Deflazacort
STEROIDUses of Deflazacort
- Deflazacort is a corticosteroid used to manage Duchenne muscular dystrophy (DMD), a rare muscle disease in children and young adults caused by a lack of the protein dystrophin.
- It is also prescribed for various conditions, including asthma, arthritis, allergies, skin disorders, kidney and heart problems, digestive issues, eye conditions, blood disorders, and tumors.
Side effects of Deflazacort
- Cushingoid appearance
- Increased weight
- Increased appetite
- Upper respiratory tract infection
- Cough
- Pollakiuria
- Hirsutism
- Central obesity
- Nasopharyngitis
How Deflazacort works
- Deflazacort is a corticosteroid prodrug that works by reducing inflammation and suppressing the immune system.
- It does this through its active form, 21-desDFZ, which acts on the glucocorticoid receptor. This action helps manage symptoms in various conditions like Duchenne muscular dystrophy, asthma, and arthritis.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available for Deflazacort
- This medicine is available for use via the oral route (tablets and suspension).
Age And Dosage Restrictions for Deflazacort
- This medicine is meant for adults and children above 5 years of age.
Contraindications of Deflazacort
- Deflazacort is contraindicated in patients with known allergies to deflazacort and who have a systemic infection or recently taken vaccination containing live viruses.
Medications To Avoid With Deflazacort
- The use of Deflazacort is contraindicated with various medications, including anti-tuberculosis (anti-TB) agents such as rifampicin and rifabutin, analgesics, anti-seizure medications such as phenobarbitone, phenytoin, carbamazepine, and pyrimidine, as well as antifungal drugs like ketoconazole. Consultation with a healthcare professional is imperative before initiating any prescription or over-the-counter medications.
Overdose and Missed Dose
- In case of an overdose of this medicine, inform your doctor and follow the advice accordingly.
- If you forget to take this medicine, take it as soon as you remember, but avoid repeating the dose.
Using Machine
- This medicine may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.
Use in Pregnancy and Lactation
- This medicine is not recommended during pregnancy or breastfeeding.
Special Dietary & Lifestyle Recommendation
- Avoid alcohol when you are taking this medicine.
- Making lifestyle changes, including dietary modifications and regular exercise, is essential for the proper functioning of the muscles when taking this medicine.
- Do not take grapefruit juice when you are taking this medicine.
- Avoid sudden stoppage of this medicine as it may cause withdrawal symptoms like tiredness, weakness, body aches, muscle pain, and joint pain.
- The use of Deflazacort is contraindicated with various medications
Frequently asked questions
1. How much time does Deflazacort take to work?
This medicine starts showing its effects within a few hours after consumption.
2. What warnings and precautions should I take while taking Deflazacort?
Avoid usage in the presence of an allergic reaction (hypersensitivity) to any of its components. Refrain from using this medication concurrently with grapefruit juice, as it may elevate the risk of serious adverse effects through a potential drug interaction. It is advisable to seek advice from a doctor promptly.
3. Can I stop taking Deflazacort if I feel healthy?
Do not stop taking this medicine without consulting your doctor, even if you feel healthy.
4. Is it safe for patients with kidney or liver issues?
Consult your doctor before taking this medicine if you have kidney or liver issues to ensure its safety and proper dosage.
5. Will Deflazacort affect contraception?
No, this medicine does not affect contraception.Â
6. Does Deflazacort affect fertility?
No, this medicine does not affect fertility.
7. Is Deflazacort a steroid?
Yes, Deflazacort is a corticosteroid, which is a type of steroid. It is used to reduce inflammation and suppress the immune system in various conditions, such as autoimmune diseases and allergic reactions.
8. Is Deflazacort a painkiller?
No, Deflazacort is not a painkiller. While it can reduce inflammation and swelling, which may indirectly relieve pain, its primary function is to act as an anti-inflammatory and immunosuppressant.
9. Is Deflazacort an antibiotic?Â
No, Deflazacort is not an antibiotic. It does not kill or inhibit the growth of bacteria. It is a corticosteroid used to reduce inflammation and modulate the immune system.
Deflazacort in other salts
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