Aspirin + Clopidogrel
ANTIPLATELETUses of Aspirin + Clopidogrel
- Aspirin + Clopidogrel is a medicine that helps prevent blood clots. It is used for people who have had heart problems like a heart attack, stroke, or chest pain.
- It also helps people who had certain heart procedures, like getting a stent, to avoid more heart problems in the future. This medicine makes it less likely for blood clots to form and cause trouble again.
Side effects of Aspirin + Clopidogrel
The side effects of Aspirin + Clopidogrel are:
- Nausea
- Diarrhoea
- Headache
- Abdominal pain
- Indigestion
- Weakness
How Aspirin + Clopidogrel works
- Aspirin + Clopidogrel works together to prevent blood clots by targeting different aspects of the clotting process.
- Aspirin inhibits platelet aggregation by blocking the enzyme cyclooxygenase (COX), which reduces the production of thromboxane A2, a substance that promotes platelet clumping.
- Clopidogrel, on the other hand, prevents platelet activation and aggregation by inhibiting the ADP receptor on platelets. This dual action helps to significantly reduce the risk of blood clots and subsequent cardiovascular events.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Aspirin + Clopidogrel is available for use via the oral route (tablets).
Age and Dose Restrictions
- This combination is meant for adults and children above 18 years of age.
Contraindications
- Aspirin + Clopidogrel is contraindicated in patients with known allergies to aspirin or clopidogrel or who have asthma and severe kidney or liver issues.
Other Medications To Avoid With This Medicine
- The combination of Aspirin + Clopidogrel is not recommended for use with HIV medications (ritonavir, cobicistat), blood thinners (warfarin, heparin), antipsychotics (fluoxetine, lithium), antidiabetics (glibenclamide, repaglinide), anti-cancer medications (methotrexate), gout medications (probenecid), anti-epilepsy medications (valproate, phenytoin), anti-inflammatory medications (ibuprofen), and medications for upset stomach (omeprazole). It is crucial to consult with your doctor before using any of the mentioned medications.
Use In Driving And Operating Machinery
- This combination may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.
Overdose and Missed Dose
- Overdose of this combination can cause dizziness, headache, confusion, prolonged bleeding, and gastric pain. Inform your doctor regarding these effects and follow the advice accordingly.
- If you forget to take this combination, take it as soon as you remember. But avoid repeating the dose.
Use in Pregnancy and Lactation
- Aspirin + Clopidogrel is not recommended during pregnancy or breastfeeding
Special Dietary & Lifestyle Recommendation
- Avoid alcohol when you are taking Aspirin + Clopidogrel.
- Individuals with a history of heart disease should consider lifestyle modifications, including dietary changes such as adopting a low-carbohydrate and low-fat diet in conjunction with Aspirin + Clopidogrel.
Frequently asked questions
1. How much time does Aspirin + Clopidogrel take to work?
This combination starts showing its effect within a few hours after ingestion.
2. What warnings and precautions should I take while taking Aspirin + Clopidogrel?
Notify your doctor of your use of this combination before any forthcoming surgical interventions or emergency hospital admissions, as it may elevate the potential for bleeding.
3. Can I stop taking Aspirin + Clopidogrel if I feel healthy?
Do not stop taking this combination without consulting your doctor, even if you feel healthy.
4. Is it safe for patients with kidney or liver issues?
Consult your doctor before taking this combination if you have kidney or liver issues to ensure its safety and proper dosage.
5. Does Aspirin + Clopidogrel affect fertility?
This combination is unlikely to impact fertility in both men and women. It is always recommended to consult with your doctor.
Aspirin + Clopidogrel in other salts
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