Amoxicillin + Clavulanic Acid
ANTIBIOTICUses of Amoxicillin + Clavulanic Acid
- Amoxicillin + Clavulanic Acid is a combination antibiotic used to treat various bacterial infections, including respiratory infections like sinusitis, bronchitis, and pneumonia, as well as ear infections (otitis media), urinary tract infections, skin infections, dental infections, and bacterial sinusitis.
- Amoxicillin, a penicillin-like antibiotic, works by stopping bacterial growth, while Clavulanic Acid helps enhance its effectiveness against resistant bacteria.
Side effects of Amoxicillin + Clavulanic Acid
- Vomiting
- Nausea
- Diarrhoea
How Amoxicillin + Clavulanic Acid works
- Amoxicillin + Clavulanic Acid are antibacterial agents.
- Amoxicillin, a penicillin-type antibiotic, inhibits bacterial cell wall synthesis, which is essential for bacterial growth and survival.
- Clavulanic acid, a beta-lactamase inhibitor, prevents bacteria from producing beta-lactamase enzymes that would otherwise neutralise amoxicillin.
- By combining these two components, the medication not only attacks bacteria directly but also protects amoxicillin from being broken down, thereby enhancing its efficacy against a broader range of bacteria.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Amoxicillin + Clavulanic Acid can be taken orally (tablet, chewable tablets and oral suspension) and intravenously (injections)
Age And Dose Restrictions
- It is intended for adults and children over 3 months of age with appropriate dosage.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Amoxicillin, Clavulanic Acid or other cephalosporin antibiotics. It is also contraindicated in patients with history of jaundice or hepatic dysfunction.
Medications To Avoid With This Drug
- Avoid taking anticoagulants (warfarin), antigout medications (probenecid), oral contraceptives, immunosuppressants (mycophenolate mofetil) and other antibiotics with this medicine. These medications may alter the safety and effectiveness of Amoxicillin and Clavulanic Acid.
Overdose And Missed Dose
- Overdose of this combination can cause nausea, vomiting, diarrhoea, and potential kidney issues. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
- If you forgot to take this combination, take it as soon as you remember. If the time for the next dosage is close, it is recommended to skip the missed one now and resume your regular dosage pattern. Never increase your dosage without consulting your doctor.
Management Of Side Effects
- Take this medicine with food to reduce gastrointestinal side effects, and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- Amoxicillin + Clavulanic Acid generally does not impair the ability to drive or operate machinery. However, if you experience dizziness or severe gastrointestinal symptoms, avoid such activities until you feel well.
Use In Pregnancy And Lactation
- Caution is advised while taking this medicine during pregnancy and breastfeeding.
Caution In Other Conditions
- Caution is advised in patients with kidney and liver impairment.
Special Dietary And Lifestyle Recommendation
- Limit or avoid drinking while taking this medication as it may reduce the antibiotic's effectiveness.
- Consume probiotics to help heal your gut flora. It might help restore the balance of the gut flora, which can be upset by antibiotic treatment and lead to stomach issues.
- Pay special attention to the dosage and timing of this medication. Do not miss doses or stop therapy too soon, even if you start to feel better, since this could result in antibiotic resistance and infection recurrence.
Frequently asked questions
1. Is Amoxicillin + Clavulanic Acid safe to use in pregnancy?
Yes, Amoxicillin + Clavulanic Acid is safe and effective for usage during pregnancy. However, there is a lack of human studies despite evidence of little or no harm to the fetus from those performed on animals.
2. How much time does Amoxicillin + Clavulanic Acid take to work?
Within 3 to 4 hours, you must be able to experience the benefit of the Amoxicillin + Clavulanic Acid take to work.
3. Is Amoxicillin + Clavulanic Acid safe for breastfeeding mothers?
Yes, it's likely safe to take Amoxicillin + Clavulanic Acid during breastfeeding. The medicine may not provide a significant risk to the unborn child, according to limited human studies.
4. Is it safe for patients with kidney disease to use Amoxicillin + Clavulanic Acid?
Yes, patients who have kidney problems should take precautions while using Amoxicillin + Clavulanic Acid. Some patients may need a dosage modification of Amoxicillin + Clavulanic Acid. If you have any problems, you should consult your doctor.
5. Does taking Amoxicillin + Clavulanic Acid causes diarrhea?
Yes, diarrhea is a risk after taking Amoxicillin + Clavulanic Acid. Therefore, drink lots of fluids and take probiotics to avoid excessive fluid loss (dehydration). Do not use anti-diarrhea medication on your own; if the disease worsens, consult your doctor.
6. Does taking Amoxicillin + Clavulanic Acid cause contraceptive failure?
Yes, the effectiveness of birth control contraceptives may be decreased by using Amoxicillin + Clavulanic Acid. While taking Amoxicillin + Clavulanic Acid, you should consult your doctor about the use of additional contraceptive methods (e.g., condom, diaphragm, spermicide).
7. What are the warnings and precautions should I take while taking Amoxicillin + Clavulanic Acid?
Patients with an allergy to penicillin or any other ingredients in Amoxicillin + Clavulanic Acid should not use this medication. Patients who have a previous history of liver problems should not get treatments for this. As a result, let your physician be aware if you have a drug allergy.
8. Should I stop taking Amoxicillin + Clavulanic Acid if I feel healthy?
No, please do not stop taking Amoxicillin + Clavulanic Acid without first consulting your doctor. There is a chance that an infection may return if Amoxicillin + Clavulanic Acid is suddenly stopped.
9. Does taking Amoxicillin + Clavulanic Acid cause an allergic reaction?
Yes, an allergic reaction may be caused by taking AMOXICILLIN AND CLAVULANIC ACID. Patients who have a reported allergy to penicillin are recommended to avoid using it because of the risk of infection. You should consult a doctor if you have symptoms of an allergic response, such as hives, breathing problems, or swelling of the face, lips, tongue, or neck.
10. Does taking Amoxicillin + Clavulanic Acid help in the treatment of hemorrhoids?
No, because Amoxicillin + Clavulanic Acid is an antibiotic, it is very difficult to ease the symptoms of hemorrhoids in any manner. Hemorrhoids, commonly called piles, are a result of enlarged veins in the area surrounding the anus.
11. Does taking Amoxicillin + Clavulanic Acid help in the treatment of cough, cold, and flu conditions?
No, Amoxicillin + Clavulanic Acid is ineffective against viral infections such as influenza and the common cold. Consult with your doctor to determine whether you need Amoxicillin + Clavulanic Acid for your condition.
Amoxicillin + Clavulanic Acid in other salts
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