Dapoxetine + Tadalafil
Uses of Dapoxetine + Tadalafil
The primary use of Dapoxetine + Tadalafil is as a dual approach to manage premature ejaculation and improve erectile function in men. It belongs to the group of SSRIs and PDE5 inhibitors.
This combination medication can also be used by adult men with comorbid erectile dysfunction to achieve and maintain erections sufficient for satisfactory sexual activity.
Side effects of Dapoxetine + Tadalafil
Headache
Dizziness
Nausea
Diarrhoea
Flushing
How Dapoxetine + Tadalafil works
Dapoxetine + Tadalafil is a combination sexual function enhancer.
Dapoxetine is a selective serotonin reuptake inhibitor or SSRI. It works by increasing the availability of serotonin in the brain, a chemical messenger that plays a crucial role in ejaculation. By increasing the availability of serotonin in the brain, it helps delay ejaculation and prolongs sexual activity.
Tadalafil is a phosphodiesterase type 5 or PDE5 inhibitor. It works by stopping the action of the enzyme PDE5 present in the penis. This action results in relaxation of the smooth muscles and increased blood flow into the penis, helping to achieve and maintain an erection.
When combined, this combination works together to manage both premature ejaculation and erectile dysfunction, improving sexual satisfaction and performance.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Dapoxetine + Tadalafil is available in the form of tablets for oral administration.
Age and Dose Restrictions
This combination is intended for use in adult men aged 18 to 64 years.
Contraindications
Dapoxetine + Tadalafil is contraindicated in patients with severe liver disease, end-stage kidney disease requiring dialysis, and a history of non-arteritic anterior ischaemic optic neuropathy (NAION).
Other Medications to Avoid
This combination may interact with CYP3A4 inhibitors (such as ketoconazole, ritonavir), alpha-blockers (like doxazosin, tamsulosin), antihypertensives (including amlodipine, lisinopril) and other PDE5 inhibitors (such as sildenafil, vardenafil).
Overdose and Missed Dose
An overdose of this combination can lead to symptoms such as dizziness, vision changes, slow heart rate and fainting. If you suspect an overdose, seek medical attention immediately.
If you miss a dose of this medication, take it as soon as you remember. However, if it is near the time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage side effects like headaches, flushing, and dizziness.
Taking the medication with a meal can help reduce gastrointestinal side effects such as nausea and diarrhoea.
Use in Driving and Operating Machinery
This combination may cause side effects like dizziness or blurred vision that may affect your ability to drive or operate machinery. Avoid engaging in these activities if you experience these side effects.
Use in Pregnancy and Lactation
Dapoxetine + Tadalafil is not approved for use in women; therefore, its safety during pregnancy and lactation has not been established.
Caution in Other Conditions
Patients with a history of cardiovascular diseases or peptic ulcers should use this combination with caution.
Caution is advised for patients with anatomical deformation of the penis or predisposition to priapism.
Special Dietary and Lifestyle Recommendations
Limit intake of caffeine as it can exacerbate some side effects of the medicine like headache and dizziness.
Avoid smoking as it can interfere with erectile function.
Limit alcohol intake as it can exacerbate erectile dysfunction and interfere with the effectiveness of the medication.
Frequently asked questions
Is Dapoxetine + Tadalafil a steroid?
No, it is not a steroid. It is a combination medication comprising Dapoxetine, an SSRI, and Tadalafil, a PDE5 inhibitor.
Does the Dapoxetine + Tadalafil have any effect on sleep?
This combination does not typically affect sleep. However, individual reactions can vary, and if you experience sleep disturbances while taking this medication, it is recommended to consult your doctor.
Will Dapoxetine + Tadalafil affect fertility?
There is no evidence to suggest that Dapoxetine + Tadalafil impacts fertility. It is primarily used to manage premature ejaculation and improve erectile function in men.
Are there any particular diet restrictions while taking Dapoxetine + Tadalafil?
There are no specific dietary restrictions when taking Dapoxetine + Tadalafil. However, it is advisable to maintain a balanced diet for overall health.
Is it safe to take Dapoxetine + Tadalafil daily?
It is typically safe to take Dapoxetine + Tadalafil daily; however, the frequency should be determined by your doctor based on your individual condition and response to treatment.
How much time does Dapoxetine + Tadalafil take to work?
It starts working typically within 1-3 hours of consumption. The time may vary depending on individual response and other factors.
What is the best time to take Dapoxetine + Tadalafil?
Dapoxetine + Tadalafil should be taken 1-3 hours before anticipated sexual activity as per your doctor's advice.
Dapoxetine + Tadalafil in other salts
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