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Benzalkonium Chloride + Timolol

Uses of Benzalkonium Chloride + Timolol

  • Benzalkonium Chloride + Timolol is primarily used to manage elevated intraocular pressure in patients suffering from open-angle glaucoma and ocular hypertension. This combination belongs to the group of ophthalmic medications.

Side effects of Benzalkonium Chloride + Timolol

  • Eye irritation

  • Mild burning or stinging sensation

  • Blurred vision

  • Headache

  • Dry eyes

How Benzalkonium Chloride + Timolol works

  • Benzalkonium Chloride + Timolol is an antihypertensive combination.

  • Timolol is a non-selective beta-adrenergic receptor blocker. It reduces the pressure inside the eyes by decreasing the production of aqueous humour—a fluid in the eye. This happens because it blocks beta-adrenergic receptors, leading to less cyclic AMP synthesis and, subsequently, a decrease in aqueous humor formation.

  • Benzalkonium Chloride is a quaternary ammonium compound that serves as an antimicrobial preservative. It helps maintain the sterility of the ophthalmic solution by preventing microbial growth.

  • Together, these two components manage the symptoms of conditions like glaucoma and ocular hypertension effectively by reducing intraocular pressure and ensuring the sterility of the solution.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Timolol is available for use via the ophthalmic route in the form of an eye drop solution.

Age and Dose Restrictions

  • This medication is meant for adult use primarily. Safety and effectiveness in paediatric patients have not been established.

Contraindications

  • This medicine is contraindicated in patients with bronchial asthma or a history of bronchial asthma.

  • It is also contraindicated in patients with severe chronic obstructive pulmonary disease (COPD), sinus bradycardia, second or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock.

  • Additionally, it is contraindicated in patients with known hypersensitivity to any component of the product.

Other Medications to Avoid

  • This combination may interact with oral beta-blockers (such as atenolol and propranolol), oral calcium channel blockers (like verapamil and diltiazem), catecholamine-depleting medicines (such as reserpine), digitalis glycosides (like digoxin), and medicines like epinephrine.

Overdose and Missed Dose

  • In case you happen to put a few extra drops of this combination in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose of this medicine, apply it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Dry eyes can sometimes be alleviated by blinking more frequently or using a room humidifier.

  • If you experience discomfort due to the eye drops, try to use them just before going to bed to decrease irritation during waking hours.

Use in Driving and Operating Machinery

  • Benzalkonium Chloride + Timolol may cause blurred vision or dizziness. You should not drive or operate heavy machinery if your vision is impaired after using these eye drops.

Use in Pregnancy and Lactation

  • The use of Benzalkonium Chloride + Timolol during pregnancy and lactation has not been extensively studied. Therefore, it is advised to consult a doctor before using this medicine during pregnancy and lactation.

Caution in Other Conditions

  • Caution should be exercised while using this medication in patients with cerebrovascular insufficiency, diabetes mellitus, thyrotoxicosis, myasthenia gravis, and hypoglycemia.

  • Additionally, individuals with corneal disorders or undergoing filtration surgery should also exercise caution.

Special Dietary and Lifestyle Recommendations

  • Regular eye check-ups are recommended for early detection and management of glaucoma or ocular hypertension.

  • Limited exposure to sunlight and protecting eyes from harmful UV rays can prevent damage to the eyes. Protect your eyes from excessive UV light by wearing sunglasses when outdoors.

Frequently asked questions

No, it is not a steroid. It is a combination of an antimicrobial preservative (Benzalkonium Chloride) and a non-selective beta-adrenergic receptor blocking agent (Timolol).

There is no direct evidence suggesting that this combination influences sleep. However, different individuals may react differently to medicines, and if you experience any changes in your sleep pattern while using this medicine, it is advisable to consult your doctor.

The combination of Benzalkonium Chloride + Timolol has not been reported to impact fertility directly. However, if you are planning to conceive or facing fertility issues, it is recommended to discuss your medical history and current medications with your doctor.

No specific diet restrictions are associated with the use of Benzalkonium Chloride + Timolol unless advised by your doctor. However, maintaining a balanced diet can contribute positively to overall health.

Yes, it is safe to use Benzalkonium Chloride + Timolol daily as prescribed by your doctor. Do not alter the dosage or discontinue the medication without consulting your doctor.

The onset of action can vary among individuals. Follow your doctor's instructions for regular use, and do not expect immediate results.

It is important to use this combination as instructed by your doctor.

Terms & Conditions


Benzalkonium Chloride + Timolol in other salts

BRIMONIDINE + TIMOLOLBENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINTIMOLOLBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + NEPAFENACBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + TOBRAMYCINOXYCHLORO COMPLEX + TIMOLOLBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDEBENZALKONIUM CHLORIDE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + BRIMONIDINEBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLLATANOPROST + TIMOLOLTIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + BROMFENACBENZALKONIUM CHLORIDE + MOXIFLOXACINDORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBRIMONIDINE + OXYCHLORO COMPLEX + TIMOLOLBENZALKONIUM CHLORIDE + GANCYCLOVIR
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