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Clomifene + Melatonin

Uses of Clomifene + Melatonin

  • Clomifene + Melatonin is primarily used for managing female infertility and is classified as a selective estrogen receptor modulator and sleep-regulating hormone.

  • This combination medication can also help women who are not ovulating regularly or have certain ovulatory disorders like PCOS.

Side effects of Clomifene + Melatonin

  • Ovarian enlargement and cysts

  • Hot flashes

  • Abdominal or pelvic pain

  • Nausea or vomiting

  • Visual disturbances

How Clomifene + Melatonin works

  • Clomifene + Melatonin is a combination used to manage infertility in women.

  • Clomifene is a selective oestrogen receptor modulator. It works by attaching to oestrogen receptors in the brain. This blocks the typical feedback of circulating oestrogen, leading to an increase in follicle-stimulating hormone (FSH) and luteinising hormone (LH) levels, which prompt the ovaries to produce eggs.

  • Melatonin is a hormone that regulates sleep. It also acts as an antioxidant and protects the ovaries from oxidative stress and damage at the cellular level. This may improve the quality of the eggs produced by the ovaries. Furthermore, it may play a role in regulating hormones for reproduction.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Clomifene + Melatonin is available in the form of oral tablets.

Age and Dose Restrictions

  • This medicine is intended for use by adult women only.

Contraindications

  • Clomifene + Melatonin is contraindicated in women with ovarian cysts not related to polycystic ovary syndrome (PCOS).

  • It should not be used by women with abnormal uterine bleeding of unknown origin, liver disease, or uncontrolled thyroid/adrenal dysfunction.

  • Women with organic intracranial lesions like a pituitary tumour should also avoid using this medicine.

Other medications to avoid

  • Clomifene + Melatonin can interact with anti-oestrogens (like tamoxifen), gonadorelin analogues (such as goserelin), aromatase inhibitors (like letrozole), and oral contraceptives (such as ethinylestradiol).

  • Melatonin may interact with anticoagulants (like warfarin), immunosuppressants (such as cyclosporine), diabetes medications (like metformin), and CNS depressants (like benzodiazepines).

Overdose and missed dose

  • An overdose of Clomifene + Melatonin may lead to symptoms like nausea, vomiting, visual disturbances, or pelvic pain. If you experience these symptoms, consult your doctor for guidance.

  • If you forget to take a dose of this medicine, take it as soon as you remember. However, do not double up on your dosage to make up for the missed one.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water may help with common side effects like nausea or vomiting.

  • Resting and lying down in a dark, quiet room may help manage headaches.

  • Warm compresses can help alleviate pelvic or abdominal pain.

Use in driving and operating machinery

  • Clomifene + Melatonin may cause dizziness, fatigue, or visual disturbances, which could affect your ability to drive or operate heavy machinery. Avoid doing so if you experience these side effects.

Use in pregnancy and lactation

  • Clomifene + Melatonin is not recommended for use during pregnancy or while breastfeeding. Always consult your doctor before using this medicine if you are pregnant or nursing.

Caution in other conditions

  • Women with pre-existing depression should use Clomifene + Melatonin with caution as it may worsen this condition.

  • Caution is advised for patients with a history of visual disturbances.

Special dietary and lifestyle recommendations

  • Maintaining a balanced diet rich in fruits, vegetables, lean protein, and whole grains can support overall health during fertility treatment.

  • Regular physical activity, such as walking or yoga, can help manage stress and maintain physical health. Always discuss any new exercise regimen with your doctor first.

  • Avoid excessive caffeine and alcohol consumption as they can adversely affect fertility.

Frequently asked questions

No, it is not a steroid. Clomifene is a selective oestrogen receptor modulator and Melatonin is a sleep-regulating hormone. Together, they are used to manage female infertility.

Yes, one of the components of this combination medicine, Melatonin, is a hormone that regulates sleep. However, it is primarily included in this medicine for its antioxidant properties to help improve egg quality.

There is no evidence to suggest that this combination is habit-forming; however, the effects of such a combination have not been extensively studied. It is crucial to consult a doctor before taking this medicine.

There are no specific diet restrictions mentioned for taking Clomifene + Melatonin. However, maintaining a healthy diet aids overall health and could potentially enhance fertility.

The safety and efficacy of daily use of Clomifene + Melatonin depend on your individual health condition and the doctor's recommendation. Always consult your doctor before modifying your medication regimen.

The exact time varies for each individual and depends on various factors including the nature and severity of the infertility problem. Always consult your doctor for precise information regarding your treatment plan.

The medicine is usually recommended to be taken at bedtime, as Melatonin helps regulate sleep. However, it is advisable to follow your doctor's instructions regarding the timing of this medication.

Terms & Conditions


Available medicines for CLOMIFENE + MELATONIN
Clomipure 50 Capsule 5
Clomipure 50 Capsule 5
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Pack of 5 Units
₹271.42
MRP ₹331.00
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Ova Plus 50mg Tablet 10
Ova Plus 50mg Tablet 10
Liveon Healthcare Pharma Pvt Ltd
Pack of 10 Units
₹204.18
MRP ₹249.00
18.00% OFF
Clomipreg M 100/3 MG Tablet 5
Clomipreg M 100/3 MG Tablet 5
Unimarck Healthcare Ltd
Pack of 5 Units
₹286.18
MRP ₹349.00
18.00% OFF
Goodova 100 Capsule 5
Goodova 100 Capsule 5
Akumentis Healthcare Ltd
Pack of 5 Units
₹380.48
MRP ₹464.00
18.00% OFF
Goodova 25 Capsule 5
Goodova 25 Capsule 5
Akumentis Healthcare Ltd
Pack of 5 Units
₹122.18
MRP ₹149.00
18.00% OFF
Clomipure 25 Capsule 5
Clomipure 25 Capsule 5
Akumentis Healthcare Ltd
Pack of 5 Units
₹162.36
MRP ₹198.00
18.00% OFF
Clomipure 100 Capsule 5
Clomipure 100 Capsule 5
Akumentis Healthcare Ltd
Pack of 5 Units
₹380.48
MRP ₹464.00
18.00% OFF
Goodova 50 Capsule 5
Goodova 50 Capsule 5
Akumentis Healthcare Ltd
Pack of 5 Units
₹246.82
MRP ₹301.00
18.00% OFF

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