Amiloride + Frusemide
Uses of Amiloride + Frusemide
- Amiloride + Furosemide is primarily used to manage high blood pressure (hypertension) and belongs to the group of diuretic medicines.
- This combination is also used to manage conditions such as heart failure and edoema, which are conditions characterised by fluid retention in the body.
Side effects of Amiloride + Frusemide
- Dizziness or lightheadedness
- Headache
- Fatigue
- Nausea and vomiting
- Diarrhoea
- Increased blood sugar levels
- Electrolyte imbalances
- Rashes or allergic reaction
If any severe or persistent symptoms occur, it is important to consult a healthcare provider.
How Amiloride + Frusemide works
- Amiloride + Furosemide belongs to the category of diuretics, commonly known as 'water pills'.
- Amiloride is a potassium-sparing diuretic. It works by acting on the distal tubules and collecting ducts of the kidneys. It stops the kidneys from absorbing too much sodium and keeps them from losing too much potassium.
- Furosemide is a loop diuretic. It works on a part of the kidney called the loop of Henle. Here, it stops the absorption of sodium, chloride, and potassium, promoting even more urine production and helping your body lose excess water and salts.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
- Amiloride + Furosemide is available for use via oral route in the form of tablets and a solution.The combination allows for convenient administration of both diuretics in a single dosage form.
Age and Dose Restrictions
- This medicine is generally prescribed to adults and children over 18 years of age.
Contraindications
- This combination is contraindicated in patients with known hypersensitivity to either medicine or any of the ingredients.
- It is also contraindicated in patients with anuria (inability to produce urine), severe kidney disease or renal failure, severe liver disease or hepatic coma, Addison's disease (adrenal insufficiency) and hyperkalemia (high blood potassium levels).
Other Medications to Avoid
- This combination may interact with angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril and enalapril), angiotensin receptor blockers (ARBs) (such as losartan and valsartan) and corticosteroids (like prednisone).
Overdose and Missed Dose
- Overdosing can cause symptoms such as severe dehydration, low blood pressure, and electrolyte imbalances. If you suspect you've taken too much of this medicine, seek immediate medical attention.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
- To manage dizziness or lightheadedness, avoid sudden changes in posture and rise slowly from a sitting or lying position.
- For managing nausea, try taking this medicine with food.
- Stay well hydrated to counteract the diuretic effect of the medicine and to prevent dehydration.
Use in Driving and Operating Machinery
- Amiloride + Furosemide may cause dizziness or lightheadedness. Therefore, it is advised to avoid driving or operating heavy machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
- The use of this combination during pregnancy and breastfeeding is not generally recommended unless deemed necessary by your doctor.
- Always consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
- Patients with kidney disease or liver disease should exercise caution when taking Amiloride and Furosemide.
- The combination should also be used with caution in patients with diabetes as it may affect blood glucose levels.
Special Dietary and Lifestyle Recommendations
- Maintain a low-salt diet to help control your blood pressure and reduce water retention.
- Regular monitoring of blood pressure is recommended for individuals on this medication.
- Routine blood tests may be required to check levels of potassium and other electrolytes while taking this medicine.
Frequently asked questions
Is Amiloride + Furosemide a diuretic?
Yes, Amiloride + Furosemide is a diuretic medication, which means it helps the body get rid of excess water and salt.
Does taking Amiloride + Furosemide have any effect on sleep?
Amiloride + Furosemide is not directly associated with affecting sleep. However, some people may experience side effects such as dizziness and fatigue that might indirectly affect their sleep patterns.
Can Amiloride + Furosemide affect my fertility?
Amiloride + Furosemide is not associated with affecting fertility in men or women. However, if you are planning to conceive, it is advisable to discuss it with your doctor before starting any medication.
Can I become dependent on Amiloride + Furosemide if I take it daily?
No, dependency or addiction has not been reported with the use of Amiloride + Furosemide.
Should I monitor my blood pressure while taking Amiloride + Furosemide?
Yes, regular monitoring of your blood pressure is advisable while taking this medication as it is used to manage high blood pressure.
Can I get Amiloride + Furosemide without a prescription?
As a rule of thumb, always consult your doctor before starting any medication. This combination is a prescription medication and should only be taken under the supervision of a doctor.
Does Amiloride and Furosemide affect mood?
While mood changes are not a commonly reported side effect of Amiloride and Furosemide, any new symptoms experienced after starting this medication should be reported to your doctor.
Amiloride + Frusemide in other salts
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