Cefixime + Ofloxacin
ANTIBIOTICUses of Cefixime + Ofloxacin
- Cefixime + Ofloxacin is used together to treat a broad spectrum of bacterial infections, including those affecting the skin, ears, lungs, prostate, and urinary tract.
- Cefixime is a cephalosporin antibiotic that targets a wide range of bacteria, while Ofloxacin is a fluoroquinolone antibiotic that effectively treats infections by inhibiting bacterial DNA replication.
- This combination helps in effectively eliminating bacteria, reducing symptoms, and promoting faster recovery from various bacterial infections.
Side effects of Cefixime + Ofloxacin
- Diarrhoea
- Abdominal pain
- Nausea
- Indigestion
- Flatulence
- Insomnia
- Headache
- Dizziness
- Vomiting
- Itching
How Cefixime + Ofloxacin works
- Cefixime + Ofloxacin are antibacterial agents. They work together to combat bacterial infections.
- Cefixime is a cephalosporin antibiotic that inhibits bacterial cell wall synthesis, which prevents bacteria from growing and multiplying.
- Ofloxacin is a fluoroquinolone antibiotic that interferes with bacterial DNA replication, stopping bacteria from reproducing.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Cefixime + Ofloxacin can be taken orally (tablet and suspension).
Age and Dose Restrictions
- This combination can be used in children and adults.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to cefixime or/and ofloxacin.
Medications to Avoid with This Drug
- Avoid taking antacids, sucralfate, stomach acid reducers (cimetidine), immunosuppressants (cyclosporin), NSAIDs, antigout medications (probenecid), bronchodilators (theophylline), anticoagulants (warfarin), and antidiabetic agents (insulin, glyburide/glibenclamide). These medications may alter the safety and effectiveness of Cefixime + Ofloxacin.
Overdose and Missed Dose
- Overdose can cause confusion, dizziness, impairment of consciousness, convulsive seizures, and nausea, which need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
- If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Management of Side Effects
- Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- It is unlikely to impair the mental alertness or coordination required while driving.
Use in Pregnancy and Lactation
- Caution is advised during pregnancy and breastfeeding if this combination is prescribed.
Caution in Other Conditions
- Caution is advised in patients with hemolytic anaemia, severe diarrhoea, epilepsy, tendonitis and those with actual defects in glucose-6-phosphate dehydrogenase (G6PD) activity, myasthenia gravis, hypoglycemia, peripheral neuropathy, and kidney and liver impairment.
Special Dietary & Lifestyle Recommendation
- Finish the entire prescribed course, even if symptoms improve before completion, to ensure complete eradication of the infection.
- Limit or avoid alcohol consumption during the course of treatment, as they can potentially interact with the medications and affect their efficacy.
- Consider incorporating probiotics into your diet or as supplements to support gastrointestinal health, as antibiotics may affect the balance of gut bacteria.
- Ofloxacin may increase sensitivity to sunlight, so use sunscreen, wear protective clothing, and avoid excessive sun exposure.
Frequently asked questions
1. How much time do Cefixime + Ofloxacin take to work?
This combination typically show effectiveness within the first few days of treatment. However, the full course should be completed to eradicate the bacterial infection successfully.
2. Can Cefixime + Ofloxacin be used for respiratory infections?
Yes, this combination can be used for respiratory infections, including acute bronchitis and chronic bronchitis, as part of their broad-spectrum antibiotic activity.
3. Do Cefixime + Ofloxacin increase blood sugar levels?
No, this combination does not increase blood sugar levels. However, it may lower blood sugar levels.
4. Is Cefixime + Ofloxacin a habit-forming medicine?
This combination is not habit-forming and is generally safe when used as directed.
5. Can I drive after taking Cefixime + Ofloxacin?
This combination may cause dizziness. Do not drive, operate machinery, or do other activities that require mental alertness or coordination until you know how this medication affects you.
6. Is Cefixime + Ofloxacin available over the counter, or do I need a prescription?
This combination usually require a prescription and is unavailable over the counter.
7. Does Cefixime + Ofloxacin affect fertility?
This combination is not known to have a significant impact on fertility.
8. Does Cefixime + Ofloxacin cause dry mouth?
This combination may cause dry mouth as a rare side effect.
9. Can the use of Cefixime + Ofloxacin cause diarrhea?
Yes, the use of Cefixime + Ofloxacin can cause diarrhea. These antibiotics can disrupt the natural balance of bacteria in the gut, leading to gastrointestinal side effects like diarrhea. In some cases, it may cause a more serious condition called antibiotic-associated colitis.
10. Does the use of Cefixime + Ofloxacin help treat Urinary tract infections (UTIs)?
Yes, Cefixime + Ofloxacin are effective in treating urinary tract infections (UTIs). They work by targeting and eliminating the bacteria responsible for the infection, providing relief from symptoms and helping to clear the infection.
11. What are the instructions for storage and disposal of Cefixime + Ofloxacin?
Cefixime + Ofloxacin should be stored in a cool, dry place away from direct sunlight and moisture, typically at room temperature. Keep the medication out of reach of children and pets. For disposal, do not flush the medication down the toilet or pour it into a drain. Instead, follow your local guidelines for disposing of medications or ask your pharmacist for proper disposal methods.
Cefixime + Ofloxacin in other salts
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