Flunarizine + Propranolol

Expert Advice

Dosage Forms Available

• Flunarizine + Propranolol is available in the form of oral capsules and tablets.

Age and Dose Restrictions

• This medicine is intended for use by adults only.

Contraindications

• Flunarizine + Propranolol is contraindicated in patients with hypersensitivity to either flunarizine or propranolol.

• It is also contraindicated in individuals with bradycardia (slow heart rate), heart block, cardiac failure, bronchial asthma, severe peripheral arterial disease (abnormal narrowing of the arteries), significant liver or kidney impairment, Parkinson's disease, and a history of depression.

Other Medications to Avoid

• This combination may interact with other antihypertensives (e.g., lisinopril, metoprolol) diuretics (e.g., hydrochlorothiazide, furosemide), antiarrhythmics (e.g., lidocaine, amiodarone), antidepressants including SSRIs (e.g., fluoxetine) and tricyclic antidepressants (e.g., amitriptyline), antipsychotics (e.g., chlorpromazine, haloperidol), sedatives (e..g, diazepam), opioids (e.g., morphine and fentanyl), oral hypoglycaemics (e..g, glipizide, metformin), and NSAIDs (e..g, naproxen and ibuprofen).

Overdose and Missed Dose

• An overdose of Flunarizine + Propranolol can lead to severe bradycardia (slow heart rate), hypotension (low blood pressure), bronchospasm, and cardiac arrest. Symptoms might include profound dizziness, fainting, trouble breathing, and extreme weakness. Emergency medical care is crucial in cases of suspected overdose.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If experiencing drowsiness or sedation, consider taking the medication at bedtime.

• For dry mouth, increase fluid intake throughout the day.

Use in Driving and Operating Machinery

• This medicine might cause drowsiness or dizziness. If affected, you should avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Flunarizine + Propranolol should be used during pregnancy and breastfeeding only if clearly needed. It is important to discuss the risks and benefits with your doctor before taking this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

• Individuals with liver issues should be cautious when using Flunarizine + Propranolol due to its extensive hepatic metabolism. Those with kidney impairments must also exercise caution due to altered medicine clearance, which might require dose adjustment.

Special Dietary and Lifestyle Recommendations

• Maintain a consistent routine with your medication timing to avoid triggering migraine episodes.

• Avoid known dietary triggers for migraines which might include aged cheeses, red wine, chocolate, or processed foods containing nitrates or monosodium glutamate.

• Stress management techniques such as meditation or biofeedback may be beneficial in managing stress-related migraine triggers.

Frequently asked questions

Terms & Conditions