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Glycopyrrolate / Glycopyrronium + Indacaterol

Uses of Glycopyrrolate / Glycopyrronium + Indacaterol

The primary use of Glycopyrrolate / Glycopyrronium + Indacaterol is to manage airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. The medicine belongs to the group of anticholinergics and long-acting beta2-adrenergic agonists (LABAs).

Side effects of Glycopyrrolate / Glycopyrronium + Indacaterol

  • Cough

  • Headache

  • Dry mouth

  • Nausea

  • Muscle pain

How Glycopyrrolate / Glycopyrronium + Indacaterol works

  • Glycopyrrolate / Glycopyrronium + Indacaterol is a bronchodilator combination used for managing Chronic Obstructive Pulmonary Disease (COPD).

  • Glycopyrrolate / Glycopyrronium is an anticholinergic. It works by blocking a substance called acetylcholine on specific receptors (muscarinic receptors) in the airways. This stops the muscles around the airways from tightening, leading to a condition called bronchodilation, which helps in making breathing easier.

  • Indacaterol is a long-acting beta2-adrenergic agonist (LABA). It stimulates the beta2-adrenergic receptors in the lungs. This leads to relaxation of the smooth muscles in the bronchi (air passages in the lungs), improving airflow and making breathing more comfortable.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Glycopyrrolate / Glycopyrronium + Indacaterol is available for use via inhalation in the form of dry powder encapsulated in capsules.

  • The encapsulated dry powder formulation is designed to be administered using a specific inhaler device that is generally provided along with the medication.

Age and Dose Restrictions

  • This medicine is primarily meant for adult use.

  • It is typically prescribed for adults with chronic obstructive pulmonary disease (COPD), including conditions such as chronic bronchitis and emphysema.

Contraindications

  • Glycopyrrolate / Glycopyrronium + Indacaterol is contraindicated in patients with severe hypersensitivity to milk proteins.

  • It is also contraindicated in patients with hypersensitivity to either glycopyrrolate, Indacaterol, or any of the excipients used in the formulation.

Other Medications to Avoid

  • Glycopyrrolate / Glycopyrronium + Indacaterol may interact with other anticholinergics (such as atropine and ipratropium), other long-acting beta2-adrenergic agonists (such as salmeterol and formoterol), xanthine derivatives (such as theophylline and aminophylline), corticosteroids (like budesonide and fluticasone), diuretics (like furosemide and hydrochlorothiazide), monoamine oxidase inhibitors (MAOIs) including phenelzine and tranylcypromine, and tricyclic antidepressants (TCAs) such as amitriptyline and nortriptyline.

Overdose and Missed Dose

  • An overdose of this medicine may lead to symptoms such as blurred vision, dry mouth, and palpitations. If you observe these symptoms, inform your doctor immediately.

  • If you miss a dose of this medication, it should be taken as soon as remembered. However, if it is close to the time for the next dose, the missed dose should be skipped. Do not take an extra dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage some of the side effects, like dry mouth.

  • Resting and avoiding strenuous activities may help alleviate muscle pain.

  • For persistent cough or throat irritation, try drinking warm fluids or using a humidifier at home.

Use in Driving and Operating Machinery

  • Glycopyrrolate / Glycopyrronium + Indacaterol may cause dizziness or blurred vision in some individuals. Hence, it is advised to avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • It is advised to consult your doctor before using Glycopyrrolate / Glycopyrronium + Indacaterol during pregnancy and breastfeeding as it may not be safe to use.

Caution in Other Conditions

  • Patients with narrow-angle glaucoma, urinary retention, severe renal impairment, cardiovascular disorders (ischemic heart disease, arrhythmias, hypertension), convulsive disorders, and thyrotoxicosis should exercise caution when using this medication.

Special Dietary and Lifestyle Recommendations

  • Following a healthy diet rich in fruits, vegetables, lean proteins, and whole grains can help manage COPD.

  • Regular physical activity can improve lung function and overall well-being. However, it is important to consult your doctor before starting any new exercise regimen.

  • Smoking cessation is highly recommended for patients with COPD as it can significantly slow down the progression of the disease.

Frequently asked questions

No, Glycopyrrolate / Glycopyrronium + Indacaterol does not contain a steroid. It consists of an anticholinergic (Glycopyrrolate / Glycopyrronium) and a long-acting beta2-adrenergic agonist (Indacaterol).

Side effects related to sleep disturbances such as insomnia are not typically associated with Glycopyrrolate / Glycopyrronium + Indacaterol. However, individual reactions can vary. If you experience sleep-related issues after starting this medication, consult your doctor promptly.

There is no documented evidence showing that Glycopyrrolate / Glycopyrronium + Indacaterol affects fertility. Nonetheless, if you have concerns about fertility while taking this medication, consult your doctor.

No specific dietary restrictions have been reported for patients taking this medication. However, maintaining a healthy diet is always beneficial for overall health.

Glycopyrrolate / Glycopyrronium + Indacaterol is generally safe for daily use as it is intended for long-term management of COPD symptoms. However, it should always be taken under the supervision of a doctor.

Glycopyrrolate / Glycopyrronium + Indacaterol may begin to improve lung function within 5 to 15 minutes of inhalation.

Yes, you will need a doctor's prescription to purchase this medication as it is not available over the counter.

Terms & Conditions


Available medicines for GLYCOPYRROLATE / GLYCOPYRRONIUM + INDACATEROL
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