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Clindamycin + Tretinoin

Uses of Clindamycin + Tretinoin

  • Clindamycin + Tretinoin is primarily used for the management of acne vulgaris. It belongs to the category of combination medications consisting of an antibiotic and a retinoid.

Side effects of Clindamycin + Tretinoin

  • Dryness of the skin
  • Redness at the application site
  • Burning or stinging sensation
  • Itching and skin irritation
  • Peeling of the skin

How Clindamycin + Tretinoin works

  • Clindamycin is a lincosamide antibiotic. It works by inhibiting the protein synthesis of Propionibacterium acnes, a bacteria that causes acne inflammation. By doing this, it effectively reduces the growth of the bacteria contributing to acne development.
  • Tretinoin, on the other hand, is a derivative of vitamin A and acts as a retinoid. It promotes skin cell turnover by stimulating the shedding of old, hard skin cells and boosting the growth of new ones. By unclogging the pores and reducing sebum production, it aids in the healing of acne lesions and improves the overall appearance of the skin.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Clindamycin + Tretinoin can be applied topically (gel, cream, and lotion).

Age and Dose Restrictions

  • This medicine is meant for adults and children above 12 years of age.

Contraindications

  • This medicine is contraindicated in patients with known allergies to clindamycin or tretinoin.

Other Medications to Avoid

  • This combination may interact with other topical medications (benzoyl peroxide and salicylic acid) and oral antibiotics (erythromycin and tetracyclines).

Overdose and Missed Dose

  • Overdose of Clindamycin + Tretinoin is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.
  • If you forget to apply this medicine, apply it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For skin dryness and peeling, use a mild moisturiser.
  • If you experience skin redness or irritation, avoid sun exposure.

Use in Driving and Operating Machinery

  • Clindamycin + Tretinoin is not directly associated with affecting a person's ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • Women who are pregnant or breastfeeding should consult their doctor before using Clindamycin + Tretinoin, as the safety of this combination during these periods is not fully established.

Caution in Other Conditions

  • Patients with a history of gastrointestinal diseases like regional enteritis, ulcerative colitis, and antibiotic-associated colitis should use Clindamycin + Tretinoin with caution.

Special Dietary and Lifestyle Recommendations

  • Maintain a consistent skincare routine that includes cleansing, toning, and moisturising.
  • Avoid using harsh skincare products that can irritate the skin.
  • Limit sun exposure and use a broad-spectrum sunscreen with good SPF when going outdoors.
  • Stay hydrated and maintain a balanced diet rich in fruits and vegetables. Avoid foods high in sugars and unhealthy fats.
  • Avoid touching your face excessively, and ensure your hands are clean before applying skincare products or makeup.

Frequently asked questions

Clindamycin + Tretinoin is not directly associated with affecting sleep. Consult your doctor if you feel any changes in your sleeping pattern.

Clindamycin + Tretinoin is not directly associated with affecting fertility. Consult your doctor for specific details.

This medication is usually applied as directed by your doctor.

The usability of Clindamycin + Tretinoin depends on the individual's skin condition and their doctor's prescription.

The time taken for Clindamycin + Tretinoin to show its effect may vary among individuals based on their skin type and the severity of the acne.

The duration of treatment with Clindamycin + Tretinoin depends upon your skin condition and the doctor's prescription.

Clindamycin + Tretinoin usually requires a prescription and is not available over-the-counter.

Terms & Conditions


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