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L-ornithinel-aspartate + Pancreatin

Uses of L-ornithinel-aspartate + Pancreatin

  • L-Ornithine-L-Aspartate + Pancreatin is used to treat hepatic encephalopathy, indigestion, and pancreatitis (inflammation of the pancreas). 
  • L-Ornithine-L-Aspartate helps improve liver function by reducing ammonia levels, while Pancreatin aids in digestion by providing essential digestive enzymes. 

Side effects of L-ornithinel-aspartate + Pancreatin

  • Diarrhoea

  • Nausea

  • Vomiting

  • Abdominal pain

  • Headache

How L-ornithinel-aspartate + Pancreatin works

  • L-Ornithine-L-Aspartate + Pancreatin is a hepatoprotective and digestive enzyme combination.

  • L-Ornithine-L-Aspartate increases levels of ornithine and aspartic acid in the body, amino acids responsible for converting harmful ammonia into urea. The urea is then eliminated through urine, reducing ammonia levels in the blood and preventing brain damage. It also aids in the regeneration of damaged liver cells.

  • Pancreatin, on the other hand, supplements the naturally occurring digestive enzymes in the pancreas. These enzymes break down fats, carbohydrates and proteins in food so that they can be easily absorbed by the body. This helps improve digestion in individuals who have pancreatic enzyme deficiency.

  • The combined effect of these two components results in improved liver health and enhanced nutrient absorption.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • L-Ornithine-L-Aspartate + Pancreatin is available for use via oral route in the form of tablets, capsules and syrup.

Age and Dose Restrictions

  • This medicine is intended for use in adults and children above the age of 12 years.

Contraindications

  • L-Ornithine-L-Aspartate + Pancreatin is contraindicated in patients who have a known allergy to any of its components, including pork proteins.

  • Patients with kidney disease or gout should avoid this medication due to the potential for exacerbation of their condition.

Other Medications to Avoid

  • This medicine can interact with antacids and acid-suppressing drugs (such as omeprazole and ranitidine), anticoagulants (like warfarin, heparin), diabetes medicines (including insulin and gliclazide) and medicines metabolized by the liver (such as paracetamol, ropivacaine).

Overdose and Missed Dose

  • An overdose of L-Ornithine-L-Aspartate + Pancreatin may result in severe gastrointestinal issues like diarrhoea, nausea, vomiting, abdominal pain, and bloating. If you observe any of these symptoms, inform your doctor immediately.

  • If you miss a dose of this medication, take it as soon as you remember. However, if it is near the time of your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage gastrointestinal issues like diarrhoea, nausea, vomiting, abdominal pain or bloating, try taking the medication with meals and ensure you are staying well hydrated.

  • Over-the-counter anti-diarrheal or anti-emetic medications may be used as needed to manage these side effects.

Use in Driving and Operating Machinery

  • There is no noted effect on the ability to drive or operate machinery when using L-Ornithine-L-Aspartate + Pancreatin. However, if you experience dizziness or nausea, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • The safety of L-Ornithine-L-Aspartate + Pancreatin in pregnant or breastfeeding women is unknown. Therefore, it is advised to consult a doctor before using this medicine in pregnancy and breastfeeding.

Caution in Other Conditions

  • Extra caution should be taken when using L-Ornithine-L-Aspartate + Pancreatin in patients with diabetes, as the pancreatin component may affect blood glucose control.

Special Dietary and Lifestyle Recommendations

  • It may be beneficial to maintain a balanced diet that is low in fats and high in fibre to support digestion and liver function.

  • Avoid excessive consumption of alcohol as it can worsen liver damage and interfere with the action of this medicine.

  • Regular moderate exercise can help improve digestion and overall health.

Frequently asked questions

Although some athletes may use L-Ornithinel-Aspartate + Pancreatin for performance enhancement, it is worth noting that there is insufficient scientific evidence backing this claim. Therefore, it is advisable to consult a doctor before using this medication for any such off-label purposes.

There is no scientific evidence to suggest that L-Ornithinel-Aspartate + Pancreatin directly impacts mood or mental health. However, by helping manage hepatic encephalopathy and improving liver health, it may indirectly contribute to overall well-being.

Since pancreatin is derived from the pancreas of pigs, this medication may not be suitable for those following a strict vegetarian or vegan diet. Hence, you should discuss alternative medications with your doctor if you have such dietary restrictions.

There is no scientific evidence suggesting that the use of L-Ornithinel-Aspartate + Pancreatin can lead to addiction or cause withdrawal symptoms.

No specific food restrictions are mentioned in relation to L-Ornithinel-Aspartate + Pancreatin. However, it's advisable to maintain a healthy diet to support overall health and well-being.

L-Ornithinel-Aspartate + Pancreatin is usually taken with meals. Taking it before bed on an empty stomach may lead to stomach upset. Always follow your doctor's instructions on when to take this medicine.

The safety and effectiveness of L-Ornithinel-Aspartate + Pancreatin in children have not been established. Always consult your doctor before giving any medication to children.

Terms & Conditions


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