Etamsylate + Tranexamic Acid
Uses of Etamsylate + Tranexamic Acid
The primary use of Etamsylate + Tranexamic Acid is to manage heavy menstrual bleeding. It belongs to the group of haemostatic and antifibrinolytic medicines.
This combination may also be useful in managing periventricular haemorrhage in low birth weight infants and controlling bleeding during or after surgery.
Side effects of Etamsylate + Tranexamic Acid
Nausea
Vomiting
Diarrhoea
Muscle pain
How Etamsylate + Tranexamic Acid works
Etamsylate is a haemostatic agent. It works by increasing the ability of platelets, which are small blood components, to stick together and form a clot.
Tranexamic Acid is an anti-fibrinolytic. It slows down the breakdown of blood clots by preventing the conversion of plasminogen to plasmin, an enzyme that dissolves clots. This helps arrest and prevent excessive bleeding.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Etamsylate + Tranexamic Acid can be taken orally (tablet) and intravenously (injection).
Age and Dose Restrictions
This combination is intended primarily for use in adults aged 18 or older. It is not recommended for use in children.
Contraindications
This combination is contraindicated in patients with known hypersensitivity to either Etamsylate or Tranexamic Acid. It should not be used in patients with active intravascular clotting, subarachnoid haemorrhage or a history of thromboembolic events.
Other Medications to Avoid
This combination may interact with hormonal contraceptives (like combined oral contraceptives and progestogen-only pills), oestrogens (such as oestradiol), retinoids (like isotretinoin, tretinoin), and prothrombotic agents (such as Factor VIII concentrate).
Overdose and Missed Dose
An overdose of this medicine could potentially lead to more severe side effects such as visual disturbances, allergic reactions, and thromboembolic events. If you suspect an overdose, consult your doctor immediately.
If you miss a dose of this medication, take it as soon as you remember unless it is nearly time for your next dose. In such a case, skip the missed dose and continue with your normal schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage side effects like nausea and diarrhoea.
Taking this medicine with or after meals can help minimise gastrointestinal discomfort.
Use in Driving and Operating Machinery
Etamsylate + Tranexamic Acid does not typically affect your ability to drive or operate heavy machinery. However, if you experience side effects like dizziness or blurred vision, it is advisable to avoid such activities until the symptoms resolve.
Use in Pregnancy and Lactation
It is advisable to consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
This combination should be used with caution in patients with a history of thromboembolic disorders, renal impairment, or irregular menstrual bleeding of unknown cause.
Special Dietary and Lifestyle Recommendations
Regular relaxation and stress management techniques may help in managing irregular periods and associated symptoms.
It is advisable to monitor your menstrual cycle closely while taking this medication. If there is any significant change in the pattern or volume of bleeding, consult your doctor.
Frequently asked questions
Can Etamsylate + Tranexamic Acid cause any mood changes?
The combination of Etamsylate and Tranexamic Acid is not known to cause any significant mood changes. However, everyone's reaction to medication can be different, and if you notice any sudden mood changes, it is best to consult your doctor.
Does Etamsylate + Tranexamic Acid have any impact on hormone levels?
Etamsylate + Tranexamic Acid does not typically affect hormone levels. Their primary function is to manage heavy menstrual bleeding by improving the ability of platelets to form blood clots and preventing existing clots from breaking down.
Can I become dependent on Etamsylate + Tranexamic Acid?
Etamsylate + Tranexamic Acid is not known to cause physical or psychological dependence. It is used to manage heavy menstrual bleeding and does not have addictive properties.
Is Etamsylate + Tranexamic Acid safe for long-term use?
Etamsylate + Tranexamic Acid is generally used only during menstrual cycles where heavy bleeding is a problem, and long-term continuous use is not recommended. Always follow your doctor's instructions regarding the duration of use.
Can I take Etamsylate + Tranexamic Acid for nosebleeds?
While both Etamsylate and Tranexamic Acid are known to help manage bleeding, this medication combination is primarily indicated for the management of heavy menstrual bleeding. It is recommended to consult your doctor for appropriate treatment for nosebleeds.
How quickly does Etamsylate + Tranexamic Acid start working?
The exact time for the onset of action may vary between individuals based on their metabolism, but it generally begins to work within a few hours of taking it.
How long does Etamsylate + Tranexamic Acid stay in the body?
The exact half-life of Etamsylate + Tranexamic Acid varies from person to person and depends on many factors, including the individual's metabolism, age, and overall health. Your doctor or pharmacist can provide more specific information.
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