Dexrabeprazole
Uses of Dexrabeprazole
Dexrabeprazole is primarily used in the management of various acid-related gastrointestinal disorders including erosive or ulcerative gastroesophageal reflux disease (GERD), symptomatic GERD in adults and adolescents aged 12 years and older, and duodenal ulcers. It belongs to a class of medications known as proton pump inhibitors.
Other uses of Dexrabeprazole include the eradication of Helicobacter pylori to reduce the risk of duodenal ulcer recurrence (as part of combination therapy), and management of pathological hypersecretory conditions, such as Zollinger-Ellison syndrome.
Side effects of Dexrabeprazole
Headache
Diarrhoea
Nausea
Abdominal pain
Vomiting
How Dexrabeprazole works
Dexrabeprazole belongs to the category of medicines known as proton pump inhibitors.
It works by blocking the action of an enzyme system called H+/K+-ATPase found in the stomach. This enzyme system is critical for producing stomach acid. When Dexrabeprazole inhibits this system, it stops the final step of acid production in the stomach, leading to less gastric acid secretion. This effectively suppresses gastric acid production, providing relief from symptoms and contributing to healing in conditions associated with excessive stomach acid.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Dexrabeprazole can be taken orally (delayed-release tablets).
Age and Dose Restrictions
Dexrabeprazole is intended for use in adults and adolescents 12 years of age and older.
Contraindications
Dexrabeprazole is contraindicated in patients who have exhibited hypersensitivity to any component of the formulation or substituted benzimidazoles.
Other Medications to Avoid
Dexrabeprazole may interact with anticoagulants (such as warfarin), chemotherapeutic agents (such as methotrexate), cardiac glycosides (like digoxin), antiretroviral medicines (atazanavir, nelfinavir), kinase inhibitors (like erlotinib), immunosuppressants (like mycophenolate mofetil) and antiplatelet medicines (such as clopidogrel).
Overdose and Missed Dose
Overdose of Dexrabeprazole may result in symptoms like confusion, blurred vision, or abnormal heart rhythms. In such cases, medical attention should be sought immediately.
If a dose of Dexrabeprazole is missed, it should be taken as soon as remembered. However, if it is close to the time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to catch up.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids may help alleviate constipation or diarrhoea.
Resting and avoiding sudden movements can help manage dizziness or lightheadedness.
Use in Driving and Operating Machinery
Dexrabeprazole may cause dizziness in some users. Therefore, it is recommended to avoid driving or operating machinery until you are sure that the medicine does not affect your ability to perform these activities safely.
Use in Pregnancy and Lactation
It is advised to consult a doctor before using this medicine during these periods.
Caution in Other Conditions
Patients with severe liver disease should exercise caution when taking Dexrabeprazole as it may necessitate dose adjustment.
Special Dietary and Lifestyle Recommendations
Regularly eating meals rich in fibre and drinking plenty of fluids can help manage symptoms of GERD and ulcers.
It is recommended to avoid foods that trigger heartburn or acid reflux, such as spicy or fatty foods.
To reduce the risk of GERD symptoms, try not to lie down for at least 2 hours after meals.
Frequently asked questions
Does Dexrabeprazole have any effect on my mood?
No, according to the available research data, Dexrabeprazole does not have any known impact on mood or mental state.
Can Dexrabeprazole cause any hormonal changes?
No, there is no evidence to suggest that Dexrabeprazole causes hormonal changes.
Is Dexrabeprazole safe for vegetarians and vegans?
Yes, Dexrabeprazole is safe for vegetarians and vegans. However, it is advisable to check the product packaging for detailed information regarding the product's ingredients.
Is there a risk of developing an addiction to Dexrabeprazole?
No, Dexrabeprazole is not known to cause addiction or dependency.
Are there any natural alternatives to Dexrabeprazole?
While certain lifestyle modifications and dietary changes may help manage symptoms of gastroesophageal reflux disease (GERD) and other related conditions, they cannot replace the effectiveness of medicines like Dexrabeprazole. Always consult your doctor before trying alternative therapies or stopping prescribed medication.
What tests are required while taking Dexrabeprazole?
Your doctor may suggest regular follow-ups and possibly tests to monitor your response to Dexrabeprazole. This could include checking for signs of gastric malignancy in patients with healed GERD.
Are there alternative salts similar to Dexrabeprazole available?
Yes, there are several other proton pump inhibitors available which work in a similar manner to Dexrabeprazole. However, the choice of alternative medication should be based on your doctor's advice.
Dexrabeprazole in other salts
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