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Cefuroxime

ANTIBIOTIC

Uses of Cefuroxime

  • Cefuroxime is an antibiotic used to treat bacterial infections in various parts of the body. It belongs to a group of medicines called cephalosporins and works by killing bacteria or stopping their growth.
  • It is effective for treating pneumonia, lung infections, meningitis, gonorrhea, and infections of the skin, blood, bones, joints, and urinary tract. Cefuroxime can also be used before, during, and after surgery to prevent infections.

Side effects of Cefuroxime

The side effects of Cefuroxime are:

  • Rash
  • Vomiting
  • Allergic reaction
  • Increased liver enzymes
  • Nausea
  • Diarrhoea

How Cefuroxime works

Cefuroxime is a broad-spectrum cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis. Here’s how it works:

  • It binds to specific penicillin-binding proteins (PBPs) in the bacterial cell wall, essential for its synthesis and maintenance.
  • It disrupts the formation of peptidoglycan, a key component of the cell wall, leading to structural weakness.
  • The weakened cell wall causes the bacteria to burst and die.
  • It is effective against a variety of Gram-positive and Gram-negative bacteria, treating infections by targeting the bacterial cell wall.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

  • Doctors recommend Cefuroxime to treat bacterial infections and relieve your symptoms. Take this medication with meals to prevent stomach problems. If you're feeling better, don't stop taking your medication without completing the full course. If you stop it too soon, the infection may return and be more difficult to treat. This medication may cause diarrhoea as a side effect. The addition of probiotics to this medication regimen may be beneficial. You should consult a doctor if you experience stomach pain or observe blood in your faeces. If you experience any of the following side effects while taking this medication: itchiness, swelling of the face, throat, or tongue, breathing difficulty, discontinue use and consult your doctor immediately. Do not use the remaining medication to treat any future infections. Before taking any antibiotic, it is important to consult your doctor. This medication may cause dizziness and tiredness. Do not operate a motor vehicle or engage in any activity requiring mental concentration until you have evaluated how the medication will affect you. Alcohol should not be consumed while taking this medication because it could increase side effects. You should notify your doctor if you are pregnant, planning to become pregnant, or already breastfeeding.

Dosage Forms Available

  •  Cefuroxime can be combined orally (tablet, suspension) and intravenously (injection).

Age And Dose Restrictions

  • Cefuroxime is used for both adults and children over 3 months of age.

Contraindications

  • Cefuroxime is contraindicated in patients with a known allergy to cephalosporins or any component of the formulation. Patients with a history of severe allergic reactions to penicillins should also avoid Cefuroxime due to potential cross-reactivity.

Medications To Avoid With This Drug 

  • Avoid taking antigout medications (probenecid), gastric medications (cimetidine, famotidine ,omeprazole), and oral contraceptives. These medications may alter the safety and effectiveness of Cefuroxime.

Frequently asked questions

Yes, Cefuroxime is safe and effective for usage during pregnancy. However, there is a lack of human studies despite evidence of little or no harm to the fetus from those performed on animals.

Within 1 to 2 hours, you must experience the benefit of Cefuroxime.

Yes, it's likely safe to take Cefuroxime during breastfeeding. According to limited human studies, the medicine may not provide a significant risk to the unborn child.

Yes, patients with kidney problems should take precautions while using Cefuroxime. Some patients may need a dosage modification of Cefuroxime. If you have any problems, you should consult your doctor.

Yes, diarrhoea is a risk after taking Cefuroxime. Therefore, drink lots of fluids and take probiotics to avoid excessive fluid loss (dehydration). Do not use anti-diarrhoea medication on your own, if the disease worsens, consult your doctor.

Yes, patients with liver problems should take precautions while using Cefuroxime. Some patients may need a dosage modification of Cefuroxime. If you have any problems, you should consult your doctor.

Patients who are allergic to cephalosporins or other ingredients in Cefuroxime should not use this medication. Patients with a previous history of liver problems should not get treatments for this. As a result, let your physician be aware if you have a drug allergy.

No, please do not stop taking Cefuroxime without first consulting your doctor. There is a chance that an infection may return if it is suddenly stopped.

Yes, an allergic reaction may be caused by taking the medicine. Patients with a reported allergy to cephalosporins are recommended to avoid using it because of the risk of infection. You should consult a doctor if you have symptoms of an allergic response, such as hives, breathing problems, or swelling of the face, lips, tongue, or neck.

It is not recommended to use any oral birth control pills, medicines that reduced stomach acid (like antacids or omeprazole), drugs that suppress the immune system (like mycophenolate or mycophenolic acid), medicines that lower uric acid (like probenecid). It also interacts with vaccines for typhoid and BCG. Before using any prescription or over-the-counter medications, you must consult with your doctor.

No, it is ineffective against viral infections such as influenza and the common cold. Consult with your doctor to determine whether you need Cefuroxime for your condition.

Most cephalosporins should be taken on an empty stomach, about 1 hour before or 2 hours after meals. However, Cefuroxime (Ceftin) is an exception. Its absorption is actually increased when administered with food.

Cefuroxime is a second-generation cephalosporin antibiotic. It treats a wide range of infections, including those in the respiratory tract, ear, skin, genitourinary area, and bone. It’s also used for early Lyme disease and impetigo.

Yes, Cefuroxime is effective against UTIs caused by susceptible bacteria. It inhibits bacterial cell wall synthesis, helping to treat UTIs.

Cefuroxime, like penicillins, is a beta-lactam antibiotic. It binds to specific penicillin-binding proteins (PBPs) inside bacterial cell walls, inhibiting the final stage of cell wall synthesis.

You should notice a decrease in symptoms, and your infection should heal. The exact time to feel better depends on the infection’s severity.

Terms & Conditions


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