Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine is primarily used to manage mixed skin infections involving bacteria, fungi, and/or inflammatory dermatoses. This medication belongs to a group of corticosteroids, antibiotics and antifungal medicines.
It may also be used to manage conditions such as infected eczema or dermatitis, infected psoriasis, mixed bacterial/fungal skin infections, and inflamed and infected cutaneous mycoses
Skin reactions at the application site (burning, stinging, itching)
Skin irritation
Redness
Dryness
Skin thinning (with long-term use)
Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine falls under a topical antimicrobial and anti-inflammatory therapeutic category.
Clobetasol Propionate is a potent corticosteroid. It reduces inflammation by inhibiting the release of substances that cause redness and itching in the skin.
Ofloxacin is an antibiotic belonging to the fluoroquinolone class. It kills bacteria by inhibiting their ability to replicate and repair DNA, interfering with their ability to multiply and survive.
Ornidazole, a nitroimidazole antibiotic, disrupts bacterial DNA, thereby killing bacteria as well as certain parasites and anaerobic organisms.
Terbinafine is an antifungal medication. It blocks the synthesis of ergosterol, a component essential for the cell membranes of fungi, thereby stopping fungal growth.
Doctor of Medicine
BMS, FMC, MD Resident
Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine is available as a topical cream, ointment, and lotion. The medicine is meant to be applied directly onto the affected areas of the skin.
This combination of medicines is intended for adults and children above 12 years of age.
Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine is contraindicated in individuals with known hypersensitivity to any of the components.
It is also contraindicated in patients with a history of gastrointestinal disease, liver impairment, or autoimmune disorders.
This combination may interact with oral or topical corticosteroids (such as prednisolone), other systemic antibiotics or antifungals (like itraconazole), NSAIDs (like diclofenac), antacids (like aluminium hydroxide), multivitamins containing zinc or iron, blood thinners (like heparin), and certain seizure medications (like phenytoin).
Overdose of Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.
If you forget to apply this medicine, apply it as soon as you remember. However, if it is close to the time for your next application, skip the missed dose and continue your normal application schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you experience local skin reactions like burning, stinging, itching, or redness, you may find it beneficial to apply the cream at night to minimise these effects.
Dryness at the application site can be managed by applying a moisturiser a few hours after applying the medication.
This medicine does not generally affect your ability to drive or operate machinery. However, if you experience any side effects such as dizziness or blurred vision, avoid driving or operating heavy machinery.
This medicine should be used only if the potential benefits justify the risks. Always consult with your doctor before using this medicine during pregnancy and lactation.
Patients with other bacterial, fungal, or viral infections, liver or kidney impairment, diabetes, epilepsy, heart conditions, gastrointestinal disease or autoimmune disorders should use this medication with caution, as these conditions may increase the risk of adverse effects.
Avoid wearing tight clothing that can cause skin irritation and spread the infection.
Avoid scratching the affected areas to prevent further inflammation and potential scarring.
Frequently asked questions
Yes, Clobetasol Propionate, one of the components of this combination, is a potent corticosteroid.
The medication does not directly affect sleep, but if you experience itching or discomfort at night due to your skin condition, it could potentially disrupt your sleep.
This medication should be used only for the duration prescribed by your doctor. Long-term use can increase the risk of side effects.
This medication is not directly associated with affecting the menstrual cycle. If you notice any changes, please consult your doctor.
No, you should continue using this medicine for the full prescribed course, even if your symptoms disappear before that. This will ensure complete management of the condition and prevent recurrence.
Yes, one of the rare side effects of this medicine is skin discolouration. If you notice any changes in your skin colour while using this medication, consult your doctor right away.
No, Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine is a prescription medicine and should only be used under the supervision of a healthcare professional. It is not available over the counter.
Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine in other salts
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