L-arginine
Uses of L-arginine
L-Arginine is primarily used to manage conditions related to poor blood flow and is an aminoacid.
It is also used for enhancing exercise performance, improving wound healing, and supporting immune function. Some clinical applications include managing symptoms of angina pectoris, aiding in erectile dysfunction, reducing blood pressure in hypertensive individuals, and potentially preventing necrotizing enterocolitis in preterm infants.
Side effects of L-arginine
Gastrointestinal issues like nausea
Abdominal pain
Bloating
Diarrhoea
Low blood pressure
How L-arginine works
L- Arginine is an amino acid. It works by playing a vital role in the production of nitric oxide, a compound that promotes the relaxation and widening of blood vessels (vasodilation), hence enhancing blood flow.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
This medicine can be taken orally (tablet, capsule and powder), or intravenous (infusion) route.
Age and Dose Restrictions
L-Arginine is suitable for use by adults and children.
Contraindications
This medicine is contraindicated in individuals with allergies to any of its components.
It should not be used by individuals with certain health conditions such as severe liver disease, kidney disease or recent heart attack.
Other Medications to Avoid
L-Arginine may interact with blood pressure-lowering medications (eg., lisinopril, atenolol), nitrates (eg., nitroglycerin, isosorbide), erectile dysfunction medications (eg., sildenafil, tadalafil) and blood-thinning medications (eg., warfarin and aspirin).
Overdose and Missed Dose
Overdose of L-Arginine can result in symptoms such as nausea, diarrhoea, weakness and a drop in blood pressure. If you experience these symptoms, consult your doctor immediately.
If you miss a dose of L-Arginine, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not take a double dose to make up for the missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage gastrointestinal side effects such as nausea, abdominal discomfort, and diarrhoea.
If L-Arginine causes sleep disturbances, adjust the timing of the dose to earlier in the day.
Use in Driving and Operating Machinery
This medicine does not typically affect your ability to drive or operate machinery. However, if you experience dizziness or lightheadedness after taking this medicine, avoid these activities until the effects wear off.
Use in Pregnancy and Lactation
It is advised to consult a doctor before taking this medicine during pregnancy and lactation.
Caution in Other Conditions
Individuals with liver or kidney disease should exercise caution while taking this medicine as these conditions can affect how the body metabolises this amino acid.
Special Dietary and Lifestyle Recommendations
Consuming a balanced diet rich in protein can help supply natural sources of L-Arginine. This includes food like red meat, poultry, fish, dairy, legumes, and whole grains.
Regular cardiovascular exercise can help improve circulation and maximise the benefits of L-Arginine's role in nitric oxide production.
Stress management techniques such as yoga or mindfulness meditation can help support overall health when taking L-Arginine.
Frequently asked questions
Is L-Arginine a natural substance?
Yes, L-Arginine is a semi-essential amino acid, meaning that it is naturally produced in the body. Additionally, it can also be found in various food sources such as red meat, poultry, fish, dairy products, eggs, legumes, nuts, and whole grains.
Does L-Arginine have any effect on my immune system?
L-Arginine plays a role in the development and function of T-cells, which are critical for a healthy immune response. Therefore, adequate levels of L-Arginine can help support your immune system.
Do I need a doctor's prescription to take L-Arginine supplements?
While L-Arginine supplements can often be purchased over the counter, it is highly recommended to consult your doctor before starting any new supplement. Your doctor can provide you with the correct dosage and guidance based on your health status and needs.
Will taking L-Arginine affect my menstrual cycle?
L-Arginine is not directly associated with affecting menstruation. However, if you notice any changes in your menstrual cycle after starting this supplement, consult your doctor to rule out other causes.
Can I use L-Arginine if I am vegan or vegetarian?
Yes, L-Arginine is suitable for both vegans and vegetarians. It is a semi-essential amino acid naturally present in the body and can also be obtained through plant-based food sources such as legumes, nuts, and whole grains.
Does L-Arginine have any effects on mood?
L-Arginine does not directly affect mood. However, promoting better blood circulation and overall health may indirectly contribute to improved mood and well-being.
Can L-Arginine contribute to improving athletic performance?
Yes, L-Arginine supplementation may enhance athletic performance by increasing muscle mass, strength, and recovery from exercise. However, it is advised to consult a doctor before starting any supplementation.
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