Lidocaine / Lignocaine + Prilocaine

Expert Advice

Dosage Forms Available

• Lidocaine / Lignocaine + Prilocaine is available in a few different forms for topical application. These include a cream (2.5% lidocaine + 2.5% prilocaine), an ointment for mucous membranes (2.5% lidocaine + 2.5% prilocaine), a patch delivery system, an aerosol spray (2.5% lidocaine + 2.5% prilocaine), and compounded preparations for specific procedures.

Age and Dose Restrictions

• The Lidocaine / Lignocaine + Prilocaine combination is generally prescribed for adults and children over the age of 12. However, it can be used on younger children under specific circumstances or medical recommendations. For paediatric population, consideration is based on body weight and dosage to be administered.

Contraindications

• Patients who have known hypersensitivity to lidocaine, prilocaine, or other amide local anaesthetics should not use this medication.

• This medication is contraindicated in those with severe hepatic disease, hereditary or idiopathic methemoglobinemia, Glucose-6-phosphate dehydrogenase (G6PD) deficiency, and congenital or acquired pseudocholinesterase deficiency.

Other Medications to Avoid

• Lidocaine / Lignocaine + Prilocaine can interact with class III antiarrhythmic medications (such as amiodarone), medicines capable of inducing methemoglobinemia (such as nitrites, sulfonamides, and acetaminophen), CYP3A4 inhibitors (like erythromycin and cimetidine), sedatives and opioid analgesics. Always consult your doctor if you are taking any of these medications.

Overdose and Missed Dose

• Overdosing on Lidocaine / Lignocaine + Prilocaine may result in symptoms of dizziness, drowsiness, tinnitus, numbness around the mouth, dysgeusia, nausea, vomiting, and methemoglobinemia. In case of a suspected overdose, consult your doctor immediately.

• If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next application, skip the missed dose and stick to your regular schedule.

Management of Side Effects

Most side effects of Lidocaine / Lignocaine + Prilocaine are temporary and will resolve once you stop using the medicine. If you experience severe side effects such as urticaria or allergic reactions, immediately consult your doctor.

• To manage local effects such as itching or burning at the application site, avoid scratching and keep the area clean.

Use in Driving and Operating Machinery

• Lidocaine / Lignocaine + Prilocaine may cause dizziness or drowsiness in some individuals. If these symptoms occur, refrain from driving or operating heavy machinery until they subside.

Use in Pregnancy and Lactation

• There is insufficient data on the use of Lidocaine / Lignocaine + Prilocaine during pregnancy and lactation. It is essential to consult your doctor before using this medicine if you are pregnant or breastfeeding. Lidocaine should not be used in early stages of pregnancy unless benefit outweighs risks. Caution should be exercised when lidocaine is administered to a nursing woman.

Caution in Other Conditions

• Patients with severe cardiac disease, impaired cardiac conduction, bradycardia, or haemorrhagic diathesis should exercise caution while using Lidocaine / Lignocaine + Prilocaine.

• Individuals with impaired liver function may be more susceptible to toxicity from systemic absorption of this medication.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in fruits and vegetables to support overall health.

• Regular physical activity can help promote overall health and well-being.

• Limit consumption of alcohol as it might impact your body's ability to metabolize the medication.

• Ensure adequate hydration, especially if you use the medication for a prolonged period.

• Regularly monitor your skin for any changes or unusual symptoms and report them to your doctor promptly.

Frequently asked questions

Terms & Conditions