking plenty of fluids can help manage gastrointestinal side effects like nausea, vomiting, and diarrhoea.
- If you experience any skin reactions like itching, redness, or rash, avoid scratching the area and keep it clean and dry.
Use in Driving and Operating Machinery
- Neomycin may cause some side effects like vertigo or dizziness. Therefore, it is advisable to avoid driving or operating heavy machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
- It is always advisable to consult a doctor before using this medicine during pregnancy and breastfeeding.
Caution in Other Conditions
- Caution is advised when using Neomycin in patients with inflammatory bowel disease or intestinal ulcerations due to increased risk of absorption and toxicity.
Special Dietary and Lifestyle Recommendations
- Regularly cleaning the affected body area and keeping it dry can help manage skin infections.
- Regular hand washing can prevent the spread of bacteria causing eye or skin infections.
Frequently asked questions
Is Neomycin an antibiotic?
Yes, Neomycin is a type of antibiotic. It belongs to the class of medications known as aminoglycosides.
Can Neomycin cause mood changes?
Neomycin is not directly associated with affecting mood. However, individuals may react differently to medications, and if you notice unexpected mood changes, you should consult your doctor.
Can Neomycin affect menstrual cycles?
Neomycin is not associated with any impact on menstrual cycles. If you observe any unusual changes during your menstrual cycle, please consult your doctor.
Does Neomycin cause weight gain?
Neomycin is not generally known to cause weight gain. However, if you notice significant weight changes after starting this medicine, it is advisable to discuss this with your doctor.
Can someone develop an addiction to Neomycin?
Neomycin is not associated with addictive properties. It is an antibiotic, and it does not contain substances that can lead to addiction or dependency.
Are there natural alternatives to Neomycin?
While there are natural substances with antibacterial properties, they may not be as effective or suitable as prescribed antibiotics like Neomycin in treating specific bacterial infections. Always seek advice from your doctor before considering natural alternatives for medical conditions.
Is there a vegetarian or vegan version of Neomycin available?
The origin of Neomycin, whether animal-based or plant-based, depends on the manufacturer. Consult your pharmacist for detailed information about the origin of the ingredients in your medication.
Neomycin in other salts
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