Calcitriol/ Cholecalciferol + Elemental Calcium + Vitamin K27 is primarily used for the prevention and management of bone health conditions such as osteoporosis. It belongs to the group of bone health supplements.
Secondary uses include the correction of vitamin D and calcium deficiencies, hypocalcemia management, hypoparathyroidism management and preventive measures against cardiovascular calcification.
Constipation
Nausea
Dry mouth or metallic taste
Headache or dizziness
Fatigue or weakness
Calcitriol/ Cholecalciferol + Elemental Calcium + Vitamin K27 is a bone health combination.
Calcitriol, a form of vitamin D3, increases the absorption of calcium and phosphate from the intestines. It also helps with bone mineralisation and regulates parathyroid hormone (PTH) secretion, which is involved in calcium balance.
Elemental Calcium, the main component of our bones, ensures adequate calcium content, which is critical for achieving peak bone mass and maintaining bone mineral density.
Vitamin K2-7, in the form of menaquinone-7 (MK-7), acts as a catalyst for the enzyme γ-glutamyl carboxylase. This enzyme activates proteins that bind calcium to the bone matrix and prevents it from accumulating in the arteries. Thus, it directs calcium to the bones and keeps it out of arteries, helping to maintain a healthy skeleton and avoiding cardiovascular calcification.
Together, these ingredients work to support bone health, regulate calcium metabolism, and ensure optimal calcium utilization in the body.
Doctor of Medicine
BMS, FMC, MD Resident
Calcitriol/ Cholecalciferol + Elemental Calcium + Vitamin K27 is available in the form of oral tablets or capsules.
This medicine is meant for adult use.
Specifically, it is most commonly prescribed for adults who are at increased risk of bone density loss, such as the elderly or postmenopausal women.
Calcitriol/ Cholecalciferol + Elemental Calcium + Vitamin K27 is contraindicated in individuals with hypercalcemia (high blood calcium levels), hypervitaminosis D (excessive vitamin D), malabsorption syndrome (difficulty absorbing nutrients) and any known allergies to the ingredients.
This combination can interact with certain medications such as thiazide diuretics (such as hydrochlorothiazide), digitalis glycosides (like digoxin), corticosteroids (like prednisone), bile acid sequestrants (like cholestyramine), mineral oil, anticonvulsants (like phenobarbital and phenytoin) and anticoagulants (like warfarin).
An overdose of this combination may cause symptoms like weakness, headache, dizziness, dry mouth, metallic taste, constipation, nausea, vomiting or hypercalcemia. If you observe these symptoms, inform your doctor immediately.
If you miss a dose of this combination, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
If you experience constipation, try increasing your water and fibre intake.
If this medicine causes you to feel dizzy or fatigued, do not stand up quickly. Instead, get up slowly to prevent falls.
This combination may cause dizziness or fatigue. Therefore, if you experience these side effects, avoid driving a vehicle or operating heavy machinery.
Pregnant and breastfeeding women should consult their doctor before using Calcitriol/ Cholecalciferol + Elemental Calcium + Vitamin K27.
Patients with renal impairment or history of kidney stones should use this medication with caution as it may increase the risk of hypercalcemia and kidney stones.
Patients with granulomatous diseases such as sarcoidosis should also consult their doctor due to the risk of hypercalcemia.
Limit intake of sodium and caffeine as they can impede calcium absorption in the body.
Exposure to sunlight can help your body naturally produce vitamin D.
Regular weight-bearing exercises like walking, running or resistance training can help strengthen your bones.
Frequently asked questions
No, it is a prescription medication. It is not available for purchase over the counter.
The capsule or tablet formulation may contain animal-derived ingredients. You should consult your doctor or read the product label to ensure that it fits with your dietary choices.
There is no direct evidence to suggest that it can affect your mood. If you experience any unusual emotional changes while taking this medication, it is advised to consult your doctor.
There is no significant evidence to suggest that taking it will impact menstruation. If you notice any unusual changes in your menstrual cycle while taking this medication, consult your doctor.
No, you should continue to take it as prescribed by your doctor, even if you feel better or your symptoms have improved. Stopping the medication prematurely might lead to a resurgence of symptoms.
No, it is not known to cause dependency or addiction. It is safe to take as long as it is used as per the doctor's advice.
Although rare, in some cases, individuals might experience an allergic reaction to this combination. If you observe any allergic symptoms such as skin rash, itching, difficulty breathing, or swelling of the face/lips/tongue/throat while taking this medication, seek immediate medical help.
Calcitriol/ Cholecalciferol + Elemental Calcium + Vitamin K27 in other salts
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