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Chlordiazepoxide + Mebeverine

Uses of Chlordiazepoxide + Mebeverine

  • Chlordiazepoxide + Mebeverine is primarily used to manage the symptoms of irritable bowel syndrome (IBS) and belongs to the group of antispasmodic and anxiolytic medicines.

  • There are no significant secondary uses for this combination.

Side effects of Chlordiazepoxide + Mebeverine

  • Dry mouth

  • Drowsiness

  • Dizziness

  • Nausea

  • Constipation

How Chlordiazepoxide + Mebeverine works

  • Chlordiazepoxide + Mebeverine is an anti-anxiety and antispasmodic combination.

  • Mebeverine is an antispasmodic. It works by directly relaxing the muscle fibres in the gut, preventing painful contractions and spasms. This helps to ease abdominal discomfort and pain.

  • Chlordiazepoxide is a benzodiazepine, a type of anti-anxiety medicine. It enhances the effect of a certain neurotransmitter in the brain called GABA. GABA decreases the activity of certain brain cells, causing a calming effect. This helps reduce anxiety, which can be a trigger for symptoms of conditions like irritable bowel syndrome.

  • By working together, these two components effectively manage the physical and psychological symptoms associated with conditions like irritable bowel syndrome.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlordiazepoxide + Mebeverine is available for oral use in the form of tablets.

  • Mebeverine is also available independently for oral use as regular tablets and sustained-release capsules.

  • Chlordiazepoxide is also available separately for oral use as tablets.

Age and Dose Restrictions

  • This combination medicine is primarily intended for adults. It is not generally recommended for use in children or adolescents under 18 years of age.

Contraindications

  • This medication is contraindicated in patients with severe liver disease, acute angina (narrowing or blockage of the gut), myasthenia gravis (a condition causing muscle weakness), and porphyria (a group of rare genetic disorders that affect the nervous system).

Other Medications to Avoid

  • This combination may interact with other anti-anxiety medications and sedatives, opioid painkillers (such as morphine and codeine), certain types of antidepressants (such as fluoxetine and sertraline), antihistamines (like cetirizine and loratadine), muscle relaxants, and certain antifungal and HIV medications (such as itraconazole and ritonavir).

Overdose and Missed Dose

  • An overdose of Chlordiazepoxide + Mebeverine could lead to extreme drowsiness, confusion, slurred speech, slow reflexes, difficulty breathing, or loss of consciousness. If you suspect an overdose, contact emergency services immediately.

  • If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor. Here are some tips to manage side effects:

  • Drinking plenty of water may help with side effects such as dry mouth and constipation.

  • Rest and avoid intense physical activity if feeling drowsy or dizzy.

  • If you experience nausea, take the medication with food.

Use in Driving and Operating Machinery

  • This combination medication may cause drowsiness and dizziness, affecting your ability to drive or operate machinery. Avoid such activities until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Chlordiazepoxide + Mebeverine should only be used during pregnancy or while breastfeeding if the potential benefits outweigh the risks. Always consult your doctor before starting this medication while pregnant or breastfeeding.

Caution in Other Conditions

  • This medication should be used with caution in patients with a history of liver or kidney disease, breathing difficulties, drug or alcohol addiction, depression, and certain blood disorders such as porphyria.

Special Dietary and Lifestyle Recommendations

  • Consuming a high-fibre diet can help manage symptoms of IBS.

  • Regular physical activity can help regulate bowel movements and reduce anxiety.

  • Limit intake of caffeine, alcohol, and spicy foods as they might exacerbate IBS symptoms.

  • Practice stress management techniques like meditation or yoga to help control IBS symptoms triggered by stress.

Frequently asked questions

Yes, Chlordiazepoxide, one of the active ingredients in this combination, belongs to a class of medications known as benzodiazepines which can potentially cause dependence or addiction if used for prolonged periods. However, the risk is minimised when the medicine is taken as directed by your doctor.

The absorption of Mebeverine and Chlordiazepoxide is not significantly affected by food, so you may take them with or without food (20 minutes before food). However, as some people may experience gastrointestinal discomfort, it is generally advisable to take this medicine with meals.

Chlordiazepoxide + Mebeverine does not typically affect appetite; however, individual responses may vary. If you notice any significant changes in your appetite while taking this medicine, please consult your doctor

Before taking any other medications along with Chlordiazepoxide + Mebeverine, it is important to consult your doctor to avoid potential drug interactions.

Chlordiazepoxide, one of the active ingredients in this combination, has sedative properties and can cause feelings of drowsiness and relaxation.

Coffee or tea does not interact with Chlordiazepoxide + Mebeverine. However, caffeine can stimulate the gut and may exacerbate symptoms in some individuals with irritable bowel syndrome (IBS). It would be prudent to limit consumption if you notice worsening of your symptoms.

Chlordiazepoxide, a part of this combination, acts on the nervous system and can potentially cause mood changes in some individuals. If you notice any significant changes in your mood or behavior, please consult your doctor.

Terms & Conditions


Available medicines for CHLORDIAZEPOXIDE + MEBEVERINE
Aloyrin C 135/5 MG Tablet 10
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Mycolon C Tablet 10
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Meva C Capsule 15
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Benizep 5/135 MG Capsule Sr 10
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Clistar M 135/5 MG Tablet 10
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