Home/Drugs By Ailments / Aspirin + Dipyridamole

Aspirin + Dipyridamole

Uses of Aspirin + Dipyridamole

  • The primary use of Aspirin + Dipyridamole is to reduce the risk of stroke and other blood clotting events in patients who have had a transient ischemic attack (TIA) or ischemic stroke due to a blood clot. This medicine is part of the antiplatelet group of medicines.

  • It is also used for the prevention of blood clots after heart valve replacement surgery.

Side effects of Aspirin + Dipyridamole

  • Headache

  • Dizziness

  • Nausea

  • Diarrhoea

  • Abdominal pain

How Aspirin + Dipyridamole works

  • Aspirin + Dipyridamole is a combination of two types of medicine known as antiplatelet agents.

  • Aspirin works by permanently inhibiting an enzyme called cyclooxygenase-1 (COX-1). This enzyme is responsible for making thromboxane A2, a substance that causes blood platelets to clump together and form clots. By stopping the production of thromboxane A2, aspirin helps to prevent blood clots.

  • Dipyridamole blocks an enzyme named phosphodiesterase, which usually breaks down a special molecule called cyclic adenosine monophosphate (cAMP). When there is more cAMP in the body, this helps to stop platelets from sticking together and forming clots. Additionally, dipyridamole increases the amount of adenosine outside cells, leading to the relaxation and widening of blood vessels.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Aspirin + Dipyridamole is available for oral use in the form of extended-release capsules. These capsules facilitate the slow release of medication to maintain a consistent effect over a longer period.

  • The route of administration for this medicine is oral, meaning it is taken by mouth. The capsules should be swallowed whole without crushing or chewing them.

Age and Dose Restrictions

  • This medicine is meant for adult use.

Contraindications

Aspirin + Dipyridamole is contraindicated in patients with:

  • Hypersensitivity to aspirin, dipyridamole, or any component of the formulation.

  • Severe renal (kidney) or hepatic (liver) impairment.

  • Active peptic ulcer disease.

  • Hemophilia or other bleeding disorders.

Other Medications to Avoid

  • This combination may interact with anticoagulants (such as warfarin, and heparin), nonsteroidal anti-inflammatory medicines (NSAIDs like ibuprofen, and naproxen), selective serotonin reuptake inhibitors (SSRIs like sertraline, fluoxetine), serotonin-norepinephrine reuptake inhibitors (SNRIs like duloxetine, venlafaxine), and antihypertensive medications (such as atenolol).

Overdose and Missed Dose

  • An overdose of Aspirin + Dipyridamole may lead to symptoms such as bleeding complications, severe headaches, dizziness, or gastrointestinal distress. If you suspect an overdose, it is crucial to seek immediate medical attention.

  • If you miss a dose of Aspirin + Dipyridamole, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For headaches or dizziness, consider resting in a quiet, dark room and ensure adequate hydration by drinking plenty of water.

  • If experiencing indigestion or abdominal discomfort, try eating smaller, more frequent meals instead of large ones.

Use in Driving and Operating Machinery

  • Aspirin + Dipyridamole can cause side effects such as dizziness or lightheadedness. These could potentially impair your ability to drive or operate heavy machinery. Avoid undertaking such tasks until you know how this medication affects you.

Use in Pregnancy and Lactation

  • The safety of Aspirin + Dipyridamole during pregnancy and lactation has not been established. If you are pregnant or breastfeeding, it is advised to consult your doctor before taking this medication.

Caution in Other Conditions

  • Caution should be exercised when using Aspirin + Dipyridamole in patients with asthma due to the risk of aspirin-induced bronchospasm.

  • Patients with gout should also use this medicine cautiously as aspirin may increase uric acid levels.

Special Dietary and Lifestyle Recommendations

To support overall cardiovascular health while managing conditions that Aspirin + Dipyridamole addresses:

  • Incorporate a heart-healthy diet rich in fruits, vegetables, lean proteins, and whole grains.

  • Limit intake of saturated fats, cholesterol, and sodium to help manage blood pressure and lipid levels.

  • Engage in regular physical activity such as brisk walking, swimming, or cycling for at least 150 minutes per week.

  • Avoid smoking and limit alcohol consumption to reduce cardiovascular risk.

  • Manage stress through relaxation techniques such as yoga, meditation, or deep breathing exercises.

Frequently asked questions

No, Aspirin + Dipyridamole is not typically used for pain relief. It is primarily used to reduce the risk of stroke and other blood clotting events in certain patients.

There is no specific evidence to suggest that Aspirin + Dipyridamole directly affects mood or behaviour. However, if you feel unusual changes in your mood or behaviour while taking this medication, you should consult your doctor.

There is no specific interaction between Aspirin + Dipyridamole and food. However, it is generally recommended to take the medication as prescribed by your doctor.

Aspirin + Dipyridamole can be safe for long-term use if prescribed by your doctor. However, regular monitoring may be required to check for potential side effects.

If you are lactose intolerant, you should inform your doctor before starting this medication as it may contain lactose.

Aspirin + Dipyridamole does not affect menstruation. However, it can increase the risk of bleeding, so it's important to consult your doctor if you have heavy periods.

No, this medication should not be given to pets unless specifically prescribed by a veterinarian.

Terms & Conditions


Available medicines for ASPIRIN + DIPYRIDAMOLE
Arreno Capsule 10
Arreno Capsule 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹34.44
MRP ₹42.00
18.00% OFF
Dynasprin 75/60 MG Tablet 10
Dynasprin 75/60 MG Tablet 10
Usv Pvt Ltd
Pack of 10 Units
₹28.76
MRP ₹35.07
18.00% OFF
Cardiwell Plus 75/40 MG Tablet 10
Cardiwell Plus 75/40 MG Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹11.32
MRP ₹13.80
18.00% OFF
Aggrenox 25/200 MG Capsule Er 60
Aggrenox 25/200 MG Capsule Er 60
Boehringer Ingelheim
Pack of 60 Units
₹2334.54
MRP ₹2847.00
18.00% OFF

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