The primary use of Metformin + Remogliflozin Etabonate + Vildagliptin is to manage blood sugar levels in adults with type 2 diabetes mellitus. This medication belongs to the group of antidiabetic medicines.
Additionally, it may be prescribed to patients whose blood sugar levels are not adequately controlled by metformin and one of the mono-components of the fixed-dose combination alone.
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Metformin + Remogliflozin Etabonate + Vildagliptin is a triple-acting antidiabetic combination.
Metformin is a biguanide. It manages blood sugar by lessening the production of glucose in the liver, reducing absorption of glucose in the intestines, and enhancing the body's responsiveness to insulin, which increases utilisation of glucose in your body.
Remogliflozin Etabonate is an SGLT2 inhibitor. It works by minimizing the reabsorption of glucose from your kidneys and increasing the amount of glucose excreted through urine, thus decreasing your overall blood sugar levels.
Vildagliptin is a DPP-4 inhibitor. It increases the amount of insulin produced and reduces the amount of glucagon made by your body in response to consumed food. By inhibiting DPP-4, it helps to control the breakdown of incretin hormones, therefore regulating your blood sugar levels.
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Metformin + Remogliflozin Etabonate + Vildagliptin is available in the form of tablets.
This medicine is taken orally, and the tablets should be swallowed whole with water.
This medicine is intended for use in adults only.
It is not recommended for use by children or adolescents under 18 years of age.
Metformin + Remogliflozin Etabonate + Vildagliptin is contraindicated in patients with type 1 diabetes mellitus.
It is also contraindicated in those experiencing diabetic ketoacidosis.
Patients with severe renal impairment (eGFR <30 mL/min/1.73m²) should not use this medicine.
It is contraindicated for those with a history of serious hypersensitivity reactions to any of its components.
This combination may interact with other antidiabetic agents (such as insulin, glipizide), medications affecting renal function (like furosemide), and medicines that impact glucose metabolism (like dexamethasone).
In the event of an overdose, supportive treatment should be initiated based on the patient's clinical signs and symptoms. For Metformin overdose, hemodialysis may be required to remove accumulated medicine.
If a dose of Metformin + Remogliflozin Etabonate + Vildagliptin is missed, it should be taken as soon as remembered, unless it is almost time for the next dose. In such cases, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage gastrointestinal upset, consider taking the medicine with food or adjusting the timing of the dose.
Increase fluid intake to help manage minor dehydration symptoms possibly caused by remogliflozin etabonate.
This medication may affect your ability to drive or operate heavy machinery, particularly if you experience dizziness or light-headedness as a side effect. Caution is advised.
The safety of using Metformin + Remogliflozin Etabonate + Vildagliptin during pregnancy and lactation has not been established. It should be used only if clearly needed and after consulting a doctor.
Caution is advised for patients with liver impairment as metformin accumulation can occur, leading to potential lactic acidosis.
Patients with moderate renal impairment should have their dosage adjusted accordingly.
Maintain a balanced diet rich in whole grains, fruits, vegetables, lean proteins, and healthy fats to help control blood sugar levels.
Regular physical activity can improve insulin sensitivity and help manage blood glucose levels effectively.
Monitor blood sugar levels regularly as recommended by your doctor to ensure effective management of diabetes.
Avoid excessive alcohol consumption as it can interfere with blood glucose control and potentially interact with metformin.
Stay hydrated, especially when taking remogliflozin etabonate, as it increases urinary glucose excretion which can lead to dehydration.
Manage stress through techniques such as yoga or meditation which can positively affect blood sugar levels.
Frequently asked questions
Several medications for managing diabetes, such as the combination of Metformin + Remogliflozin Etabonate + Vildagliptin, may indirectly affect blood pressure by improving overall health and reducing vascular complications linked to diabetes. However, they are not specifically designed to lower blood pressure. If you have concerns about your blood pressure while taking this medication, consult your doctor for advice.
No, it is not recommended to stop taking any prescription medication, including Metformin + Remogliflozin Etabonate + Vildagliptin, abruptly without consulting your doctor. Abrupt discontinuation may lead to a sudden rise in blood sugar levels and other complications.
There's some evidence that Metformin may contribute to slight weight loss in some people, and the addition of Remogliflozin Etabonate can also possibly promote weight loss by increasing glucose excretion in urine. However, individual responses can vary and it is important to discuss this with your doctor.
Metformin + Remogliflozin Etabonate + Vildagliptin needs to be taken exactly as advised by your doctor.
If you miss a dose, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and resume your usual dosing schedule. Avoid doubling up on doses to replace a missed one.
Metformin + Remogliflozin Etabonate + Vildagliptin can potentially cause dizziness as a side effect in some individuals, especially if blood glucose levels drop too low (hypoglycaemia). Always consult your doctor if you experience this or any other unusual symptoms.
This combination is contraindicated in patients with severe renal impairment. Patients with moderate renal impairment should have their dosage adjusted accordingly. Your doctor will advise you based on your specific condition.
Metformin + Remogliflozin Etabonate + Vildagliptin in other salts
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