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Azithromycin + Cefpodoxime Proxetil

Uses of Azithromycin + Cefpodoxime Proxetil

  • Azithromycin + Cefpodoxime Proxetil is primarily used to manage a variety of bacterial infections and belongs to the group of macrolide and cephalosporin antibiotics.

  • It is also useful for managing respiratory tract infections like sinusitis, bronchitis, and pneumonia, as well as skin and soft tissue infections, urinary tract infections, sexually transmitted infections like gonorrhoea and chlamydia, and acute otitis media (middle ear infection) in children.

Side effects of Azithromycin + Cefpodoxime Proxetil

  • Diarrhoea

  • Nausea

  • Abdominal pain

  • Headache

  • Fatigue

How Azithromycin + Cefpodoxime Proxetil works

  • Azithromycin, a macrolide antibiotic, binds to the 50S subunit of the bacterial ribosomes. This inhibits protein synthesis within the bacteria, stopping their growth.

  • Cefpodoxime Proxetil is a cephalosporin antibiotic that disrupts the formation of bacterial cell walls by binding to penicillin-binding proteins. This kills the bacteria, thereby eradicating the infection.

  • Together, their combined action offers enhanced effectiveness against a wide spectrum of gram-positive and gram-negative bacteria.

Certified content

Written By

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Dr. Meenakshi MaruwadaMedical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • This medicine is available in tablet form for oral administration.

Age and Dose Restrictions

  • This antibiotic combination is indicated for use in adults and children who are older than 6 months of age.

  • The doctor determines the dosage based on the patient's weight, age, and the type and severity of the infection.

Contraindications

  • Azithromycin + Cefpodoxime Proxetil is contraindicated in patients with a known allergy to either of the two antibiotics or any other macrolide or cephalosporin antibiotics.

  • It should not be used by individuals who have a history of cholestatic jaundice or liver dysfunction associated with previous use of azithromycin.

Other Medications to Avoid

  • This antibiotic combination may interact with antacids (calcium and magnesium carbonates and bicarbonates), cardiac glycosides (eg., digoxin), antigout medications (eg., colchicine), antiepileptics(eg., phenytoin), asthma medication (eg., theophylline) and anticoagulants (eg., warfarin).

Overdose and Missed Dose

  • An overdose of Azithromycin + Cefpodoxime Proxetil may cause symptoms such as hearing loss or neurological symptoms like seizures. In case of an overdose, seek immediate medical attention.

  • If you missed a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Avoid doubling the doses.

Management of Side Effects

Most side effects are temporary and generally resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water may help alleviate gastrointestinal symptoms such as diarrhoea, nausea and vomiting.

  • Resting and limiting physical activity may help manage the fatigue and dizziness that some patients experience.

Use in Driving and Operating Machinery

  • Azithromycin + Cefpodoxime Proxetil may cause dizziness in some individuals. It is advisable to avoid driving or operating heavy machinery if you experience this side effect.

Use in Pregnancy and Lactation

  • The use of this medicine during pregnancy or breastfeeding is not recommended without a doctor's advice. Consult your doctor before taking this medication if you are pregnant or nursing.

Caution in Other Conditions

  • Patients with severe kidney impairment or myasthenia gravis should exercise caution when using this antibiotic combination.

  • Elderly patients, as well as those with existing kidney or liver disease, should be closely monitored while taking this medicine.

Special Dietary and Lifestyle Recommendations

  • Ensure to maintain a balanced diet that includes plenty of fruits, vegetables and lean proteins to strengthen your immune system.

  • Adequate hydration is important as it can help alleviate some side effects like dry mouth and helps in the recovery process.

  • Good personal hygiene practices, such as regular handwashing, can prevent the spread of bacterial infections.

  • It is recommended to get plenty of rest while recovering from an infection.

  • Refrain from smoking and limit alcohol consumption, as they can weaken your immune system and prolong recovery time.

Frequently asked questions

No, Azithromycin + Cefpodoxime Proxetil is not a steroid. It is an antibiotic combination that belongs to the macrolide and third-generation cephalosporin groups, respectively.

Azithromycin + Cefpodoxime Proxetil does not usually affect sleep. However, everyone is different, and this may affect some people differently. If you notice any unusual effects, consult your doctor.

There is no definitive evidence suggesting that Azithromycin + Cefpodoxime Proxetil affects fertility in humans. If you have any concerns about fertility, speak to your doctor.

No particular dietary restrictions are generally needed when taking Azithromycin + Cefpodoxime Proxetil. However, it is essential to maintain a balanced diet for general health.

Azithromycin + Cefpodoxime Proxetil should be taken as directed by your doctor, which could be daily or as required, depending on the type of infection being managed.

The onset of action may differ from person to person. However, most people might start experiencing symptom relief within 2-3 days of starting the medicine.

Azithromycin + Cefpodoxime Proxetil can be taken with or without food. The best time would be as recommended by your doctor.

Terms & Conditions


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