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Cefoperazone + Sulbactam

ANTIBIOTIC

Uses of Cefoperazone + Sulbactam

  • Cefoperazone + Sulbactam is an antibacterial combination used to treat various bacterial infections, including respiratory tract, urinary tract, blood, abdominal, skin, bone, and joint infections, as well as meningitis, endometrium infections, and gonorrhea.

Side effects of Cefoperazone + Sulbactam

  • Neutropenia 
  • Leukopenia 
  • Decreased haemoglobin
  • Decreased haematocrit 
  • Thrombocytopenia
  • Increased levels of alanine and aspartate aminotransferase
  • Increased levels of blood alkaline phosphatases

How Cefoperazone + Sulbactam works

  • Cefoperazone is an antibiotic that works by preventing the formation of bacterial cell walls. The cell wall is essential for the survival of bacteria. Hence, the bacteria fail to survive and cause infection. 
  • Sulbactam is a beta-lactamase inhibitor that reduces the resistance towards cefoperazone and enhances the activity of cefoperazone.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • This combination is available in injection form.

Age and Dose Restrictions

  • This combination should be used as per the dosage advised by the doctor’s prescription.

Contraindications

  • This combination is contraindicated in patients with a history of hypersensitivity to cefoperazone or sulbactam or in patients having vitamin K deficiency.

Other Medications To Avoid With This Medicine

  • Avoid taking aminoglycosides (amikacin) with this combination.

Overdose and Missed Dose

  • Overdose of this combination can cause seizures. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Use In Driving And Operating Machinery

  • No, this combination does not affect the ability to drive and use machinery. 

Use in Pregnancy and Lactation

  • This combination is not recommended during pregnancy. Caution is advised in breastfeeding women.

Caution in Other Conditions

  • Caution is advised in older adults and patients with kidney and liver impairment.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol consumption, as it may increase the risk of adverse side effects.
  • Incorporate fibre-rich foods into your diet as they are easily digested by your gut bacteria, promoting their growth. This can aid in restoring a healthy balance of gut bacteria following a course of antibiotics.
  • Maintain a balanced diet high in nutrients to support your overall health and immune system.
  • Ensuring proper hygiene is crucial.

Frequently asked questions

No, this combination is not recommended while pregnant. 

No, this combination is not recommended during breastfeeding. 

The dosage of this combination depends on factors like the severity of the infection, type of infection, weight and age of the patient, if the patient is taking any other antibiotics, if the patient is suffering from any liver and kidney ailments, etc. 

Be cautious about the use of this combination in liver diseases. Do not take this medication without a doctor’s consultation. 

Be cautious about the use of this combination in kidney diseases. Do not take this medication without a doctor’s consultation.

Terms & Conditions


Available medicines for CEFOPERAZONE + SULBACTAM
Cefnest 1 GM Injection 1
Cefnest 1 GM Injection 1
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₹48.81
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Zonamax Es Injection 1
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₹150.06
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Lactagard 1500 Injection 1
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Ipca Laboratories Pvt Ltd.
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₹257.48
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Zostum 1.5g Injection 1
Zostum 1.5g Injection 1
Zuventus Healthcare Ltd
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₹372.53
MRP ₹454.30
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Ceftop 1000/500mg Injection 1
Ceftop 1000/500mg Injection 1
Intel Pharmaceuticals
Pack of 1 Units
₹90.20
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Magnex Forte 1.5gm Injection 1
Magnex Forte 1.5gm Injection 1
Pfizer Ltd
Pack of 1 Units
₹597.83
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Viatran 1.5gm Injection 1
Viatran 1.5gm Injection 1
Cipla Ltd.
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₹351.71
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Lactagard 3000 Injection 1
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