Gatifloxacin + Ornidazole is predominantly used to manage various bacterial infections including acute bacterial diarrhoea and travellers' diarrhoea. It belongs to the fluoroquinolone and nitroimidazole classes of antibiotics.
This medicine also helps manage conditions such as intestinal amebiasis, hepatic amebiasis, anaerobic bacterial infections and infections caused by giardia.
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Gatifloxacin, a fluoroquinolone antibiotic, works by inhibiting specific enzymes in the bacteria called DNA gyrase and topoisomerase IV. These enzymes are crucial for the bacteria to replicate and repair its DNA. By blocking these enzymes, gatifloxacin stops bacterial growth and leads to their death.
Ornidazole, a nitroimidazole antibiotic, is transformed into a toxic substance inside the bacterial cell. These substances damage the bacteria's DNA, proteins, and cell membrane, thereby killing the bacteria.
Together, Gatifloxacin + Ornidazole effectively manage a broad range of both aerobic (oxygen-requiring) and anaerobic (not requiring oxygen) bacterial infections, particularly those affecting the gastrointestinal tract.
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Gatifloxacin + Ornidazole is available for oral administration in the form of tablets.
This combination medicine is primarily meant for adults of age above 18 years.
Gatifloxacin + Ornidazole is contraindicated in patients with known hypersensitivity to gatifloxacin, ornidazole, or any other quinolone or nitroimidazole antibiotics.
Patients with a history of tendinitis or tendon rupture associated with quinolone use should not take this medicine.
It is also contraindicated in patients with myasthenia gravis.
Gatifloxacin + Ornidazole may interact with antacids, sucralfate, iron, calcium and zinc supplements (such as omeprazole, ranitidine, ferrous sulphate, calcium carbonate and zinc sulphate) and certain respiratory medicines (like theophylline and cyclosporine).
An overdose of Gatifloxacin + Ornidazole may cause severe nausea, vomiting, CNS and cardiovascular effects. In such cases, immediate medical attention should be sought.
If you miss a dose of this medicine, take it as soon as you remember it. However, if it is nearly time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.
Most side effects of Gatifloxacin + Ornidazole are temporary and usually resolve once your body adjusts to the medicine or when you discontinue it.
Drinking plenty of fluids may help manage side effects such as nausea and diarrhoea.
Eating small, frequent meals may help if you are experiencing stomach discomfort or loss of appetite due to this medicine.
As Gatifloxacin + Ornidazole can cause dizziness, it may affect your ability to drive or operate heavy machinery. Avoid such activities if you experience these symptoms after taking the medicine.
Gatifloxacin + Ornidazole falls under pregnancy category C, which means it should be used only if the potential benefits outweigh the risks.
Both gatifloxacin and ornidazole are secreted into breast milk, so you should avoid using this medicine while breastfeeding. Always consult your doctor before using any medication during pregnancy or lactation.
Patients with severe renal impairment should use Gatifloxacin + Ornidazole cautiously.
The same applies to patients with significant hepatic impairment, as ornidazole undergoes significant hepatic metabolism.
Eating a balanced diet rich in fibre can help maintain a healthy gut.
Washing hands properly before meals and after using the toilet can help prevent bacterial infections.
If you're travelling to places where these infections are common, take precautions with food and water to avoid diarrhoea.
Frequently asked questions
After oral administration, both gatifloxacin and ornidazole are rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations occur within 1-2 hours for gatifloxacin and 2-4 hours for ornidazole.
No, it is crucial to complete the full course of medication as prescribed by your doctor, even if your symptoms improve earlier. This ensures that the infection is completely cleared from the body and reduces the risk of the infection returning or becoming resistant to the medicine.
Gatifloxacin + Ornidazole is a combination of two antibiotics Gatifloxacin, which belongs to the fluoroquinolone class of antibiotics, and Ornidazole, which is a nitroimidazole antibiotic. It is not a steroid.
Common side effects of Gatifloxacin + Ornidazole include dizziness, but it does not specifically impact sleep. If you are experiencing unusual sleep patterns or insomnia, consult your doctor.
Gatifloxacin + Ornidazole is not associated with affecting fertility. If you have concerns regarding fertility and the use of this medication, it is best to consult with your doctor.
There are no natural alternatives to antibiotics like Gatifloxacin + Ornidazole that would be effective in managing bacterial infections. Remember, it is crucial not to self-medicate and always consult your doctor for appropriate medication.
While mood swings are not a common side effect of Gatifloxacin + Ornidazole, individual reactions can vary. If you experience severe mood changes while taking this medication, consult your doctor immediately.
Gatifloxacin + Ornidazole in other salts
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