L-ornithinel-aspartate + Silymarin
Uses of L-ornithinel-aspartate + Silymarin
- L-Ornithine-Aspartate + Silymarin is primarily used for managing liver diseases. It belongs to the group of hepatoprotective and detoxifying medicines.
- Secondary uses include supportive treatment for toxic liver injury and as an adjunctive therapy in patients undergoing anti-viral treatment for viral hepatitis.
Side effects of L-ornithinel-aspartate + Silymarin
- Mild gastrointestinal disturbances
- Headache
- Pruritus (itching)
- Allergic skin reactions
How L-ornithinel-aspartate + Silymarin works
- L-Ornithine L-Aspartate is an amino acid-based formula. It plays a crucial role in the urea cycle, a process that removes toxic ammonia from the body. It increases the production of urea and glutamine in your liver, converting harmful ammonia into substances that your body can safely remove.
- Silymarin is a plant-based compound derived from milk thistle. It works as an antioxidant, which means it fights harmful substances called free radicals in the body. It also has anti-inflammatory properties, reducing swelling and irritation in the liver.
- Together, these components work to manage conditions like chronic hepatitis, alcoholic liver damage, non-alcoholic fatty liver disease and cirrhosis by detoxifying harmful substances, reducing inflammation, and protecting against further liver damage.
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Written By
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Reviewed By
Doctor of Medicine
Expert Advice
Dosage Forms Available
- L-Ornithine-Aspartate + Silymarin can be taken orally (tablets, capsules, and sachets).
Age and Dose Restrictions
- This medicine is intended for use in adults and children aged 12 years and above.
Contraindications
- This medication is contraindicated in patients with known hypersensitivity to either L-ornithine L-aspartate or silymarin.
- It is also not recommended for patients with severe kidney problems.
Other Medications to Avoid
- L-Ornithine-Aspartate + Silymarin can interact with antidiabetic agents (such as metformin and glipizide), sedatives (like diazepam and lorazepam), opioids (such as morphine and fentanyl), antidepressants (like fluoxetine and citalopram) and immunosuppressants (including sirolimus and tacrolimus).
Overdose and Missed Dose
- An overdose of L-Ornithine-Aspartate + Silymarin may lead to elevated levels of amino acids in the body and can cause symptoms like nausea, vomiting, and stomach cramps. Seek immediate medical attention if you suspect an overdose.
- If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, simply skip the missed one. Never take a double dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
- For managing mild gastrointestinal disturbances, consider taking the medication with meals.
- Drinking plenty of fluids may help to ease headaches.
- In case of skin itching (pruritus), a gentle moisturiser may provide some relief.
Use in Driving and Operating Machinery
- This medication does not typically affect the ability to drive or operate machinery. However, if you experience dizziness or sleepiness after taking this medicine, it is best to avoid such activities until you feel well again.
Use in Pregnancy and Lactation
- Always consult your doctor before using this medicine during pregnancy or while breastfeeding.
Caution in Other Conditions
- Patients with pre-existing gastrointestinal disorders like peptic ulcer disease should exercise caution when taking L-Ornithine-Aspartate + Silymarin.
- Also, individuals with hormone-sensitive conditions should also use this medication cautiously due to silymarin’s potential estrogenic effects.
Special Dietary and Lifestyle Recommendations
- Adopting a balanced diet rich in fruits, vegetables, lean protein, and whole grains can help maintain liver health.
- It's advisable to avoid processed foods and those high in saturated fats as they can exacerbate fatty liver disease.
Frequently asked questions
Can L-Ornithine-Aspartate + Silymarin affect my mood?
L-Ornithine-Aspartate + Silymarin is not directly associated with impacting mood. However, by managing liver diseases and associated symptoms, it can contribute to overall well-being and enhanced quality of life.
Is there a vegetarian or vegan version of L-Ornithine-Aspartate + Silymarin?
L-Ornithine-Aspartate + Silymarin formulations is generally considered vegetarian-friendly. However, certain formulations might contain non-vegetarian excipients like gelatine. Always check the packaging for details or consult your doctor or pharmacist for more precise information.
Is there a natural alternative to L-Ornithine-Aspartate + Silymarin?
While some natural products like milk thistle and certain amino acids can support liver health, they should not be used as an alternative to L-Ornithine-Aspartate + Silymarin without consulting your doctor first, especially if you are managing a specific liver condition.
Can L-Ornithine-Aspartate + Silymarin affect hormones?
Silymarin may have estrogenic effects. Therefore, it should be used with caution in patients with breast cancer. Always consult your doctor before starting any new medication.
Does L-Ornithine-Aspartate + Silymarin have an addictive potential?
There is no evidence to suggest that L-Ornithine-Aspartate + Silymarin is habit-forming or that it causes physical or psychological dependence.
Does L-Ornithine-Aspartate + Silymarin contain steroids?
No, L-Ornithine-Aspartate + Silymarin does not contain steroids. It comprises of two active ingredients L-ornithine L-aspartate, an amino acid, and silymarin, a flavonoid complex extracted from milk thistle.
Can L-Ornithine-Aspartate + Silymarin affect my sleep patterns?
L-Ornithine-Aspartate + Silymarin is not associated with impacting sleep patterns. If you experience changes in your sleep while taking this medicine, it could be due to underlying liver disease or other factors. Consult your doctor for advice.
L-ornithinel-aspartate + Silymarin in other salts
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